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114 related items for PubMed ID: 8967972

  • 1. Transgenic mice with high levels of superoxide dismutase activity are protected from the neurotoxic effects of 2'-NH2-MPTP on serotonergic and noradrenergic nerve terminals.
    Andrews AM, Ladenheim B, Epstein CJ, Cadet JL, Murphy DL.
    Mol Pharmacol; 1996 Dec; 50(6):1511-9. PubMed ID: 8967972
    [Abstract] [Full Text] [Related]

  • 2. 2'-NH2-MPTP in Swiss Webster mice: evidence for long-term (6-month) depletions in cortical and hippocampal serotonin and norepinephrine, differential protection by selective uptake inhibitors or clorgyline and functional changes in central serotonin neurotransmission.
    Andrews AM, Murphy DL.
    J Pharmacol Exp Ther; 1993 Dec; 267(3):1432-9. PubMed ID: 8263805
    [Abstract] [Full Text] [Related]

  • 3. The role of membrane and vesicular monoamine transporters in the neurotoxic and hypothermic effects of 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine (2'-NH(2)-MPTP).
    Numis AL, Unger EL, Sheridan DL, Chisnell AC, Andrews AM.
    Mol Pharmacol; 2004 Sep; 66(3):718-27. PubMed ID: 15322265
    [Abstract] [Full Text] [Related]

  • 4. Neuronal and astroglial responses to the serotonin and norepinephrine neurotoxin: 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine.
    Luellen BA, Miller DB, Chisnell AC, Murphy DL, O'Callaghan JP, Andrews AM.
    J Pharmacol Exp Ther; 2003 Dec; 307(3):923-31. PubMed ID: 14561848
    [Abstract] [Full Text] [Related]

  • 5. 2'-NH(2)-MPTP [1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine] depletes serotonin and norepinephrine in rats: a comparison with 2'-CH(3)-MPTP [1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine].
    Unger EL, Mazzola-Pomietto P, Murphy DL, Andrews AM.
    J Pharmacol Exp Ther; 2002 Nov; 303(2):527-33. PubMed ID: 12388632
    [Abstract] [Full Text] [Related]

  • 6. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1.
    Szapacs ME, Numis AL, Andrews AM.
    Neurobiol Dis; 2004 Aug; 16(3):572-80. PubMed ID: 15262269
    [Abstract] [Full Text] [Related]

  • 7. The neurotoxin 2'-NH2-MPTP degenerates serotonin axons and evokes increases in hippocampal BDNF.
    Luellen BA, Szapacs ME, Materese CK, Andrews AM.
    Neuropharmacology; 2006 Mar; 50(3):297-308. PubMed ID: 16288930
    [Abstract] [Full Text] [Related]

  • 8. Sustained depletion of cortical and hippocampal serotonin and norepinephrine but not striatal dopamine by 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine (2'-NH2-MPTP): a comparative study with 2'-CH3-MPTP and MPTP.
    Andrews AM, Murphy DL.
    J Neurochem; 1993 Mar; 60(3):1167-70. PubMed ID: 8094744
    [Abstract] [Full Text] [Related]

  • 9. Effects of noradrenergic lesions on MPTP/MPP+ kinetics and MPTP-induced nigrostriatal dopamine depletions.
    Fornai F, Alessandrì MG, Torracca MT, Bassi L, Corsini GU.
    J Pharmacol Exp Ther; 1997 Oct; 283(1):100-7. PubMed ID: 9336313
    [Abstract] [Full Text] [Related]

  • 10. Fluoxetine and desipramine selectively attenuate 2'-NH2-MPTP-induced depletions in serotonin and norepinephrine.
    Andrews AM, Murphy DL.
    Eur J Pharmacol; 1993 Dec 07; 250(2):215-21. PubMed ID: 8112382
    [Abstract] [Full Text] [Related]

  • 11. Potential neuroprotective effect of t-butylhydroquinone against neurotoxicity-induced by 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'-methyl-MPTP) in mice.
    Abdel-Wahab MH.
    J Biochem Mol Toxicol; 2005 Dec 07; 19(1):32-41. PubMed ID: 15736157
    [Abstract] [Full Text] [Related]

  • 12. Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Part 1: Systemic administration.
    Giovanni A, Sieber BA, Heikkila RE, Sonsalla PK.
    J Pharmacol Exp Ther; 1994 Sep 07; 270(3):1000-7. PubMed ID: 7932147
    [Abstract] [Full Text] [Related]

  • 13. Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity.
    Przedborski S, Kostic V, Jackson-Lewis V, Naini AB, Simonetti S, Fahn S, Carlson E, Epstein CJ, Cadet JL.
    J Neurosci; 1992 May 07; 12(5):1658-67. PubMed ID: 1578260
    [Abstract] [Full Text] [Related]

  • 14. Evidence for a dissociation between MPTP toxicity and tyrosinase activity based on congenic mouse strain susceptibility.
    Hofele K, Sedelis M, Auburger GW, Morgan S, Huston JP, Schwarting RK.
    Exp Neurol; 2001 Mar 07; 168(1):116-22. PubMed ID: 11170726
    [Abstract] [Full Text] [Related]

  • 15. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the rat: characterization and age-dependent effects.
    Jarvis MF, Wagner GC.
    Synapse; 1990 Mar 07; 5(2):104-12. PubMed ID: 2309157
    [Abstract] [Full Text] [Related]

  • 16. Attenuation of 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine induced nigrostriatal toxicity in mice by N-acetyl cysteine.
    Sharma A, Kaur P, Kumar V, Gill KD.
    Cell Mol Biol (Noisy-le-grand); 2007 Apr 15; 53(1):48-55. PubMed ID: 17519111
    [Abstract] [Full Text] [Related]

  • 17. Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity.
    Choi JY, Jang EH, Park CS, Kang JH.
    Free Radic Biol Med; 2005 Mar 15; 38(6):806-16. PubMed ID: 15721991
    [Abstract] [Full Text] [Related]

  • 18. Age-dependent effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): correlation with monoamine oxidase-B.
    Walsh SL, Wagner GC.
    Synapse; 1989 Mar 15; 3(4):308-14. PubMed ID: 2787063
    [Abstract] [Full Text] [Related]

  • 19. CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons In vivo.
    Saporito MS, Brown EM, Miller MS, Carswell S.
    J Pharmacol Exp Ther; 1999 Feb 15; 288(2):421-7. PubMed ID: 9918541
    [Abstract] [Full Text] [Related]

  • 20. Neuroprotective effect of arundic acid, an astrocyte-modulating agent, in mouse brain against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity.
    Himeda T, Kadoguchi N, Kamiyama Y, Kato H, Maegawa H, Araki T.
    Neuropharmacology; 2006 Mar 15; 50(3):329-44. PubMed ID: 16303147
    [Abstract] [Full Text] [Related]

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