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215 related items for PubMed ID: 8972205

  • 1. Specific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways.
    McIlroy J, Chen D, Wjasow C, Michaeli T, Backer JM.
    Mol Cell Biol; 1997 Jan; 17(1):248-55. PubMed ID: 8972205
    [Abstract] [Full Text] [Related]

  • 2. Interactive roles of Ras, insulin receptor substrate-1, and proteins with Src homology-2 domains in insulin signaling in Xenopus oocytes.
    Chuang LM, Hausdorff SF, Myers MG, White MF, Birnbaum MJ, Kahn CR.
    J Biol Chem; 1994 Nov 04; 269(44):27645-9. PubMed ID: 7961682
    [Abstract] [Full Text] [Related]

  • 3. Activation of phosphatidylinositol 3-kinase, protein kinase B, and p70 S6 kinases in lipopolysaccharide-stimulated Raw 264.7 cells: differential effects of rapamycin, Ly294002, and wortmannin on nitric oxide production.
    Salh B, Wagey R, Marotta A, Tao JS, Pelech S.
    J Immunol; 1998 Dec 15; 161(12):6947-54. PubMed ID: 9862729
    [Abstract] [Full Text] [Related]

  • 4. A regulatory role for cAMP in phosphatidylinositol 3-kinase/p70 ribosomal S6 kinase-mediated DNA synthesis in platelet-derived-growth-factor-stimulated bovine airway smooth-muscle cells.
    Scott PH, Belham CM, al-Hafidh J, Chilvers ER, Peacock AJ, Gould GW, Plevin R.
    Biochem J; 1996 Sep 15; 318 ( Pt 3)(Pt 3):965-71. PubMed ID: 8836145
    [Abstract] [Full Text] [Related]

  • 5. Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase.
    Shepherd PR, Navé BT, Siddle K.
    Biochem J; 1995 Jan 01; 305 ( Pt 1)(Pt 1):25-8. PubMed ID: 7826337
    [Abstract] [Full Text] [Related]

  • 6. Normal activation of p70 S6 kinase by insulin in cells overexpressing dominant negative 85kD subunit of phosphoinositide 3-kinase.
    Hara K, Yonezawa K, Sakaue H, Kotani K, Kotani K, Kojima A, Waterfield MD, Kasuga M.
    Biochem Biophys Res Commun; 1995 Mar 17; 208(2):735-41. PubMed ID: 7695630
    [Abstract] [Full Text] [Related]

  • 7. Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts.
    Takuwa N, Fukui Y, Takuwa Y.
    Mol Cell Biol; 1999 Feb 17; 19(2):1346-58. PubMed ID: 9891068
    [Abstract] [Full Text] [Related]

  • 8. The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways.
    Coolican SA, Samuel DS, Ewton DZ, McWade FJ, Florini JR.
    J Biol Chem; 1997 Mar 07; 272(10):6653-62. PubMed ID: 9045696
    [Abstract] [Full Text] [Related]

  • 9. Temporal activation of p70 S6 kinase and Akt1 by insulin: PI 3-kinase-dependent and -independent mechanisms.
    Somwar R, Sumitani S, Taha C, Sweeney G, Klip A.
    Am J Physiol; 1998 Oct 07; 275(4):E618-25. PubMed ID: 9755080
    [Abstract] [Full Text] [Related]

  • 10. ATP-dependent choline phosphate-induced mitogenesis in fibroblasts involves activation of pp70 S6 kinase and phosphatidylinositol 3'-kinase through an extracellular site. Synergistic mitogenic effects of choline phosphate and sphingosine 1-phosphate.
    Chung T, Crilly KS, Anderson WH, Mukherjee JJ, Kiss Z.
    J Biol Chem; 1997 Jan 31; 272(5):3064-72. PubMed ID: 9006957
    [Abstract] [Full Text] [Related]

  • 11. Ras-independent and wortmannin-sensitive activation of glycogen synthase by insulin in Chinese hamster ovary cells.
    Sakaue H, Hara K, Noguchi T, Matozaki T, Kotani K, Ogawa W, Yonezawa K, Waterfield MD, Kasuga M.
    J Biol Chem; 1995 May 12; 270(19):11304-9. PubMed ID: 7744767
    [Abstract] [Full Text] [Related]

  • 12. Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism.
    Hara K, Yonezawa K, Weng QP, Kozlowski MT, Belham C, Avruch J.
    J Biol Chem; 1998 Jun 05; 273(23):14484-94. PubMed ID: 9603962
    [Abstract] [Full Text] [Related]

  • 13. EGF-induced activation of 70-kDa S6 kinase in CHO cells expressing human EGF receptors.
    Kido Y, Okabayashi Y, Okutani T, Sugimoto Y, Sakaguchi K, Kasuga M.
    Biochem Biophys Res Commun; 1995 Apr 06; 209(1):131-8. PubMed ID: 7726827
    [Abstract] [Full Text] [Related]

  • 14. Alpha1 adrenergic receptors activate phosphatidylinositol 3-kinase in human vascular smooth muscle cells. Role in mitogenesis.
    Hu ZW, Shi XY, Lin RZ, Hoffman BB.
    J Biol Chem; 1996 Apr 12; 271(15):8977-82. PubMed ID: 8621543
    [Abstract] [Full Text] [Related]

  • 15. Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways.
    Klippel A, Reinhard C, Kavanaugh WM, Apell G, Escobedo MA, Williams LT.
    Mol Cell Biol; 1996 Aug 12; 16(8):4117-27. PubMed ID: 8754810
    [Abstract] [Full Text] [Related]

  • 16. Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression.
    Jhun BH, Rose DW, Seely BL, Rameh L, Cantley L, Saltiel AR, Olefsky JM.
    Mol Cell Biol; 1994 Nov 12; 14(11):7466-75. PubMed ID: 7935461
    [Abstract] [Full Text] [Related]

  • 17. Functional interactions of phosphatidylinositol 3-kinase with GTPase-activating protein in 3T3-L1 adipocytes.
    DePaolo D, Reusch JE, Carel K, Bhuripanyo P, Leitner JW, Draznin B.
    Mol Cell Biol; 1996 Apr 12; 16(4):1450-7. PubMed ID: 8657118
    [Abstract] [Full Text] [Related]

  • 18. Signaling pathway involved in the activation of heart 6-phosphofructo-2-kinase by insulin.
    Lefebvre V, Méchin MC, Louckx MP, Rider MH, Hue L.
    J Biol Chem; 1996 Sep 13; 271(37):22289-92. PubMed ID: 8798384
    [Abstract] [Full Text] [Related]

  • 19. Phosphatidylinositol 3'-kinase, but not p70 ribosomal S6 kinase, is involved in membrane protein recycling: wortmannin inhibits glucose transport and downregulates cell-surface transferrin receptor numbers independently of any effect on fluid-phase endocytosis in fibroblasts.
    Jess TJ, Belham CM, Thomson FJ, Scott PH, Plevin RJ, Gould GW.
    Cell Signal; 1996 Jun 13; 8(4):297-304. PubMed ID: 8842531
    [Abstract] [Full Text] [Related]

  • 20. Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase.
    Tsakiridis T, Taha C, Grinstein S, Klip A.
    J Biol Chem; 1996 Aug 16; 271(33):19664-7. PubMed ID: 8702668
    [Abstract] [Full Text] [Related]

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