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Journal Abstract Search


413 related items for PubMed ID: 9083478

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  • 2. Cyclic HIV-1 protease inhibitors derived from mannitol: synthesis, inhibitory potencies, and computational predictions of binding affinities.
    Hultén J, Bonham NM, Nillroth U, Hansson T, Zuccarello G, Bouzide A, Aqvist J, Classon B, Danielson UH, Karlén A, Kvarnström I, Samuelsson B, Hallberg A.
    J Med Chem; 1997 Mar 14; 40(6):885-97. PubMed ID: 9083477
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  • 4. Cyclic sulfamide HIV-1 protease inhibitors, with sidechains spanning from P2/P2' to P1/P1'.
    Ax A, Schaal W, Vrang L, Samuelsson B, Hallberg A, Karlén A.
    Bioorg Med Chem; 2005 Feb 01; 13(3):755-64. PubMed ID: 15653343
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  • 8. Comparing the conformational behavior of a series of diastereomeric cyclic urea HIV-1 inhibitors using the low mode:monte carlo conformational search method.
    Parish CA, Yarger M, Sinclair K, Dure M, Goldberg A.
    J Med Chem; 2004 Sep 23; 47(20):4838-50. PubMed ID: 15369387
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  • 10. Inhibitor binding at the protein interface in crystals of a HIV-1 protease complex.
    Brynda J, Rezácová P, Fábry M, Horejsí M, Stouracová R, Soucek M, Hradílek M, Konvalinka J, Sedlácek J.
    Acta Crystallogr D Biol Crystallogr; 2004 Nov 23; 60(Pt 11):1943-8. PubMed ID: 15502300
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  • 11. Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation.
    Clemente JC, Robbins A, Graña P, Paleo MR, Correa JF, Villaverde MC, Sardina FJ, Govindasamy L, Agbandje-McKenna M, McKenna R, Dunn BM, Sussman F.
    J Med Chem; 2008 Feb 28; 51(4):852-60. PubMed ID: 18215016
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  • 13. Two solutions for the same problem: multiple binding modes of pyrrolidine-based HIV-1 protease inhibitors.
    Blum A, Böttcher J, Dörr S, Heine A, Klebe G, Diederich WE.
    J Mol Biol; 2011 Jul 22; 410(4):745-55. PubMed ID: 21762812
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  • 16. Synthesis and comparative molecular field analysis (CoMFA) of symmetric and nonsymmetric cyclic sulfamide HIV-1 protease inhibitors.
    Schaal W, Karlsson A, Ahlsén G, Lindberg J, Andersson HO, Danielson UH, Classon B, Unge T, Samuelsson B, Hultén J, Hallberg A, Karlén A.
    J Med Chem; 2001 Jan 18; 44(2):155-69. PubMed ID: 11170625
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  • 17. Microwave-accelerated synthesis of P1'-extended HIV-1 protease inhibitors encompassing a tertiary alcohol in the transition-state mimicking scaffold.
    Ekegren JK, Ginman N, Johansson A, Wallberg H, Larhed M, Samuelsson B, Unge T, Hallberg A.
    J Med Chem; 2006 Mar 09; 49(5):1828-32. PubMed ID: 16509598
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  • 18. Synthesis and antiviral activity of P1' arylsulfonamide azacyclic urea HIV protease inhibitors.
    Huang PP, Randolph JT, Klein LL, Vasavanonda S, Dekhtyar T, Stoll VS, Kempf DJ.
    Bioorg Med Chem Lett; 2004 Aug 02; 14(15):4075-8. PubMed ID: 15225729
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  • 19. Synthesis and biological evaluation of novel amprenavir-based P1-substituted bi-aryl derivatives as ultra-potent HIV-1 protease inhibitors.
    Yan J, Huang N, Li S, Yang LM, Xing W, Zheng YT, Hu Y.
    Bioorg Med Chem Lett; 2012 Mar 01; 22(5):1976-9. PubMed ID: 22306123
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