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Journal Abstract Search

172 related items for PubMed ID: 9012519

  • 1. The human beta-globin locus control region confers an early embryonic erythroid-specific expression pattern to a basic promoter driving the bacterial lacZ gene.
    Tewari R, Gillemans N, Harper A, Wijgerde M, Zafarana G, Drabek D, Grosveld F, Philipsen S.
    Development; 1996 Dec; 122(12):3991-9. PubMed ID: 9012519
    [Abstract] [Full Text] [Related]

  • 2. Full activity from human beta-globin locus control region transgenes requires 5'HS1, distal beta-globin promoter, and 3' beta-globin sequences.
    Pasceri P, Pannell D, Wu X, Ellis J.
    Blood; 1998 Jul 15; 92(2):653-63. PubMed ID: 9657768
    [Abstract] [Full Text] [Related]

  • 3. Deletion of the human beta-globin LCR 5'HS4 or 5'HS1 differentially affects beta-like globin gene expression in beta-YAC transgenic mice.
    Fedosyuk H, Peterson KR.
    Blood Cells Mol Dis; 2007 Jul 15; 39(1):44-55. PubMed ID: 17433733
    [Abstract] [Full Text] [Related]

  • 4. The mouse beta-globin locus control region: hypersensitive sites 3 and 4.
    Jiménez G, Gale KB, Enver T.
    Nucleic Acids Res; 1992 Nov 11; 20(21):5797-803. PubMed ID: 1454540
    [Abstract] [Full Text] [Related]

  • 5. Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice.
    Peterson KR, Clegg CH, Navas PA, Norton EJ, Kimbrough TG, Stamatoyannopoulos G.
    Proc Natl Acad Sci U S A; 1996 Jun 25; 93(13):6605-9. PubMed ID: 8692864
    [Abstract] [Full Text] [Related]

  • 6. The beta-globin promoter is important for recruitment of erythroid Krüppel-like factor to the locus control region in erythroid cells.
    Lee JS, Lee CH, Chung JH.
    Proc Natl Acad Sci U S A; 1999 Aug 31; 96(18):10051-5. PubMed ID: 10468560
    [Abstract] [Full Text] [Related]

  • 7. DNase I hypersensitivity and epsilon-globin transcriptional enhancement are separable in locus control region (LCR) HS1 mutant human beta-globin YAC transgenic mice.
    Shimotsuma M, Okamura E, Matsuzaki H, Fukamizu A, Tanimoto K.
    J Biol Chem; 2010 May 07; 285(19):14495-503. PubMed ID: 20231293
    [Abstract] [Full Text] [Related]

  • 8. The 5'HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis.
    Navas PA, Peterson KR, Li Q, McArthur M, Stamatoyannopoulos G.
    J Mol Biol; 2001 Sep 07; 312(1):17-26. PubMed ID: 11545582
    [Abstract] [Full Text] [Related]

  • 9. Erythroid Krüppel-like factor (EKLF) is active in primitive and definitive erythroid cells and is required for the function of 5'HS3 of the beta-globin locus control region.
    Tewari R, Gillemans N, Wijgerde M, Nuez B, von Lindern M, Grosveld F, Philipsen S.
    EMBO J; 1998 Apr 15; 17(8):2334-41. PubMed ID: 9545245
    [Abstract] [Full Text] [Related]

  • 10. Locus control region activity by 5'HS3 requires a functional interaction with beta-globin gene regulatory elements: expression of novel beta/gamma-globin hybrid transgenes.
    Rubin JE, Pasceri P, Wu X, Leboulch P, Ellis J.
    Blood; 2000 May 15; 95(10):3242-9. PubMed ID: 10807795
    [Abstract] [Full Text] [Related]

  • 11. LCR 5' hypersensitive site specificity for globin gene activation within the active chromatin hub.
    Peterson KR, Fedosyuk H, Harju-Baker S.
    Nucleic Acids Res; 2012 Dec 15; 40(22):11256-69. PubMed ID: 23042246
    [Abstract] [Full Text] [Related]

  • 12. Synergistic and additive properties of the beta-globin locus control region (LCR) revealed by 5'HS3 deletion mutations: implication for LCR chromatin architecture.
    Fang X, Sun J, Xiang P, Yu M, Navas PA, Peterson KR, Stamatoyannopoulos G, Li Q.
    Mol Cell Biol; 2005 Aug 15; 25(16):7033-41. PubMed ID: 16055715
    [Abstract] [Full Text] [Related]

  • 13. Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.
    Ellis J, Pasceri P, Tan-Un KC, Wu X, Harper A, Fraser P, Grosveld F.
    Nucleic Acids Res; 1997 Mar 15; 25(6):1296-302. PubMed ID: 9092642
    [Abstract] [Full Text] [Related]

  • 14. Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.
    Fiering S, Epner E, Robinson K, Zhuang Y, Telling A, Hu M, Martin DI, Enver T, Ley TJ, Groudine M.
    Genes Dev; 1995 Sep 15; 9(18):2203-13. PubMed ID: 7557375
    [Abstract] [Full Text] [Related]

  • 15. Targeted deletion of 5'HS1 and 5'HS4 of the beta-globin locus control region reveals additive activity of the DNaseI hypersensitive sites.
    Bender MA, Roach JN, Halow J, Close J, Alami R, Bouhassira EE, Groudine M, Fiering SN.
    Blood; 2001 Oct 01; 98(7):2022-7. PubMed ID: 11567985
    [Abstract] [Full Text] [Related]

  • 16. Substitution of the human beta-spectrin promoter for the human agamma-globin promoter prevents silencing of a linked human beta-globin gene in transgenic mice.
    Sabatino DE, Cline AP, Gallagher PG, Garrett LJ, Stamatoyannopoulos G, Forget BG, Bodine DM.
    Mol Cell Biol; 1998 Nov 01; 18(11):6634-40. PubMed ID: 9774678
    [Abstract] [Full Text] [Related]

  • 17. Gamma-globin gene promoter elements required for interaction with globin enhancers.
    Langdon SD, Kaufman RE.
    Blood; 1998 Jan 01; 91(1):309-18. PubMed ID: 9414299
    [Abstract] [Full Text] [Related]

  • 18. A dominant chromatin-opening activity in 5' hypersensitive site 3 of the human beta-globin locus control region.
    Ellis J, Tan-Un KC, Harper A, Michalovich D, Yannoutsos N, Philipsen S, Grosveld F.
    EMBO J; 1996 Feb 01; 15(3):562-8. PubMed ID: 8599939
    [Abstract] [Full Text] [Related]

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  • 20. LCR-regulated transgene expression levels depend on the Oct-1 site in the AT-rich region of beta -globin intron-2.
    Bharadwaj RR, Trainor CD, Pasceri P, Ellis J.
    Blood; 2003 Feb 15; 101(4):1603-10. PubMed ID: 12393478
    [Abstract] [Full Text] [Related]

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