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240 related items for PubMed ID: 8995434

  • 1. A model for the double-stranded RNA (dsRNA)-dependent dimerization and activation of the dsRNA-activated protein kinase PKR.
    Wu S, Kaufman RJ.
    J Biol Chem; 1997 Jan 10; 272(2):1291-6. PubMed ID: 8995434
    [Abstract] [Full Text] [Related]

  • 2. Double-stranded (ds) RNA binding and not dimerization correlates with the activation of the dsRNA-dependent protein kinase (PKR).
    Wu S, Kaufman RJ.
    J Biol Chem; 1996 Jan 19; 271(3):1756-63. PubMed ID: 8576179
    [Abstract] [Full Text] [Related]

  • 3. trans-Autophosphorylation by the isolated kinase domain is not sufficient for dimerization or activation of the dsRNA-activated protein kinase PKR.
    Wu S, Kaufman RJ.
    Biochemistry; 2004 Aug 31; 43(34):11027-34. PubMed ID: 15323561
    [Abstract] [Full Text] [Related]

  • 4. Double-stranded RNA-activated protein kinase (PKR) is negatively regulated by 60S ribosomal subunit protein L18.
    Kumar KU, Srivastava SP, Kaufman RJ.
    Mol Cell Biol; 1999 Feb 31; 19(2):1116-25. PubMed ID: 9891046
    [Abstract] [Full Text] [Related]

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  • 6. Activation of the double-stranded RNA (dsRNA)-activated human protein kinase in vivo in the absence of its dsRNA binding domain.
    Lee SB, Green SR, Mathews MB, Esteban M.
    Proc Natl Acad Sci U S A; 1994 Oct 25; 91(22):10551-5. PubMed ID: 7937992
    [Abstract] [Full Text] [Related]

  • 7. Identification and requirement of three ribosome binding domains in dsRNA-dependent protein kinase (PKR).
    Wu S, Kumar KU, Kaufman RJ.
    Biochemistry; 1998 Sep 29; 37(39):13816-26. PubMed ID: 9753471
    [Abstract] [Full Text] [Related]

  • 8. Specific mutations near the amino terminus of double-stranded RNA-dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization properties.
    Patel RC, Stanton P, Sen GC.
    J Biol Chem; 1996 Oct 11; 271(41):25657-63. PubMed ID: 8810342
    [Abstract] [Full Text] [Related]

  • 9. The regulation of the protein kinase PKR by RNA.
    Robertson HD, Mathews MB.
    Biochimie; 1996 Oct 11; 78(11-12):909-14. PubMed ID: 9150867
    [Abstract] [Full Text] [Related]

  • 10. Heterologous dimerization domains functionally substitute for the double-stranded RNA binding domains of the kinase PKR.
    Ung TL, Cao C, Lu J, Ozato K, Dever TE.
    EMBO J; 2001 Jul 16; 20(14):3728-37. PubMed ID: 11447114
    [Abstract] [Full Text] [Related]

  • 11. Activation of PKR: an open and shut case?
    Cole JL.
    Trends Biochem Sci; 2007 Feb 16; 32(2):57-62. PubMed ID: 17196820
    [Abstract] [Full Text] [Related]

  • 12. Requirement of PKR dimerization mediated by specific hydrophobic residues for its activation by double-stranded RNA and its antigrowth effects in yeast.
    Patel RC, Sen GC.
    Mol Cell Biol; 1998 Dec 16; 18(12):7009-19. PubMed ID: 9819388
    [Abstract] [Full Text] [Related]

  • 13. Calcium depletion from the endoplasmic reticulum activates the double-stranded RNA-dependent protein kinase (PKR) to inhibit protein synthesis.
    Srivastava SP, Davies MV, Kaufman RJ.
    J Biol Chem; 1995 Jul 14; 270(28):16619-24. PubMed ID: 7622470
    [Abstract] [Full Text] [Related]

  • 14. Mechanism of activation of the double-stranded-RNA-dependent protein kinase, PKR: role of dimerization and cellular localization in the stimulation of PKR phosphorylation of eukaryotic initiation factor-2 (eIF2).
    Vattem KM, Staschke KA, Wek RC.
    Eur J Biochem; 2001 Jul 14; 268(13):3674-84. PubMed ID: 11432733
    [Abstract] [Full Text] [Related]

  • 15. Activation of PKR by short stem-loop RNAs containing single-stranded arms.
    Mayo CB, Wong CJ, Lopez PE, Lary JW, Cole JL.
    RNA; 2016 Jul 14; 22(7):1065-75. PubMed ID: 27208315
    [Abstract] [Full Text] [Related]

  • 16. Characterization of the heparin-mediated activation of PKR, the interferon-inducible RNA-dependent protein kinase.
    George CX, Thomis DC, McCormack SJ, Svahn CM, Samuel CE.
    Virology; 1996 Jul 01; 221(1):180-8. PubMed ID: 8661426
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: role of complex formation and the E3 N-terminal domain.
    Romano PR, Zhang F, Tan SL, Garcia-Barrio MT, Katze MG, Dever TE, Hinnebusch AG.
    Mol Cell Biol; 1998 Dec 01; 18(12):7304-16. PubMed ID: 9819417
    [Abstract] [Full Text] [Related]

  • 18. Biophysical and biochemical investigations of dsRNA-activated kinase PKR.
    McKenna SA, Lindhout DA, Shimoike T, Puglisi JD.
    Methods Enzymol; 2007 Dec 01; 430():373-96. PubMed ID: 17913645
    [Abstract] [Full Text] [Related]

  • 19. Mechanism of interferon action. Biochemical and genetic evidence for the intermolecular association of the RNA-dependent protein kinase PKR from human cells.
    Ortega LG, McCotter MD, Henry GL, McCormack SJ, Thomis DC, Samuel CE.
    Virology; 1996 Jan 01; 215(1):31-9. PubMed ID: 8553584
    [Abstract] [Full Text] [Related]

  • 20. Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae.
    Romano PR, Green SR, Barber GN, Mathews MB, Hinnebusch AG.
    Mol Cell Biol; 1995 Jan 01; 15(1):365-78. PubMed ID: 7799945
    [Abstract] [Full Text] [Related]

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