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Journal Abstract Search

336 related items for PubMed ID: 8986606

  • 1. The PML and PML/RARalpha domains: from autoimmunity to molecular oncology and from retinoic acid to arsenic.
    Andre C, Guillemin MC, Zhu J, Koken MH, Quignon F, Herve L, Chelbi-Alix MK, Dhumeaux D, Wang ZY, Degos L, Chen Z, de The H.
    Exp Cell Res; 1996 Dec 15; 229(2):253-60. PubMed ID: 8986606
    [Abstract] [Full Text] [Related]

  • 2. PIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemia.
    Sternsdorf T, Puccetti E, Jensen K, Hoelzer D, Will H, Ottmann OG, Ruthardt M.
    Mol Cell Biol; 1999 Jul 15; 19(7):5170-8. PubMed ID: 10373566
    [Abstract] [Full Text] [Related]

  • 3. Retinoic acid, but not arsenic trioxide, degrades the PLZF/RARalpha fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17)(q23;q21) APL patient.
    Koken MH, Daniel MT, Gianni M, Zelent A, Licht J, Buzyn A, Minard P, Degos L, Varet B, de Thé H.
    Oncogene; 1999 Jan 28; 18(4):1113-8. PubMed ID: 10023688
    [Abstract] [Full Text] [Related]

  • 4. Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins.
    Rego EM, He LZ, Warrell RP, Wang ZG, Pandolfi PP.
    Proc Natl Acad Sci U S A; 2000 Aug 29; 97(18):10173-8. PubMed ID: 10954752
    [Abstract] [Full Text] [Related]

  • 5. Methylated arsenic metabolites bind to PML protein but do not induce cellular differentiation and PML-RARα protein degradation.
    Wang QQ, Zhou XY, Zhang YF, Bu N, Zhou J, Cao FL, Naranmandura H.
    Oncotarget; 2015 Sep 22; 6(28):25646-59. PubMed ID: 26213848
    [Abstract] [Full Text] [Related]

  • 6. Arsenic trioxide and melarsoprol induce programmed cell death in myeloid leukemia cell lines and function in a PML and PML-RARalpha independent manner.
    Wang ZG, Rivi R, Delva L, König A, Scheinberg DA, Gambacorti-Passerini C, Gabrilove JL, Warrell RP, Pandolfi PP.
    Blood; 1998 Sep 01; 92(5):1497-504. PubMed ID: 9716575
    [Abstract] [Full Text] [Related]

  • 7. Understanding the molecular pathogenesis of acute promyelocytic leukemia.
    Lo-Coco F, Hasan SK.
    Best Pract Res Clin Haematol; 2014 Mar 01; 27(1):3-9. PubMed ID: 24907012
    [Abstract] [Full Text] [Related]

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  • 9. Arsenic but not all-trans retinoic acid overcomes the aberrant stem cell capacity of PML/RARalpha-positive leukemic stem cells.
    Zheng X, Seshire A, Rüster B, Bug G, Beissert T, Puccetti E, Hoelzer D, Henschler R, Ruthardt M.
    Haematologica; 2007 Mar 01; 92(3):323-31. PubMed ID: 17339181
    [Abstract] [Full Text] [Related]

  • 10. Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation.
    Lallemand-Breitenbach V, Zhu J, Puvion F, Koken M, Honoré N, Doubeikovsky A, Duprez E, Pandolfi PP, Puvion E, Freemont P, de Thé H.
    J Exp Med; 2001 Jun 18; 193(12):1361-71. PubMed ID: 11413191
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  • 12. Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML.
    Zhang XW, Yan XJ, Zhou ZR, Yang FF, Wu ZY, Sun HB, Liang WX, Song AX, Lallemand-Breitenbach V, Jeanne M, Zhang QY, Yang HY, Huang QH, Zhou GB, Tong JH, Zhang Y, Wu JH, Hu HY, de Thé H, Chen SJ, Chen Z.
    Science; 2010 Apr 09; 328(5975):240-3. PubMed ID: 20378816
    [Abstract] [Full Text] [Related]

  • 13. In acute promyelocytic leukemia NB4 cells, the synthetic retinoid CD437 induces contemporaneously apoptosis, a caspase-3-mediated degradation of PML/RARalpha protein and the PML retargeting on PML-nuclear bodies.
    Giannì M, de Thé H.
    Leukemia; 1999 May 09; 13(5):739-49. PubMed ID: 10374879
    [Abstract] [Full Text] [Related]

  • 14. Targeting of PML/RARalpha is lethal to retinoic acid-resistant promyelocytic leukemia cells.
    Nason-Burchenal K, Allopenna J, Bègue A, Stéhelin D, Dmitrovsky E, Martin P.
    Blood; 1998 Sep 01; 92(5):1758-67. PubMed ID: 9716606
    [Abstract] [Full Text] [Related]

  • 15. The PML-RARalpha fusion protein and targeted therapy for acute promyelocytic leukemia.
    Jing Y.
    Leuk Lymphoma; 2004 Apr 01; 45(4):639-48. PubMed ID: 15160934
    [Abstract] [Full Text] [Related]

  • 16. Novel treatment of acute promyelocytic leukemia: As₂O₃, retinoic acid and retinoid pharmacology.
    Zhu G.
    Curr Pharm Biotechnol; 2013 Apr 01; 14(9):849-58. PubMed ID: 24433507
    [Abstract] [Full Text] [Related]

  • 17. Hypoxia-simulating agents and selective stimulation of arsenic trioxide-induced growth arrest and cell differentiation in acute promyelocytic leukemic cells.
    Yan H, Peng ZG, Wu YL, Jiang Y, Yu Y, Huang Y, Zhu YS, Zhao Q, Chen GQ.
    Haematologica; 2005 Dec 01; 90(12):1607-16. PubMed ID: 16330433
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  • 19. Pathways of retinoic acid- or arsenic trioxide-induced PML/RARalpha catabolism, role of oncogene degradation in disease remission.
    Zhu J, Lallemand-Breitenbach V, de Thé H.
    Oncogene; 2001 Oct 29; 20(49):7257-65. PubMed ID: 11704854
    [Abstract] [Full Text] [Related]

  • 20. In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins.
    Chen GQ, Zhu J, Shi XG, Ni JH, Zhong HJ, Si GY, Jin XL, Tang W, Li XS, Xong SM, Shen ZX, Sun GL, Ma J, Zhang P, Zhang TD, Gazin C, Naoe T, Chen SJ, Wang ZY, Chen Z.
    Blood; 1996 Aug 01; 88(3):1052-61. PubMed ID: 8704214
    [Abstract] [Full Text] [Related]

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