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178 related items for PubMed ID: 8971140

  • 1. Pharmacokinetic analysis of chloral hydrate and its metabolism in B6C3F1 mice.
    Abbas RR, Seckel CS, Kidney JK, Fisher JW.
    Drug Metab Dispos; 1996 Dec; 24(12):1340-6. PubMed ID: 8971140
    [Abstract] [Full Text] [Related]

  • 2. A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice.
    Abbas R, Fisher JW.
    Toxicol Appl Pharmacol; 1997 Nov; 147(1):15-30. PubMed ID: 9356303
    [Abstract] [Full Text] [Related]

  • 3. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
    [Abstract] [Full Text] [Related]

  • 4. The extent of dichloroacetate formation from trichloroethylene, chloral hydrate, trichloroacetate, and trichloroethanol in B6C3F1 mice.
    Merdink JL, Gonzalez-Leon A, Bull RJ, Schultz IR.
    Toxicol Sci; 1998 Sep; 45(1):33-41. PubMed ID: 9848108
    [Abstract] [Full Text] [Related]

  • 5. Kinetics of chloral hydrate and its metabolites in male human volunteers.
    Merdink JL, Robison LM, Stevens DK, Hu M, Parker JC, Bull RJ.
    Toxicology; 2008 Mar 12; 245(1-2):130-40. PubMed ID: 18243465
    [Abstract] [Full Text] [Related]

  • 6. A species comparison of chloral hydrate metabolism in blood and liver.
    Lipscomb JC, Mahle DA, Brashear WT, Garrett CM.
    Biochem Biophys Res Commun; 1996 Oct 14; 227(2):340-50. PubMed ID: 8878519
    [Abstract] [Full Text] [Related]

  • 7. Physiologically based pharmacokinetic modeling of inhaled trichloroethylene and its oxidative metabolites in B6C3F1 mice.
    Greenberg MS, Burton GA, Fisher JW.
    Toxicol Appl Pharmacol; 1999 Feb 01; 154(3):264-78. PubMed ID: 9931286
    [Abstract] [Full Text] [Related]

  • 8. Relative formation of dichloroacetate and trichloroacetate from trichloroethylene in male B6C3F1 mice.
    Templin MV, Parker JC, Bull RJ.
    Toxicol Appl Pharmacol; 1993 Nov 01; 123(1):1-8. PubMed ID: 8236248
    [Abstract] [Full Text] [Related]

  • 9. [The relative bioavailability and pharmacokinetics of chloral hydrate and its metabolites].
    Zimmermann T, Wehling M, Schulz HU.
    Arzneimittelforschung; 1998 Jan 01; 48(1):5-12. PubMed ID: 9522024
    [Abstract] [Full Text] [Related]

  • 10. Effect of enterohepatic circulation on the pharmacokinetics of chloral hydrate and its metabolites in F344 rats.
    Merdink JL, Stenner RD, Stevens DK, Parker JC, Bull RJ.
    J Toxicol Environ Health A; 1999 Jul 09; 57(5):357-68. PubMed ID: 10405189
    [Abstract] [Full Text] [Related]

  • 11. Interactions in the tumor-promoting activity of carbon tetrachloride, trichloroacetate, and dichloroacetate in the liver of male B6C3F1 mice.
    Bull RJ, Sasser LB, Lei XC.
    Toxicology; 2004 Jul 01; 199(2-3):169-83. PubMed ID: 15147791
    [Abstract] [Full Text] [Related]

  • 12. Mouse liver microsomal metabolism of chloral hydrate, trichloroacetic acid, and trichloroethanol leading to induction of lipid peroxidation via a free radical mechanism.
    Ni YC, Wong TY, Lloyd RV, Heinze TM, Shelton S, Casciano D, Kadlubar FF, Fu PP.
    Drug Metab Dispos; 1996 Jan 01; 24(1):81-90. PubMed ID: 8825194
    [Abstract] [Full Text] [Related]

  • 13. Conversion of trichloroacetic acid to dichloroacetic acid in biological samples.
    Ketcha MM, Stevens DK, Warren DA, Bishop CT, Brashear WT.
    J Anal Toxicol; 1996 Jan 01; 20(4):236-41. PubMed ID: 8835661
    [Abstract] [Full Text] [Related]

  • 14. Dichloroacetate and trichloroacetate promote clonal expansion of anchorage-independent hepatocytes in vivo and in vitro.
    Stauber AJ, Bull RJ, Thrall BD.
    Toxicol Appl Pharmacol; 1998 Jun 01; 150(2):287-94. PubMed ID: 9653059
    [Abstract] [Full Text] [Related]

  • 15. Kinetics and metabolism of chloral hydrate in children: identification of dichloroacetate as a metabolite.
    Henderson GN, Yan Z, James MO, Davydova N, Stacpoole PW.
    Biochem Biophys Res Commun; 1997 Jun 27; 235(3):695-8. PubMed ID: 9207222
    [Abstract] [Full Text] [Related]

  • 16. Species differences in the metabolism of trichloroethylene to the carcinogenic metabolites trichloroacetate and dichloroacetate.
    Larson JL, Bull RJ.
    Toxicol Appl Pharmacol; 1992 Aug 27; 115(2):278-85. PubMed ID: 1641861
    [Abstract] [Full Text] [Related]

  • 17. Differences in phenotype and cell replicative behavior of hepatic tumors induced by dichloroacetate (DCA) and trichloroacetate (TCA).
    Stauber AJ, Bull RJ.
    Toxicol Appl Pharmacol; 1997 Jun 27; 144(2):235-46. PubMed ID: 9194407
    [Abstract] [Full Text] [Related]

  • 18. Metabolism of chloral hydrate in mice and rats after single and multiple doses.
    Beland FA, Schmitt TC, Fullerton NF, Young JF.
    J Toxicol Environ Health A; 1998 Jun 12; 54(3):209-26. PubMed ID: 9643873
    [Abstract] [Full Text] [Related]

  • 19. Metabolism of bromodichloroacetate in B6C3F1 mice.
    Xu G, Stevens DK, Bull RJ.
    Drug Metab Dispos; 1995 Dec 12; 23(12):1412-6. PubMed ID: 8689953
    [Abstract] [Full Text] [Related]

  • 20. Toxicokinetics of chloral hydrate in ad libitum-fed, dietary-controlled, and calorically restricted male B6C3F1 mice following short-term exposure.
    Seng JE, Agrawal N, Horsley ET, Leakey TI, Scherer EM, Xia S, Allaben WT, Leakey JE.
    Toxicol Appl Pharmacol; 2003 Dec 01; 193(2):281-92. PubMed ID: 14644628
    [Abstract] [Full Text] [Related]

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