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3. The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation. Iwamoto T, Senga T, Naito Y, Matsuda S, Miyake Y, Yoshimura A, Hamaguchi M. Oncogene; 2000 Sep 28; 19(41):4795-801. PubMed ID: 11032030 [Abstract] [Full Text] [Related]
4. The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH. Smit LS, Meyer DJ, Billestrup N, Norstedt G, Schwartz J, Carter-Su C. Mol Endocrinol; 1996 May 28; 10(5):519-33. PubMed ID: 8732683 [Abstract] [Full Text] [Related]
6. Platelet-derived growth factor (PDGF)-induced activation of signal transducer and activator of transcription (Stat) 5 is mediated by PDGF beta-receptor and is not dependent on c-src, fyn, jak1 or jak2 kinases. Paukku K, Valgeirsdóttir S, Saharinen P, Bergman M, Heldin CH, Silvennoinen O. Biochem J; 2000 Feb 01; 345 Pt 3(Pt 3):759-66. PubMed ID: 10642538 [Abstract] [Full Text] [Related]
7. Constitutive activation of Jak2 contributes to proliferation and resistance to apoptosis in NPM/ALK-transformed cells. Ruchatz H, Coluccia AM, Stano P, Marchesi E, Gambacorti-Passerini C. Exp Hematol; 2003 Apr 01; 31(4):309-15. PubMed ID: 12691918 [Abstract] [Full Text] [Related]
8. Differential role of Janus family kinases (JAKs) in interferon-gamma-induced lung epithelial ICAM-1 expression: involving protein interactions between JAKs, phospholipase Cgamma, c-Src, and STAT1. Chang YJ, Holtzman MJ, Chen CC. Mol Pharmacol; 2004 Mar 01; 65(3):589-98. PubMed ID: 14978237 [Abstract] [Full Text] [Related]
10. Cells transformed by ODC, c-Ha-ras and v-src exhibit MAP kinase/Erk-independent constitutive phosphorylation of Sos, Raf and c-Jun activation domain, and reduced PDGF receptor expression. Paasinen-Sohns A, Hölttä E. Oncogene; 1997 Oct 16; 15(16):1953-66. PubMed ID: 9365242 [Abstract] [Full Text] [Related]
11. Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways. Neilson LM, Zhu J, Xie J, Malabarba MG, Sakamoto K, Wagner KU, Kirken RA, Rui H. Mol Endocrinol; 2007 Sep 16; 21(9):2218-32. PubMed ID: 17550976 [Abstract] [Full Text] [Related]
12. Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice. Blaskovich MA, Sun J, Cantor A, Turkson J, Jove R, Sebti SM. Cancer Res; 2003 Mar 15; 63(6):1270-9. PubMed ID: 12649187 [Abstract] [Full Text] [Related]
13. SH2-B family members differentially regulate JAK family tyrosine kinases. O'Brien KB, O'Shea JJ, Carter-Su C. J Biol Chem; 2002 Mar 08; 277(10):8673-81. PubMed ID: 11751854 [Abstract] [Full Text] [Related]
14. Identification of SH2-bbeta as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2. Rui L, Carter-Su C. Proc Natl Acad Sci U S A; 1999 Jun 22; 96(13):7172-7. PubMed ID: 10377387 [Abstract] [Full Text] [Related]
15. Constitutive activation of Jak-2 and Tyk-2 in a v-Src-transformed human gallbladder adenocarcinoma cell line. Murakami Y, Nakano S, Niho Y, Hamasaki N, Izuhara K. J Cell Physiol; 1998 May 22; 175(2):220-8. PubMed ID: 9525481 [Abstract] [Full Text] [Related]
16. Constitutive activation of the Janus kinase-STAT pathway in T lymphoma overexpressing the Lck protein tyrosine kinase. Yu CL, Jove R, Burakoff SJ. J Immunol; 1997 Dec 01; 159(11):5206-10. PubMed ID: 9548458 [Abstract] [Full Text] [Related]
17. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression. Schaper F, Gendo C, Eck M, Schmitz J, Grimm C, Anhuf D, Kerr IM, Heinrich PC. Biochem J; 1998 Nov 01; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795 [Abstract] [Full Text] [Related]
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19. Mechanism of STAT3 activation by insulin-like growth factor I receptor. Zong CS, Chan J, Levy DE, Horvath C, Sadowski HB, Wang LH. J Biol Chem; 2000 May 19; 275(20):15099-105. PubMed ID: 10747872 [Abstract] [Full Text] [Related]
20. Activation of YRP kinase by v-Src and protein kinase C-mediated signal transduction pathways. Scholz G, Felder MP, Hanafusa H. Proc Natl Acad Sci U S A; 1995 Mar 28; 92(7):2592-6. PubMed ID: 7535926 [Abstract] [Full Text] [Related] Page: [Next] [New Search]