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Journal Abstract Search


230 related items for PubMed ID: 9010701

  • 1. Codeine and morphine in extensive and poor metabolizers of sparteine: pharmacokinetics, analgesic effect and side effects.
    Poulsen L, Brøsen K, Arendt-Nielsen L, Gram LF, Elbaek K, Sindrup SH.
    Eur J Clin Pharmacol; 1996; 51(3-4):289-95. PubMed ID: 9010701
    [Abstract] [Full Text] [Related]

  • 2. Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation.
    Eckhardt K, Li S, Ammon S, Schänzle G, Mikus G, Eichelbaum M.
    Pain; 1998 May; 76(1-2):27-33. PubMed ID: 9696456
    [Abstract] [Full Text] [Related]

  • 3. Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication.
    Kirchheiner J, Schmidt H, Tzvetkov M, Keulen JT, Lötsch J, Roots I, Brockmöller J.
    Pharmacogenomics J; 2007 Aug; 7(4):257-65. PubMed ID: 16819548
    [Abstract] [Full Text] [Related]

  • 4. Codeine increases pain thresholds to copper vapor laser stimuli in extensive but not poor metabolizers of sparteine.
    Sindrup SH, Brøsen K, Bjerring P, Arendt-Nielsen L, Larsen U, Angelo HR, Gram LF.
    Clin Pharmacol Ther; 1990 Dec; 48(6):686-93. PubMed ID: 2249379
    [Abstract] [Full Text] [Related]

  • 5. Codeine in post-operative pain. Study of the influence of sparteine phenotype and serum concentrations of morphine and morphine-6-glucuronide.
    Poulsen L, Riishede L, Brøsen K, Clemensen S, Sindrup SH.
    Eur J Clin Pharmacol; 1998 Aug; 54(6):451-4. PubMed ID: 9776433
    [Abstract] [Full Text] [Related]

  • 6. The pharmacogenetics of codeine hypoalgesia.
    Sindrup SH, Brøsen K.
    Pharmacogenetics; 1995 Dec; 5(6):335-46. PubMed ID: 8845855
    [Abstract] [Full Text] [Related]

  • 7. Are poor metabolisers of sparteine/debrisoquine less pain tolerant than extensive metabolisers?
    Sindrup SH, Poulsen L, Brøsen K, Arendt-Nielsen L, Gram LF.
    Pain; 1993 Jun; 53(3):335-339. PubMed ID: 8351162
    [Abstract] [Full Text] [Related]

  • 8. Impact of quinidine on plasma and cerebrospinal fluid concentrations of codeine and morphine after codeine intake.
    Sindrup SH, Hofmann U, Asmussen J, Mikus G, Brøsen K, Nielsen F, Ingwersen SH, Broen Christensen C.
    Eur J Clin Pharmacol; 1996 Jun; 49(6):503-9. PubMed ID: 8706777
    [Abstract] [Full Text] [Related]

  • 9. Effect of codeine on gastrointestinal motility in relation to CYP2D6 phenotype.
    Mikus G, Trausch B, Rodewald C, Hofmann U, Richter K, Gramatté T, Eichelbaum M.
    Clin Pharmacol Ther; 1997 Apr; 61(4):459-66. PubMed ID: 9129563
    [Abstract] [Full Text] [Related]

  • 10. Pharmacogenetic determinants of codeine induction by rifampin: the impact on codeine's respiratory, psychomotor and miotic effects.
    Caraco Y, Sheller J, Wood AJ.
    J Pharmacol Exp Ther; 1997 Apr; 281(1):330-6. PubMed ID: 9103514
    [Abstract] [Full Text] [Related]

  • 11. Polymorphic CYP2D6 mediates O-demethylation of the opioid analgesic tramadol.
    Paar WD, Poche S, Gerloff J, Dengler HJ.
    Eur J Clin Pharmacol; 1997 Apr; 53(3-4):235-9. PubMed ID: 9476037
    [Abstract] [Full Text] [Related]

  • 12. The effect of quinidine on the analgesic effect of codeine.
    Sindrup SH, Arendt-Nielsen L, Brøsen K, Bjerring P, Angelo HR, Eriksen B, Gram LF.
    Eur J Clin Pharmacol; 1992 Apr; 42(6):587-91. PubMed ID: 1623898
    [Abstract] [Full Text] [Related]

  • 13. Evidence for morphine-independent central nervous opioid effects after administration of codeine: contribution of other codeine metabolites.
    Lötsch J, Skarke C, Schmidt H, Rohrbacher M, Hofmann U, Schwab M, Geisslinger G.
    Clin Pharmacol Ther; 2006 Jan; 79(1):35-48. PubMed ID: 16413240
    [Abstract] [Full Text] [Related]

  • 14. Pharmacogenetic determination of the effects of codeine and prediction of drug interactions.
    Caraco Y, Sheller J, Wood AJ.
    J Pharmacol Exp Ther; 1996 Sep; 278(3):1165-74. PubMed ID: 8819499
    [Abstract] [Full Text] [Related]

  • 15. CYP2D6 polymorphisms and codeine analgesia in postpartum pain management: a pilot study.
    VanderVaart S, Berger H, Sistonen J, Madadi P, Matok I, Gijsen VM, de Wildt SN, Taddio A, Ross CJ, Carleton BC, Hayden MR, Koren G.
    Ther Drug Monit; 2011 Aug; 33(4):425-32. PubMed ID: 21743374
    [Abstract] [Full Text] [Related]

  • 16. The hypoalgesic effect of tramadol in relation to CYP2D6.
    Poulsen L, Arendt-Nielsen L, Brøsen K, Sindrup SH.
    Clin Pharmacol Ther; 1996 Dec; 60(6):636-44. PubMed ID: 8988065
    [Abstract] [Full Text] [Related]

  • 17. O-demethylation of codeine to morphine inhibited by low-dose levomepromazine.
    Vevelstad M, Pettersen S, Tallaksen C, Brørs O.
    Eur J Clin Pharmacol; 2009 Aug; 65(8):795-801. PubMed ID: 19308365
    [Abstract] [Full Text] [Related]

  • 18. The role of active metabolites in dihydrocodeine effects.
    Schmidt H, Vormfelde SV, Walchner-Bonjean M, Klinder K, Freudenthaler S, Gleiter CH, Gundert-Remy U, Skopp G, Aderjan R, Fuhr U.
    Int J Clin Pharmacol Ther; 2003 Mar; 41(3):95-106. PubMed ID: 12665158
    [Abstract] [Full Text] [Related]

  • 19. Influence of Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) polymorphisms on pain sensitivity and clinical response to weak opioid analgesics.
    Zahari Z, Ismail R.
    Drug Metab Pharmacokinet; 2014 Mar; 29(1):29-43. PubMed ID: 23759977
    [Abstract] [Full Text] [Related]

  • 20. Dihydrocodeine: a new opioid substrate for the polymorphic CYP2D6 in humans.
    Fromm MF, Hofmann U, Griese EU, Mikus G.
    Clin Pharmacol Ther; 1995 Oct; 58(4):374-82. PubMed ID: 7586928
    [Abstract] [Full Text] [Related]


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