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105 related items for PubMed ID: 8975787
1. The role of hydrolysis in the detoxification of 1,2:3,4-diepoxybutane by human, rat, and mouse liver and lung in vitro. Boogaard PJ, Bond JA. Toxicol Appl Pharmacol; 1996 Dec; 141(2):617-27. PubMed ID: 8975787 [Abstract] [Full Text] [Related]
2. Glutathione conjugation of 1,2:3,4- diepoxybutane in human liver and rat and mouse liver and lung in vitro. Boogaard PJ, Sumner SC, Bond JA. Toxicol Appl Pharmacol; 1996 Feb; 136(2):307-16. PubMed ID: 8619238 [Abstract] [Full Text] [Related]
3. Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats and mice. Csanády GA, Guengerich FP, Bond JA. Carcinogenesis; 1992 Jul; 13(7):1143-53. PubMed ID: 1638680 [Abstract] [Full Text] [Related]
4. Hepatic and pulmonary glutathione conjugation of 1,2:3,4-diepoxybutane in human, rat, and mouse in vitro. Boogaard PJ, Sumner SC, Turner MJ, Bond JA. Toxicology; 1996 Oct 28; 113(1-3):297-9. PubMed ID: 8901912 [Abstract] [Full Text] [Related]
5. Oxidation of 1,2-epoxy-3-butene to 1,2:3,4-diepoxybutane by cDNA-expressed human cytochromes P450 2E1 and 3A4 and human, mouse and rat liver microsomes. Seaton MJ, Follansbee MH, Bond JA. Carcinogenesis; 1995 Oct 28; 16(10):2287-93. PubMed ID: 7586124 [Abstract] [Full Text] [Related]
9. In vivo doses of butadiene epoxides as estimated from in vitro enzyme kinetics by using cob(I)alamin and measured hemoglobin adducts: an inter-species extrapolation approach. Motwani HV, Törnqvist M. Toxicol Appl Pharmacol; 2014 Dec 15; 281(3):276-84. PubMed ID: 25448046 [Abstract] [Full Text] [Related]
10. In vitro metabolism of 4-vinylcyclohexene in rat and mouse liver, lung, and ovary. Keller DA, Carpenter SC, Cagen SZ, Reitman FA. Toxicol Appl Pharmacol; 1997 May 15; 144(1):36-44. PubMed ID: 9169067 [Abstract] [Full Text] [Related]
11. Characterization of urinary metabolites from Sprague-Dawley rats and B6C3F1 mice exposed to [1,2,3,4-13C]butadiene. Nauhaus SK, Fennell TR, Asgharian B, Bond JA, Sumner SC. Chem Res Toxicol; 1996 Jun 15; 9(4):764-73. PubMed ID: 8831821 [Abstract] [Full Text] [Related]
12. High concentrations of butadiene epoxides in livers and lungs of mice compared to rats exposed to 1,3-butadiene. Himmelstein MW, Asgharian B, Bond JA. Toxicol Appl Pharmacol; 1995 Jun 15; 132(2):281-8. PubMed ID: 7785055 [Abstract] [Full Text] [Related]
13. Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation. Himmelstein MW, Turner MJ, Asgharian B, Bond JA. Carcinogenesis; 1994 Aug 15; 15(8):1479-86. PubMed ID: 8055623 [Abstract] [Full Text] [Related]
14. Identification of novel metabolites of butadiene monoepoxide in rats and mice. Richardson KA, Peters MM, Megens RH, van Elburg PA, Golding BT, Boogaard PJ, Watson WP, van Sittert NJ. Chem Res Toxicol; 1998 Dec 15; 11(12):1543-55. PubMed ID: 9860500 [Abstract] [Full Text] [Related]
15. A physiologically based pharmacokinetic model for butadiene and its metabolite butadiene monoxide in rat and mouse and its significance for risk extrapolation. Johanson G, Filser JG. Arch Toxicol; 1993 Dec 15; 67(3):151-63. PubMed ID: 8494494 [Abstract] [Full Text] [Related]
16. Cellular and molecular basis for species, sex and tissue differences in 1,3-butadiene metabolism. Elfarra AA, Krause RJ, Kemper RA. Chem Biol Interact; 2001 Jun 01; 135-136():239-48. PubMed ID: 11397394 [Abstract] [Full Text] [Related]
17. Metabolism of butadiene monoxide by freshly isolated hepatocytes from mice and rats: different partitioning between oxidative, hydrolytic, and conjugation pathways. Kemper RA, Krause RJ, Elfarra AA. Drug Metab Dispos; 2001 Jun 01; 29(6):830-6. PubMed ID: 11353751 [Abstract] [Full Text] [Related]
18. Epidemiological and mechanistic data suggest that 1,3-butadiene will not be carcinogenic to humans at exposures likely to be encountered in the environment or workplace. Bond JA, Recio L, Andjelkovich D. Carcinogenesis; 1995 Feb 01; 16(2):165-71. PubMed ID: 7859344 [Abstract] [Full Text] [Related]
19. Species and tissue differences in the microsomal oxidation of 1,3-butadiene and the glutathione conjugation of butadiene monoxide in mice and rats. Possible role in 1,3-butadiene-induced toxicity. Sharer JE, Duescher RJ, Elfarra AA. Drug Metab Dispos; 1992 Feb 01; 20(5):658-64. PubMed ID: 1358569 [Abstract] [Full Text] [Related]
20. Metabolism of 1,3-butadiene: inhalation pharmacokinetics and tissue dosimetry of butadiene epoxides in rats and mice. Himmelstein MW, Turner MJ, Asgharian B, Bond JA. Toxicology; 1996 Oct 28; 113(1-3):306-9. PubMed ID: 8901914 [Abstract] [Full Text] [Related] Page: [Next] [New Search]