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361 related items for PubMed ID: 9012451

  • 1. Coexpression of a multidrug resistance gene (MDR1) and herpes simplex virus thymidine kinase gene in a bicistronic retroviral vector Ha-MDR-IRES-TK allows selective killing of MDR1-transduced human tumors transplanted in nude mice.
    Sugimoto Y, Sato S, Tsukahara S, Suzuki M, Okochi E, Gottesman MM, Pastan I, Tsuruo T.
    Cancer Gene Ther; 1997; 4(1):51-8. PubMed ID: 9012451
    [Abstract] [Full Text] [Related]

  • 2. Drug-selected co-expression of P-glycoprotein and gp91 in vivo from an MDR1-bicistronic retrovirus vector Ha-MDR-IRES-gp91.
    Sugimoto Y, Tsukahara S, Sato S, Suzuki M, Nunoi H, Malech HL, Gottesman MM, Tsuruo T.
    J Gene Med; 2003 May; 5(5):366-76. PubMed ID: 12731085
    [Abstract] [Full Text] [Related]

  • 3. Coexpression of a multidrug-resistance gene (MDR1) and herpes simplex virus thymidine kinase gene as part of a bicistronic messenger RNA in a retrovirus vector allows selective killing of MDR1-transduced cells.
    Sugimoto Y, Hrycyna CA, Aksentijevich I, Pastan I, Gottesman MM.
    Clin Cancer Res; 1995 Apr; 1(4):447-57. PubMed ID: 9816003
    [Abstract] [Full Text] [Related]

  • 4. Retroviral coexpression of two different types of drug resistance genes to protect normal cells from combination chemotherapy.
    Suzuki M, Sugimoto Y, Tsukahara S, Okochi E, Gottesman MM, Tsuruo T.
    Clin Cancer Res; 1997 Jun; 3(6):947-54. PubMed ID: 9815770
    [Abstract] [Full Text] [Related]

  • 5. Enhanced tumor cell killing in the presence of ganciclovir by herpes simplex virus type 1 vector-directed coexpression of human tumor necrosis factor-alpha and herpes simplex virus thymidine kinase.
    Moriuchi S, Oligino T, Krisky D, Marconi P, Fink D, Cohen J, Glorioso JC.
    Cancer Res; 1998 Dec 15; 58(24):5731-7. PubMed ID: 9865731
    [Abstract] [Full Text] [Related]

  • 6. In situ generation of pseudotyped retroviral progeny by adenovirus-mediated transduction of tumor cells enhances the killing effect of HSV-tk suicide gene therapy in vitro and in vivo.
    Okada T, Caplen NJ, Ramsey WJ, Onodera M, Shimazaki K, Nomoto T, Ajalli R, Wildner O, Morris J, Kume A, Hamada H, Blaese RM, Ozawa K.
    J Gene Med; 2004 Mar 15; 6(3):288-99. PubMed ID: 15026990
    [Abstract] [Full Text] [Related]

  • 7. Transduction of human pancreatic tumor cells with vesicular stomatitis virus G-pseudotyped retroviral vectors containing a herpes simplex virus thymidine kinase mutant gene enhances bystander effects and sensitivity to ganciclovir.
    Howard BD, Boenicke L, Schniewind B, Henne-Bruns D, Kalthoff H.
    Cancer Gene Ther; 2000 Jun 15; 7(6):927-38. PubMed ID: 10880025
    [Abstract] [Full Text] [Related]

  • 8. [Studies on herpes simplex virus thymidine kinase gene and GCV system for treatment of human bladder carcinoma].
    He J, Chen Y, Li H, Lu Y, Yan Y, Tan X.
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi; 2004 Jun 15; 21(3):428-32. PubMed ID: 15250149
    [Abstract] [Full Text] [Related]

  • 9. Gene therapy against an experimental glioma using adeno-associated virus vectors.
    Okada H, Miyamura K, Itoh T, Hagiwara M, Wakabayashi T, Mizuno M, Colosi P, Kurtzman G, Yoshida J.
    Gene Ther; 1996 Nov 15; 3(11):957-64. PubMed ID: 8940635
    [Abstract] [Full Text] [Related]

  • 10. Purified herpes simplex virus thymidine kinase retroviral particles: III. Characterization of bystander killing mechanisms in transfected tumor cells.
    Burrows FJ, Gore M, Smiley WR, Kanemitsu MY, Jolly DJ, Read SB, Nicholas T, Kruse CA.
    Cancer Gene Ther; 2002 Jan 15; 9(1):87-95. PubMed ID: 11916247
    [Abstract] [Full Text] [Related]

  • 11. Killing effects of ganciclovir on human pulmonary adenocarcinoma cell A549 transduced with HSV1-TK gene in vitro and in vivo.
    He XL, Guo XJ, Qian GS, He XH, Huang GJ, Chen WZ, Li SP.
    Acta Pharmacol Sin; 2001 Oct 15; 22(10):901-6. PubMed ID: 11749772
    [Abstract] [Full Text] [Related]

  • 12. Mechanisms for ganciclovir resistance in gastrointestinal tumor cells transduced with a retroviral vector containing the herpes simplex virus thymidine kinase gene.
    Yang L, Hwang R, Chiang Y, Gordon EM, Anderson WF, Parekh D.
    Clin Cancer Res; 1998 Mar 15; 4(3):731-41. PubMed ID: 9533543
    [Abstract] [Full Text] [Related]

  • 13. Bystander effect caused by suicide gene expression indicates the feasibility of gene therapy for hepatocellular carcinoma.
    Kuriyama S, Nakatani T, Masui K, Sakamoto T, Tominaga K, Yoshikawa M, Fukui H, Ikenaka K, Tsujii T.
    Hepatology; 1995 Dec 15; 22(6):1838-46. PubMed ID: 7489996
    [Abstract] [Full Text] [Related]

  • 14. Adenovirus-mediated gene transfer of enhanced Herpes simplex virus thymidine kinase mutants improves prodrug-mediated tumor cell killing.
    Wiewrodt R, Amin K, Kiefer M, Jovanovic VP, Kapoor V, Force S, Chang M, Lanuti M, Black ME, Kaiser LR, Albelda SM.
    Cancer Gene Ther; 2003 May 15; 10(5):353-64. PubMed ID: 12719705
    [Abstract] [Full Text] [Related]

  • 15. HSV-tk gene therapy for human renal cell carcinoma in nude mice.
    Pulkkanen KJ, Parkkinen JJ, Laukkanen JM, Kettunen MI, Tyynela K, Kauppinen RA, Ala-Opas MY, Yla-Herttuala S.
    Cancer Gene Ther; 2001 Jul 15; 8(7):529-36. PubMed ID: 11498775
    [Abstract] [Full Text] [Related]

  • 16. Adeno-associated viral-mediated gene transfer to hepatoma: thymidine kinase/interleukin 2 is more effective in tumor killing in non-ganciclovir (GCV)-treated than in GCV-treated animals.
    Su H, Lu R, Ding R, Kan YW.
    Mol Ther; 2000 Jun 15; 1(6):509-15. PubMed ID: 10933975
    [Abstract] [Full Text] [Related]

  • 17. An experimental application of gene therapy for human retinoblastoma.
    Hayashi N, Ido E, Ohtsuki Y, Ueno H.
    Invest Ophthalmol Vis Sci; 1999 Feb 15; 40(2):265-72. PubMed ID: 9950583
    [Abstract] [Full Text] [Related]

  • 18. Herpes simplex virus thymidine kinase gene transduction enhances tumor growth rate and cyclooxygenase-2 expression in murine colon cancer cells.
    Konson A, Ben-Kasus T, Mahajna JA, Danon A, Rimon G, Agbaria R.
    Cancer Gene Ther; 2004 Dec 15; 11(12):830-40. PubMed ID: 15359292
    [Abstract] [Full Text] [Related]

  • 19. Characteristics of ovarian cancer cells transduced by the bicistronic retroviral vector containing GM-CSF and HSV-TK genes.
    Guan J, Ma L, Wei L.
    Chin Med J (Engl); 2001 Feb 15; 114(2):147-51. PubMed ID: 11780195
    [Abstract] [Full Text] [Related]

  • 20. Avoidance of bone marrow suppression using A-5021 as a nucleoside analog for retrovirus-mediated herpes simplex virus type I thymidine kinase gene therapy.
    Hasegawa Y, Nishiyama Y, Imaizumi K, Ono N, Kinoshita T, Hatano S, Saito H, Shimokata K.
    Cancer Gene Ther; 2000 Apr 15; 7(4):557-62. PubMed ID: 10811473
    [Abstract] [Full Text] [Related]

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