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143 related items for PubMed ID: 9043660
1. Synthesis and biological activity of semipeptoid farnesyltransferase inhibitors. Reuveni H, Gitler A, Poradosu E, Gilon C, Levitzki A. Bioorg Med Chem; 1997 Jan; 5(1):85-92. PubMed ID: 9043660 [Abstract] [Full Text] [Related]
2. Synthesis and conformational analysis of peptide inhibitors of farnesyltransferase. Byk G, Lelievre Y, Duchesne M, Clerc FF, Scherman D, Guitton JD. Bioorg Med Chem; 1997 Jan; 5(1):115-24. PubMed ID: 9043663 [Abstract] [Full Text] [Related]
3. Pseudopeptide inhibitors of Ras farnesyl-protein transferase. Graham SL, deSolms SJ, Giuliani EA, Kohl NE, Mosser SD, Oliff AI, Pompliano DL, Rands E, Breslin MJ, Deana AA. J Med Chem; 1994 Mar 18; 37(6):725-32. PubMed ID: 8145221 [Abstract] [Full Text] [Related]
4. Synthesis of characteristic lipopeptides of the human N-Ras protein and their evaluation as possible inhibitors of protein farnesyl transferase. Stöber P, Schelhaas M, Nägele E, Hagenbuch P, Rétey J, Waldmann H. Bioorg Med Chem; 1997 Jan 18; 5(1):75-83. PubMed ID: 9043659 [Abstract] [Full Text] [Related]
5. Development of highly potent inhibitors of Ras farnesyltransferase possessing cellular and in vivo activity. Leftheris K, Kline T, Vite GD, Cho YH, Bhide RS, Patel DV, Patel MM, Schmidt RJ, Weller HN, Andahazy ML, Carboni JM, Gullo-Brown JL, Lee FY, Ricca C, Rose WC, Yan N, Barbacid M, Hunt JT, Meyers CA, Seizinger BR, Zahler R, Manne V. J Med Chem; 1996 Jan 05; 39(1):224-36. PubMed ID: 8568812 [Abstract] [Full Text] [Related]
6. Bisubstrate inhibitors of farnesyltransferase: a novel class of specific inhibitors of ras transformed cells. Manne V, Yan N, Carboni JM, Tuomari AV, Ricca CS, Brown JG, Andahazy ML, Schmidt RJ, Patel D, Zahler R. Oncogene; 1995 May 04; 10(9):1763-79. PubMed ID: 7753553 [Abstract] [Full Text] [Related]
7. Pseudodipeptide inhibitors of protein farnesyltransferase. deSolms SJ, Deana AA, Giuliani EA, Graham SL, Kohl NE, Mosser SD, Oliff AI, Pompliano DL, Rands E, Scholz TH. J Med Chem; 1995 Sep 29; 38(20):3967-71. PubMed ID: 7562930 [Abstract] [Full Text] [Related]
8. Disruption of oncogenic K-Ras4B processing and signaling by a potent geranylgeranyltransferase I inhibitor. Lerner EC, Qian Y, Hamilton AD, Sebti SM. J Biol Chem; 1995 Nov 10; 270(45):26770-3. PubMed ID: 7592913 [Abstract] [Full Text] [Related]
9. J-104,871, a novel farnesyltransferase inhibitor, blocks Ras farnesylation in vivo in a farnesyl pyrophosphate-competitive manner. Yonemoto M, Satoh T, Arakawa H, Suzuki-Takahashi I, Monden Y, Kodera T, Tanaka K, Aoyama T, Iwasawa Y, Kamei T, Nishimura S, Tomimoto K. Mol Pharmacol; 1998 Jul 10; 54(1):1-7. PubMed ID: 9658183 [Abstract] [Full Text] [Related]
17. Farnesyl protein transferase inhibitors as potential cancer chemopreventives. Kelloff GJ, Lubet RA, Fay JR, Steele VE, Boone CW, Crowell JA, Sigman CC. Cancer Epidemiol Biomarkers Prev; 1997 Apr 10; 6(4):267-82. PubMed ID: 9107432 [Abstract] [Full Text] [Related]
18. Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models. Lobell RB, Omer CA, Abrams MT, Bhimnathwala HG, Brucker MJ, Buser CA, Davide JP, deSolms SJ, Dinsmore CJ, Ellis-Hutchings MS, Kral AM, Liu D, Lumma WC, Machotka SV, Rands E, Williams TM, Graham SL, Hartman GD, Oliff AI, Heimbrook DC, Kohl NE. Cancer Res; 2001 Dec 15; 61(24):8758-68. PubMed ID: 11751396 [Abstract] [Full Text] [Related]
19. Synthesis and biological activity of ras farnesyl protein transferase inhibitors. Tetrapeptide analogs with amino methyl and carbon linkages. Wai JS, Bamberger DL, Fisher TE, Graham SL, Smith RL, Gibbs JB, Mosser SD, Oliff AI, Pompliano DL, Rands E. Bioorg Med Chem; 1994 Sep 15; 2(9):939-47. PubMed ID: 7712129 [Abstract] [Full Text] [Related]
20. Alpha-cyanocinnamide derivatives: a new family of non-peptide, non-sulfhydryl inhibitors of Ras farnesylation. Poradosu E, Gazit A, Reuveni H, Levitzki A. Bioorg Med Chem; 1999 Aug 15; 7(8):1727-36. PubMed ID: 10482464 [Abstract] [Full Text] [Related] Page: [Next] [New Search]