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Journal Abstract Search

203 related items for PubMed ID: 8995368

  • 1. Identification of candidate active site residues in lysosomal beta-hexosaminidase A.
    Fernandes MJ, Yew S, Leclerc D, Henrissat B, Vorgias CE, Gravel RA, Hechtman P, Kaplan F.
    J Biol Chem; 1997 Jan 10; 272(2):814-20. PubMed ID: 8995368
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  • 2. Identification of an active acidic residue in the catalytic site of beta-hexosaminidase.
    Tse R, Vavougios G, Hou Y, Mahuran DJ.
    Biochemistry; 1996 Jun 11; 35(23):7599-607. PubMed ID: 8652542
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  • 11. Inefficiency in GM2 ganglioside elimination by human lysosomal beta-hexosaminidase beta-subunit gene transfer to fibroblastic cell line derived from Sandhoff disease model mice.
    Itakura T, Kuroki A, Ishibashi Y, Tsuji D, Kawashita E, Higashine Y, Sakuraba H, Yamanaka S, Itoh K.
    Biol Pharm Bull; 2006 Aug 11; 29(8):1564-9. PubMed ID: 16880605
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  • 13. Production of recombinant beta-hexosaminidase A, a potential enzyme for replacement therapy for Tay-Sachs and Sandhoff diseases, in the methylotrophic yeast Ogataea minuta.
    Akeboshi H, Chiba Y, Kasahara Y, Takashiba M, Takaoka Y, Ohsawa M, Tajima Y, Kawashima I, Tsuji D, Itoh K, Sakuraba H, Jigami Y.
    Appl Environ Microbiol; 2007 Aug 11; 73(15):4805-12. PubMed ID: 17557860
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  • 14. Identification of the 6-sulfate binding site unique to alpha-subunit-containing isozymes of human beta-hexosaminidase.
    Sharma R, Deng H, Leung A, Mahuran D.
    Biochemistry; 2001 May 08; 40(18):5440-6. PubMed ID: 11331008
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  • 15. Restoration of hexosaminidase A activity in human Tay-Sachs fibroblasts via adenoviral vector-mediated gene transfer.
    Akli S, Guidotti JE, Vigne E, Perricaudet M, Sandhoff K, Kahn A, Poenaru L.
    Gene Ther; 1996 Sep 08; 3(9):769-74. PubMed ID: 8875224
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  • 16. GM2 gangliosidosis B1 variant: biochemical and molecular characterization of hexosaminidase A.
    Peleg L, Meltzer F, Karpati M, Goldman B.
    Biochem Mol Med; 1995 Apr 08; 54(2):126-32. PubMed ID: 8581357
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  • 17. Physiological substrates for human lysosomal beta -hexosaminidase S.
    Hepbildikler ST, Sandhoff R, Kolzer M, Proia RL, Sandhoff K.
    J Biol Chem; 2002 Jan 25; 277(4):2562-72. PubMed ID: 11707436
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  • 18. A single site in human beta-hexosaminidase A binds both 6-sulfate-groups on hexosamines and the sialic acid moiety of GM2 ganglioside.
    Sharma R, Bukovac S, Callahan J, Mahuran D.
    Biochim Biophys Acta; 2003 Jan 20; 1637(1):113-8. PubMed ID: 12527415
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  • 19. Synthesis of 4-methylumbelliferyl-beta-D-N-acetylglucosamine-6-sulfate and its use in classification of GM2 gangliosidosis genotypes.
    Bayleran J, Hechtman P, Saray W.
    Clin Chim Acta; 1984 Nov 15; 143(2):73-89. PubMed ID: 6239713
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  • 20. Isolation of cDNA clones coding for the alpha-subunit of human beta-hexosaminidase. Extensive homology between the alpha- and beta-subunits and studies on Tay-Sachs disease.
    Korneluk RG, Mahuran DJ, Neote K, Klavins MH, O'Dowd BF, Tropak M, Willard HF, Anderson MJ, Lowden JA, Gravel RA.
    J Biol Chem; 1986 Jun 25; 261(18):8407-13. PubMed ID: 3013851
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