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Journal Abstract Search

121 related items for PubMed ID: 9089816

  • 1. A strong thrombin-inhibitory prourokinase derivative with sequence elements from hirudin and the human thrombin receptor.
    Wnendt S, Janocha E, Steffens GJ, Strassburger W.
    Protein Eng; 1997 Feb; 10(2):169-73. PubMed ID: 9089816
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  • 2. Construction and structure-activity relationships of chimeric prourokinase derivatives with intrinsic thrombin-inhibitory potential.
    Wnendt S, Janocha E, Schneider J, Steffens GJ.
    Protein Eng; 1996 Feb; 9(2):213-23. PubMed ID: 9005443
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  • 4. Modular design of a novel chimeric protein with combined thrombin inhibitory activity and plasminogen-activating potential.
    Wirsching F, Luge C, Schwienhorst A.
    Mol Genet Metab; 2002 Mar; 75(3):250-9. PubMed ID: 11914037
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  • 5. A novel chimaeric derivative of saruplase, rscu-PA-40 kDA/Hir, binds to thrombin and exerts thrombus-specific fibrinolysis in arterial and venous thrombosis in dogs.
    Schneider J, Hauser R, Hennies HH, Korioth J, Steffens G, Wnendt S.
    Thromb Haemost; 1997 Mar; 77(3):535-9. PubMed ID: 9066007
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  • 6. The region of the thrombin receptor resembling hirudin binds to thrombin and alters enzyme specificity.
    Liu LW, Vu TK, Esmon CT, Coughlin SR.
    J Biol Chem; 1991 Sep 15; 266(26):16977-80. PubMed ID: 1654318
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  • 7. Structure-activity relationships of recombinant hirudins.
    Stürzebecher J, Walsmann P.
    Semin Thromb Hemost; 1991 Apr 15; 17(2):94-8. PubMed ID: 1771418
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  • 8. Structure-function and refolding studies of the thrombin-specific inhibitor hirudin.
    Johnson PH, Sze P, Winant RC, Hudson D, Underhill P, Lazar JB, Olsen C, Almquist R.
    Haemostasis; 1991 Apr 15; 21 Suppl 1():41-8. PubMed ID: 1894196
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  • 9. Production, properties, and thrombin inhibitory mechanism of hirudin amino-terminal core fragments.
    Chang JY.
    J Biol Chem; 1990 Dec 25; 265(36):22159-66. PubMed ID: 2266119
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  • 10. Rational design of hirulog-type inhibitors of thrombin.
    Egner U, Hoyer GA, Schleuning WD.
    J Comput Aided Mol Des; 1994 Oct 25; 8(5):479-90. PubMed ID: 7876896
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  • 11. Design of potent bivalent thrombin inhibitors based on hirudin sequence: incorporation of nonsubstrate-type active site inhibitors.
    Tsuda Y, Cygler M, Gibbs BF, Pedyczak A, Féthière J, Yue SY, Konishi Y.
    Biochemistry; 1994 Dec 06; 33(48):14443-51. PubMed ID: 7981204
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  • 16. Thermodynamic investigation of hirudin binding to the slow and fast forms of thrombin: evidence for folding transitions in the inhibitor and protease coupled to binding.
    Ayala YM, Vindigni A, Nayal M, Spolar RS, Record MT, Di Cera E.
    J Mol Biol; 1995 Nov 10; 253(5):787-98. PubMed ID: 7473752
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  • 17. Structure-function relationships of the C-terminal functional domain of hirudin and its variants.
    Krstenansky JL, Mao SJ.
    Blood Coagul Fibrinolysis; 1991 Feb 10; 2(1):91-6. PubMed ID: 1773003
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  • 18. Domain-domain interactions in hybrids of tissue-type plasminogen activator and urokinase-type plasminogen activator.
    Bakker AH, Nieuwenbroek NM, Verheijen JH.
    Protein Eng; 1995 Dec 10; 8(12):1295-1302. PubMed ID: 8869642
    [Abstract] [Full Text] [Related]

  • 19. Interaction of the N-terminal region of hirudin with the active-site cleft of thrombin.
    Betz A, Hofsteenge J, Stone SR.
    Biochemistry; 1992 May 19; 31(19):4557-62. PubMed ID: 1581311
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  • 20. Probing the hirudin-thrombin interaction by incorporation of noncoded amino acids and molecular dynamics simulation.
    De Filippis V, Colombo G, Russo I, Spadari B, Fontana A.
    Biochemistry; 2002 Nov 19; 41(46):13556-69. PubMed ID: 12427016
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