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105 related items for PubMed ID: 9054363

  • 1. The biologic action of single-chain choriogonadotropin is not dependent on the individual disulfide bonds of the beta subunit.
    Ben-Menahem D, Kudo M, Pixley MR, Sato A, Suganuma N, Perlas E, Hsueh AJ, Boime I.
    J Biol Chem; 1997 Mar 14; 272(11):6827-30. PubMed ID: 9054363
    [Abstract] [Full Text] [Related]

  • 2. Disulfide bond mutations in follicle-stimulating hormone result in uncoupling of biological activity from intracellular behavior.
    Hiro'oka T, Maassen D, Berger P, Boime I.
    Endocrinology; 2000 Dec 14; 141(12):4751-6. PubMed ID: 11108290
    [Abstract] [Full Text] [Related]

  • 3. Cystine knot of the gonadotropin alpha subunit is critical for intracellular behavior but not for in vitro biological activity.
    Sato A, Perlas E, Ben-Menahem D, Kudo M, Pixley MR, Furuhashi M, Hsueh AJ, Boime I.
    J Biol Chem; 1997 Jul 18; 272(29):18098-103. PubMed ID: 9218442
    [Abstract] [Full Text] [Related]

  • 4. Mutagenesis of cysteine residues in the human gonadotropin alpha subunit. Roles of individual disulfide bonds in secretion, assembly, and biologic activity.
    Furuhashi M, Ando H, Bielinska M, Pixley MR, Shikone T, Hsueh AJ, Boime I.
    J Biol Chem; 1994 Oct 14; 269(41):25543-8. PubMed ID: 7929256
    [Abstract] [Full Text] [Related]

  • 5. The position of the alpha and beta subunits in a single chain variant of human chorionic gonadotropin affects the heterodimeric interaction of the subunits and receptor-binding epitopes.
    Ben-Menahem D, Jablonka-Shariff A, Hyde RK, Pixley MR, Srivastava S, Berger P, Boime I.
    J Biol Chem; 2001 Aug 10; 276(32):29871-9. PubMed ID: 11390409
    [Abstract] [Full Text] [Related]

  • 6. Disulfide bond rearrangement during formation of the chorionic gonadotropin beta-subunit cystine knot in vivo.
    Wilken JA, Bedows E.
    Biochemistry; 2004 May 04; 43(17):5109-18. PubMed ID: 15109270
    [Abstract] [Full Text] [Related]

  • 7. A novel four-amino acid determinant defines conformational freedom within chorionic gonadotropin beta-subunits.
    Wilken JA, Bedows E.
    Biochemistry; 2007 Apr 10; 46(14):4417-24. PubMed ID: 17358049
    [Abstract] [Full Text] [Related]

  • 8. Single-chain, triple-domain gonadotropin analogs with disulfide bond mutations in the alpha-subunit elicit dual follitropin and lutropin activities in vivo.
    Jablonka-Shariff A, Kumar TR, Eklund J, Comstock A, Boime I.
    Mol Endocrinol; 2006 Jun 10; 20(6):1437-46. PubMed ID: 16601070
    [Abstract] [Full Text] [Related]

  • 9. Partially deglycosylated human choriogonadotropin, stabilized by intersubunit disulfide bonds, shows full bioactivity.
    Heikoop JC, van den Boogaart P, de Leeuw R, Rose UM, Mulders JW, Grootenhuis PD.
    Eur J Biochem; 1998 Apr 01; 253(1):354-6. PubMed ID: 9578495
    [Abstract] [Full Text] [Related]

  • 10. Elimination of disulfide bonds affects assembly and secretion of the human chorionic gonadotropin beta subunit.
    Suganuma N, Matzuk MM, Boime I.
    J Biol Chem; 1989 Nov 15; 264(32):19302-7. PubMed ID: 2478557
    [Abstract] [Full Text] [Related]

  • 11. The biological action of choriogonadotropin is not dependent on the complete native quaternary interactions between the subunits.
    Jackson AM, Berger P, Pixley M, Klein C, Hsueh AJ, Boime I.
    Mol Endocrinol; 1999 Dec 15; 13(12):2175-88. PubMed ID: 10598590
    [Abstract] [Full Text] [Related]

  • 12. Disulfide bonds 7-31 and 59-87 of the alpha-subunit play a different role in assembly of human chorionic gonadotropin and lutropin.
    Furuhashi M, Suzuki S, Suganuma N.
    Endocrinology; 1996 Oct 15; 137(10):4196-200. PubMed ID: 8828477
    [Abstract] [Full Text] [Related]

  • 13. Effect of modification of all loop regions in the alpha- and beta-subunits of human choriogonadotropin on its signal transduction activity.
    Shao K, Purohit S, Bahl OP.
    Mol Cell Endocrinol; 1996 Sep 18; 122(2):173-82. PubMed ID: 8902847
    [Abstract] [Full Text] [Related]

  • 14. Structure-based design and protein engineering of intersubunit disulfide bonds in gonadotropins.
    Heikoop JC, van den Boogaart P, Mulders JW, Grootenhuis PD.
    Nat Biotechnol; 1997 Jul 18; 15(7):658-62. PubMed ID: 9219269
    [Abstract] [Full Text] [Related]

  • 15. Dissociation of early folding events from assembly of the human lutropin beta-subunit.
    Muyan M, Ruddon RW, Norton SE, Boime I, Bedows E.
    Mol Endocrinol; 1998 Oct 18; 12(10):1640-9. PubMed ID: 9773985
    [Abstract] [Full Text] [Related]

  • 16. Alternatively folded choriogonadotropin analogs. Implications for hormone folding and biological activity.
    Xing Y, Lin W, Jiang M, Myers RV, Cao D, Bernard MP, Moyle WR.
    J Biol Chem; 2001 Dec 14; 276(50):46953-60. PubMed ID: 11591722
    [Abstract] [Full Text] [Related]

  • 17. Protein folding and assembly in vitro parallel intracellular folding and assembly. Catalysis of folding and assembly of the human chorionic gonadotropin alpha beta dimer by protein disulfide isomerase.
    Huth JR, Perini F, Lockridge O, Bedows E, Ruddon RW.
    J Biol Chem; 1993 Aug 05; 268(22):16472-82. PubMed ID: 8344931
    [Abstract] [Full Text] [Related]

  • 18. Glycoprotein hormone assembly in the endoplasmic reticulum: IV. Probable mechanism of subunit docking and completion of assembly.
    Xing Y, Myers RV, Cao D, Lin W, Jiang M, Bernard MP, Moyle WR.
    J Biol Chem; 2004 Aug 20; 279(34):35458-68. PubMed ID: 15166248
    [Abstract] [Full Text] [Related]

  • 19. Mapping the receptor binding regions of human chorionic gonadotropin (hCG) using disulfide peptides of its beta-subunit: possible involvement of the disulfide bonds Cys(9)-Cys(57) and Cys(23)-Cys(72) in receptor binding of the hormone.
    Mishra AK, Mahale SD, Iyer KS.
    J Pept Res; 2001 Jul 20; 58(1):17-26. PubMed ID: 11454166
    [Abstract] [Full Text] [Related]

  • 20. Intracellular folding pathway of human chorionic gonadotropin beta subunit.
    Huth JR, Mountjoy K, Perini F, Ruddon RW.
    J Biol Chem; 1992 May 05; 267(13):8870-9. PubMed ID: 1577725
    [Abstract] [Full Text] [Related]


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