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Journal Abstract Search

175 related items for PubMed ID: 9073592

  • 1. The use of human in vitro metabolic parameters to explore the risk assessment of hazardous compounds: the case of ethylene dibromide.
    Ploemen JP, Wormhoudt LW, Haenen GR, Oudshoorn MJ, Commandeur JN, Vermeulen NP, de Waziers I, Beaune PH, Watabe T, van Bladeren PJ.
    Toxicol Appl Pharmacol; 1997 Mar; 143(1):56-69. PubMed ID: 9073592
    [Abstract] [Full Text] [Related]

  • 2. Selectivity of rat and human glutathione S-transferases in activation of ethylene dibromide by glutathione conjugation and DNA binding and induction of unscheduled DNA synthesis in human hepatocytes.
    Cmarik JL, Inskeep PB, Meredith MJ, Meyer DJ, Ketterer B, Guengerich FP.
    Cancer Res; 1990 May 01; 50(9):2747-52. PubMed ID: 2328501
    [Abstract] [Full Text] [Related]

  • 3. Rat hepatic glutathione S-transferase-mediated embryotoxic bioactivation of ethylene dibromide.
    Mitra A, Hilbelink DR, Dwornik JJ, Kulkarni A.
    Teratology; 1992 Nov 01; 46(5):439-46. PubMed ID: 1462248
    [Abstract] [Full Text] [Related]

  • 4. Screening and characterization of variant Theta-class glutathione transferases catalyzing the activation of ethylene dibromide to a mutagen.
    Josephy PD, Taylor PL, Vervaet G, Mannervik B.
    Environ Mol Mutagen; 2006 Dec 01; 47(9):657-65. PubMed ID: 16948056
    [Abstract] [Full Text] [Related]

  • 5. Urinary thiodiacetic acid. A selective biomarker for the cytochrome P450-catalyzed oxidation of 1,2-dibromoethane in the rat.
    Wormhoudt LW, Commandeur JN, Ploemen JH, Abdoelgafoer RS, Makansi A, Van Bladeren PJ, Vermeulen NP.
    Drug Metab Dispos; 1997 Apr 01; 25(4):508-15. PubMed ID: 9107551
    [Abstract] [Full Text] [Related]

  • 6. Low glutathione S-transferase dogs.
    Watanabe T, Sugiura T, Manabe S, Takasaki W, Ohashi Y.
    Arch Toxicol; 2004 Apr 01; 78(4):218-25. PubMed ID: 14685647
    [Abstract] [Full Text] [Related]

  • 7. Pharmacokinetics and metabolism of vinyl fluoride in vivo and in vitro.
    Cantoreggi S, Keller DA.
    Toxicol Appl Pharmacol; 1997 Mar 01; 143(1):130-9. PubMed ID: 9073601
    [Abstract] [Full Text] [Related]

  • 8. A physiologically based pharmacokinetic (PB-PK) model for 1,2-dichlorobenzene linked to two possible parameters of toxicity.
    Hissink AM, Van Ommen B, Krüse J, Van Bladeren PJ.
    Toxicol Appl Pharmacol; 1997 Aug 01; 145(2):301-10. PubMed ID: 9266803
    [Abstract] [Full Text] [Related]

  • 9. A physiologically based pharmacokinetic model for ethylene oxide in mouse, rat, and human.
    Fennell TR, Brown CD.
    Toxicol Appl Pharmacol; 2001 Jun 15; 173(3):161-75. PubMed ID: 11437638
    [Abstract] [Full Text] [Related]

  • 10. A physiologically-based pharmacokinetic(PB-PK) model for ethylene dibromide: relevance of extrahepatic metabolism.
    Hissink AM, Wormhoudt LW, Sherratt PJ, Hayes JD, Commandeur JN, Vermeulen NP, van Bladeren PJ.
    Food Chem Toxicol; 2000 Aug 15; 38(8):707-16. PubMed ID: 10908818
    [Abstract] [Full Text] [Related]

  • 11. Kinetics of propylene oxide metabolism in microsomes and cytosol of different organs from mouse, rat, and humans.
    Faller TH, Csanády GA, Kreuzer PE, Baur CM, Filser JG.
    Toxicol Appl Pharmacol; 2001 Apr 01; 172(1):62-74. PubMed ID: 11264024
    [Abstract] [Full Text] [Related]

  • 12. Glutathione S-transferase conjugation of organophosphorus pesticides yields S-phospho-, S-aryl-, and S-alkylglutathione derivatives.
    Fujioka K, Casida JE.
    Chem Res Toxicol; 2007 Aug 01; 20(8):1211-7. PubMed ID: 17645302
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of rat GSH S-transferases by ethylene dibromide.
    Ivanetich KM, Ziman MR, Mennie RE, Eidne KA, Corrigall A, Kirsch RE.
    Res Commun Chem Pathol Pharmacol; 1984 Aug 01; 45(2):233-42. PubMed ID: 6385169
    [Abstract] [Full Text] [Related]

  • 14. Comparative metabolism of 1,2,3,3,3-pentafluoropropene in male and female mouse, rat, dog, and human liver microsomes and cytosol and male rat hepatocytes via oxidative dehalogenation and glutathione S-conjugation pathways.
    Han X, Szostek B, Yang CH, Cheatham SF, Mingoia RT, Nabb DL, Gannon SA, Himmelstein MW, Jepson GW.
    Drug Metab Dispos; 2011 Jul 01; 39(7):1288-93. PubMed ID: 21493824
    [Abstract] [Full Text] [Related]

  • 15. Identification of the human liver microsomal cytochrome P450s involved in the metabolism of N-nitrosodi-n-propylamine.
    Teiber JF, Hollenberg PF.
    Carcinogenesis; 2000 Aug 01; 21(8):1559-66. PubMed ID: 10910959
    [Abstract] [Full Text] [Related]

  • 16. Cytochrome P450 2E1 is the principal catalyst of human oxidative halothane metabolism in vitro.
    Spracklin DK, Hankins DC, Fisher JM, Thummel KE, Kharasch ED.
    J Pharmacol Exp Ther; 1997 Apr 01; 281(1):400-11. PubMed ID: 9103523
    [Abstract] [Full Text] [Related]

  • 17. In vitro biotransformation and genotoxicity of the drinking water disinfection byproduct bromodichloromethane: DNA binding mediated by glutathione transferase theta 1-1.
    Ross MK, Pegram RA.
    Toxicol Appl Pharmacol; 2004 Mar 01; 195(2):166-81. PubMed ID: 14998683
    [Abstract] [Full Text] [Related]

  • 18. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug 01; (59):1-66, A1-E7. PubMed ID: 11803702
    [Abstract] [Full Text] [Related]

  • 19. Covalent binding of 1,2-dihaloalkanes to DNA and stability of the major DNA adduct, S-[2-(N7-guanyl)ethyl]glutathione.
    Inskeep PB, Koga N, Cmarik JL, Guengerich FP.
    Cancer Res; 1986 Jun 01; 46(6):2839-44. PubMed ID: 2870801
    [Abstract] [Full Text] [Related]

  • 20. Fentanyl metabolism by human hepatic and intestinal cytochrome P450 3A4: implications for interindividual variability in disposition, efficacy, and drug interactions.
    Labroo RB, Paine MF, Thummel KE, Kharasch ED.
    Drug Metab Dispos; 1997 Sep 01; 25(9):1072-80. PubMed ID: 9311623
    [Abstract] [Full Text] [Related]

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