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186 related items for PubMed ID: 9083085

  • 1. Heparin binding and oligomerization of hepatocyte growth factor/scatter factor isoforms. Heparan sulfate glycosaminoglycan requirement for Met binding and signaling.
    Sakata H, Stahl SJ, Taylor WG, Rosenberg JM, Sakaguchi K, Wingfield PT, Rubin JS.
    J Biol Chem; 1997 Apr 04; 272(14):9457-63. PubMed ID: 9083085
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  • 2. Hairpin loop and second kringle domain are essential sites for heparin binding and biological activity of hepatocyte growth factor.
    Mizuno K, Inoue H, Hagiya M, Shimizu S, Nose T, Shimohigashi Y, Nakamura T.
    J Biol Chem; 1994 Jan 14; 269(2):1131-6. PubMed ID: 8288571
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  • 3. Dissociation of heparan sulfate and receptor binding domains of hepatocyte growth factor reveals that heparan sulfate-c-met interaction facilitates signaling.
    Rubin JS, Day RM, Breckenridge D, Atabey N, Taylor WG, Stahl SJ, Wingfield PT, Kaufman JD, Schwall R, Bottaro DP.
    J Biol Chem; 2001 Aug 31; 276(35):32977-83. PubMed ID: 11435444
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  • 9. Heparan sulfate-modified CD44 promotes hepatocyte growth factor/scatter factor-induced signal transduction through the receptor tyrosine kinase c-Met.
    van der Voort R, Taher TE, Wielenga VJ, Spaargaren M, Prevo R, Smit L, David G, Hartmann G, Gherardi E, Pals ST.
    J Biol Chem; 1999 Mar 05; 274(10):6499-506. PubMed ID: 10037743
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  • 10. Signalling by HGF/SF and Met: the role of heparan sulphate co-receptors.
    Kemp LE, Mulloy B, Gherardi E.
    Biochem Soc Trans; 2006 Jun 05; 34(Pt 3):414-7. PubMed ID: 16709175
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  • 11. Mutational analysis and molecular modeling of the N-terminal kringle-containing domain of hepatocyte growth factor identifies amino acid side chains important for interaction with the c-Met receptor.
    Lokker NA, Presta LG, Godowski PJ.
    Protein Eng; 1994 Jul 05; 7(7):895-903. PubMed ID: 7971951
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  • 12. Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor.
    Lietha D, Chirgadze DY, Mulloy B, Blundell TL, Gherardi E.
    EMBO J; 2001 Oct 15; 20(20):5543-55. PubMed ID: 11597998
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  • 13. Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo.
    Hartmann G, Prospero T, Brinkmann V, Ozcelik C, Winter G, Hepple J, Batley S, Bladt F, Sachs M, Birchmeier C, Birchmeier W, Gherardi E.
    Curr Biol; 1998 Jan 29; 8(3):125-34. PubMed ID: 9443912
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  • 14. Crystal structure of the NK1 fragment of human hepatocyte growth factor at 2.0 A resolution.
    Ultsch M, Lokker NA, Godowski PJ, de Vos AM.
    Structure; 1998 Nov 15; 6(11):1383-93. PubMed ID: 9817840
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  • 15. A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis.
    Hartmann G, Naldini L, Weidner KM, Sachs M, Vigna E, Comoglio PM, Birchmeier W.
    Proc Natl Acad Sci U S A; 1992 Dec 01; 89(23):11574-8. PubMed ID: 1280830
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  • 16. The mode of action of heparan and dermatan sulfates in the regulation of hepatocyte growth factor/scatter factor.
    Lyon M, Deakin JA, Gallagher JT.
    J Biol Chem; 2002 Jan 11; 277(2):1040-6. PubMed ID: 11689562
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  • 17. Differential mitogenic effects of single chain hepatocyte growth factor (HGF)/scatter factor and HGF/NK1 following cleavage by factor Xa.
    Pediaditakis P, Monga SP, Mars WM, Michalopoulos GK.
    J Biol Chem; 2002 Apr 19; 277(16):14109-15. PubMed ID: 11832492
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  • 18. Insights into the structure of hepatocyte growth factor/scatter factor (HGF/SF) and implications for receptor activation.
    Chirgadze DY, Hepple J, Byrd RA, Sowdhamini R, Blundell TL, Gherardi E.
    FEBS Lett; 1998 Jun 23; 430(1-2):126-9. PubMed ID: 9678607
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  • 19. Hepatocyte growth factor/scatter factor binds to small heparin-derived oligosaccharides and stimulates the proliferation of human HaCaT keratinocytes.
    Delehedde M, Lyon M, Vidyasagar R, McDonnell TJ, Fernig DG.
    J Biol Chem; 2002 Apr 05; 277(14):12456-62. PubMed ID: 11799124
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  • 20. Structural and functional basis of the serine protease-like hepatocyte growth factor beta-chain in Met binding and signaling.
    Kirchhofer D, Yao X, Peek M, Eigenbrot C, Lipari MT, Billeci KL, Maun HR, Moran P, Santell L, Wiesmann C, Lazarus RA.
    J Biol Chem; 2004 Sep 17; 279(38):39915-24. PubMed ID: 15218027
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