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524 related items for PubMed ID: 9000565

  • 1. Evidence for an important role of DNA pyridyloxobutylation in rat lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: effects of dose and phenethyl isothiocyanate.
    Staretz ME, Foiles PG, Miglietta LM, Hecht SS.
    Cancer Res; 1997 Jan 15; 57(2):259-66. PubMed ID: 9000565
    [Abstract] [Full Text] [Related]

  • 2. Complete inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced rat lung tumorigenesis and favorable modification of biomarkers by phenethyl isothiocyanate.
    Hecht SS, Trushin N, Rigotty J, Carmella SG, Borukhova A, Akerkar S, Rivenson A.
    Cancer Epidemiol Biomarkers Prev; 1996 Aug 15; 5(8):645-52. PubMed ID: 8824368
    [Abstract] [Full Text] [Related]

  • 3. Effects of phenethyl isothiocyanate on the tissue distribution of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and metabolites in F344 rats.
    Staretz ME, Hecht SS.
    Cancer Res; 1995 Dec 01; 55(23):5580-8. PubMed ID: 7585638
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation and tumorigenicity in the lung of F344 rats by dietary phenethyl isothiocyanate.
    Morse MA, Wang CX, Stoner GD, Mandal S, Conran PB, Amin SG, Hecht SS, Chung FL.
    Cancer Res; 1989 Feb 01; 49(3):549-53. PubMed ID: 2910476
    [Abstract] [Full Text] [Related]

  • 5. Effects of long term dietary phenethyl isothiocyanate on the microsomal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.
    Staretz ME, Koenig LA, Hecht SS.
    Carcinogenesis; 1997 Sep 01; 18(9):1715-22. PubMed ID: 9328166
    [Abstract] [Full Text] [Related]

  • 6. Mechanisms of inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in mouse by dietary phenethyl isothiocyanate.
    Smith TJ, Guo Z, Li C, Ning SM, Thomas PE, Yang CS.
    Cancer Res; 1993 Jul 15; 53(14):3276-82. PubMed ID: 8324738
    [Abstract] [Full Text] [Related]

  • 7. Dose-response relationship between O6-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Belinsky SA, Foley JF, White CM, Anderson MW, Maronpot RR.
    Cancer Res; 1990 Jun 15; 50(12):3772-80. PubMed ID: 2340522
    [Abstract] [Full Text] [Related]

  • 8. Effects of phenethyl isothiocyanate and benzyl isothiocyanate, individually and in combination, on lung tumorigenesis induced in A/J mice by benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Hecht SS, Kenney PM, Wang M, Trushin N, Upadhyaya P.
    Cancer Lett; 2000 Mar 13; 150(1):49-56. PubMed ID: 10755386
    [Abstract] [Full Text] [Related]

  • 9. Effect of phenethyl isothiocyanate on the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured rat lung tissue.
    Doerr-O'Rourke K, Trushin N, Hecht SS, Stoner GD.
    Carcinogenesis; 1991 Jun 13; 12(6):1029-34. PubMed ID: 2044181
    [Abstract] [Full Text] [Related]

  • 10. Chemopreventive efficacy of arylalkyl isothiocyanates and N-acetylcysteine for lung tumorigenesis in Fischer rats.
    Chung FL, Kelloff G, Steele V, Pittman B, Zang E, Jiao D, Rigotty J, Choi CI, Rivenson A.
    Cancer Res; 1996 Feb 15; 56(4):772-8. PubMed ID: 8631012
    [Abstract] [Full Text] [Related]

  • 11. Formation and accumulation of pyridyloxobutyl DNA adducts in F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Lao Y, Yu N, Kassie F, Villalta PW, Hecht SS.
    Chem Res Toxicol; 2007 Feb 15; 20(2):235-45. PubMed ID: 17305407
    [Abstract] [Full Text] [Related]

  • 12. Effects of aromatic isothiocyanates on tumorigenicity, O6-methylguanine formation, and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung.
    Morse MA, Amin SG, Hecht SS, Chung FL.
    Cancer Res; 1989 Jun 01; 49(11):2894-7. PubMed ID: 2720649
    [Abstract] [Full Text] [Related]

  • 13. Effects of benzyl isothiocyanate and 2-phenethyl isothiocyanate on benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism in F-344 rats.
    Boysen G, Kenney PM, Upadhyaya P, Wang M, Hecht SS.
    Carcinogenesis; 2003 Mar 01; 24(3):517-25. PubMed ID: 12663513
    [Abstract] [Full Text] [Related]

  • 14. Formation and repair of pyridyloxobutyl DNA adducts and their relationship to tumor yield in A/J mice.
    Urban AM, Upadhyaya P, Cao Q, Peterson LA.
    Chem Res Toxicol; 2012 Oct 15; 25(10):2167-78. PubMed ID: 22928598
    [Abstract] [Full Text] [Related]

  • 15. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates.
    Smith TJ, Guo ZY, Thomas PE, Chung FL, Morse MA, Elkind K, Yang CS.
    Cancer Res; 1990 Nov 01; 50(21):6817-22. PubMed ID: 2208146
    [Abstract] [Full Text] [Related]

  • 16. Effects of benzyl isothiocyanate and phenethyl isothiocyanate on DNA adduct formation by a mixture of benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung.
    Sticha KR, Kenney PM, Boysen G, Liang H, Su X, Wang M, Upadhyaya P, Hecht SS.
    Carcinogenesis; 2002 Sep 01; 23(9):1433-9. PubMed ID: 12189184
    [Abstract] [Full Text] [Related]

  • 17. Effects of dietary 1,4-phenylenebis(methylene)selenocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation in lung and liver of A/J mice and F344 rats.
    Prokopczyk B, Cox JE, Upadhyaya P, Amin S, Desai D, Hoffmann D, el-Bayoumy K.
    Carcinogenesis; 1996 Apr 01; 17(4):749-53. PubMed ID: 8625486
    [Abstract] [Full Text] [Related]

  • 18. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice.
    Guo Z, Smith TJ, Wang E, Eklind KI, Chung FL, Yang CS.
    Carcinogenesis; 1993 Jun 01; 14(6):1167-73. PubMed ID: 8508504
    [Abstract] [Full Text] [Related]

  • 19. Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Upadhyaya P, Kalscheuer S, Hochalter JB, Villalta PW, Hecht SS.
    Chem Res Toxicol; 2008 Jul 01; 21(7):1468-76. PubMed ID: 18570389
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of tobacco-specific nitrosamine 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) tumorigenesis with aromatic isothiocyanates.
    Morse MA, Eklind KI, Hecht SS, Chung FL.
    IARC Sci Publ; 1991 Jul 01; (105):529-34. PubMed ID: 1855911
    [Abstract] [Full Text] [Related]

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