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2327 related items for PubMed ID: 9108451

  • 1. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
    Akiyama T, Yoshida T, Tsujita T, Shimizu M, Mizukami T, Okabe M, Akinaga S.
    Cancer Res; 1997 Apr 15; 57(8):1495-501. PubMed ID: 9108451
    [Abstract] [Full Text] [Related]

  • 2. Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1).
    Patel V, Lahusen T, Leethanakul C, Igishi T, Kremer M, Quintanilla-Martinez L, Ensley JF, Sausville EA, Gutkind JS, Senderowicz AM.
    Clin Cancer Res; 2002 Nov 15; 8(11):3549-60. PubMed ID: 12429646
    [Abstract] [Full Text] [Related]

  • 3. G1-checkpoint function including a cyclin-dependent kinase 2 regulatory pathway as potential determinant of 7-hydroxystaurosporine (UCN-01)-induced apoptosis and G1-phase accumulation.
    Akiyama T, Sugiyama K, Shimizu M, Tamaoki T, Akinaga S.
    Jpn J Cancer Res; 1999 Dec 15; 90(12):1364-72. PubMed ID: 10665655
    [Abstract] [Full Text] [Related]

  • 4. Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.
    Rao S, Lowe M, Herliczek TW, Keyomarsi K.
    Oncogene; 1998 Nov 05; 17(18):2393-402. PubMed ID: 9811471
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate.
    Liang YC, Lin-Shiau SY, Chen CF, Lin JK.
    J Cell Biochem; 1999 Oct 01; 75(1):1-12. PubMed ID: 10462699
    [Abstract] [Full Text] [Related]

  • 6. Decrease in susceptibility toward induction of apoptosis and alteration in G1 checkpoint function as determinants of resistance of human lung cancer cells against the antisignaling drug UCN-01 (7-Hydroxystaurosporine).
    Sugiyama K, Akiyama T, Shimizu M, Tamaoki T, Courage C, Gescher A, Akinaga S.
    Cancer Res; 1999 Sep 01; 59(17):4406-12. PubMed ID: 10485490
    [Abstract] [Full Text] [Related]

  • 7. Disruption of the actin cytoskeleton leads to inhibition of mitogen-induced cyclin E expression, Cdk2 phosphorylation, and nuclear accumulation of the retinoblastoma protein-related p107 protein.
    Reshetnikova G, Barkan R, Popov B, Nikolsky N, Chang LS.
    Exp Cell Res; 2000 Aug 25; 259(1):35-53. PubMed ID: 10942577
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of the melanoma cell cycle and regulation at the G1/S transition by 12-O-tetradecanoylphorbol-13-acetate (TPA) by modulation of CDK2 activity.
    Coppock DL, Buffolino P, Kopman C, Nathanson L.
    Exp Cell Res; 1995 Nov 25; 221(1):92-102. PubMed ID: 7589260
    [Abstract] [Full Text] [Related]

  • 9. Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells.
    Di Gennaro E, Barbarino M, Bruzzese F, De Lorenzo S, Caraglia M, Abbruzzese A, Avallone A, Comella P, Caponigro F, Pepe S, Budillon A.
    J Cell Physiol; 2003 Apr 25; 195(1):139-50. PubMed ID: 12599217
    [Abstract] [Full Text] [Related]

  • 10. Blockade of tumor cell transforming growth factor-betas enhances cell cycle progression and sensitizes human breast carcinoma cells to cytotoxic chemotherapy.
    Ohmori T, Yang JL, Price JO, Arteaga CL.
    Exp Cell Res; 1998 Dec 15; 245(2):350-9. PubMed ID: 9851876
    [Abstract] [Full Text] [Related]

  • 11. Transforming growth factor beta 1 increases the stability of p21/WAF1/CIP1 protein and inhibits CDK2 kinase activity in human colon carcinoma FET cells.
    Gong J, Ammanamanchi S, Ko TC, Brattain MG.
    Cancer Res; 2003 Jun 15; 63(12):3340-6. PubMed ID: 12810668
    [Abstract] [Full Text] [Related]

  • 12. Induction of p53-independent p21 during ceramide-induced G1 arrest in human hepatocarcinoma cells.
    Kim WH, Kang KH, Kim MY, Choi KH.
    Biochem Cell Biol; 2000 Jun 15; 78(2):127-35. PubMed ID: 10874474
    [Abstract] [Full Text] [Related]

  • 13. TGF-beta-mediated cell cycle arrest of HPV16-immortalized human ectocervical cells correlates with decreased E6/E7 mRNA and increased p53 and p21(WAF-1) expression.
    Rorke EA, Zhang D, Choo CK, Eckert RL, Jacobberger JW.
    Exp Cell Res; 2000 Aug 25; 259(1):149-57. PubMed ID: 10942587
    [Abstract] [Full Text] [Related]

  • 14. Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins.
    Sangfelt O, Erickson S, Castro J, Heiden T, Gustafsson A, Einhorn S, Grandér D.
    Oncogene; 1999 May 06; 18(18):2798-810. PubMed ID: 10362250
    [Abstract] [Full Text] [Related]

  • 15. Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines.
    Koga H, Sakisaka S, Harada M, Takagi T, Hanada S, Taniguchi E, Kawaguchi T, Sasatomi K, Kimura R, Hashimoto O, Ueno T, Yano H, Kojiro M, Sata M.
    Hepatology; 2001 May 06; 33(5):1087-97. PubMed ID: 11343236
    [Abstract] [Full Text] [Related]

  • 16. Cytoplasmic displacement of cyclin E-cdk2 inhibitors p21Cip1 and p27Kip1 in anchorage-independent cells.
    Orend G, Hunter T, Ruoslahti E.
    Oncogene; 1998 May 06; 16(20):2575-83. PubMed ID: 9632134
    [Abstract] [Full Text] [Related]

  • 17. Formation of p27-CDK complexes during the human mitotic cell cycle.
    Soos TJ, Kiyokawa H, Yan JS, Rubin MS, Giordano A, DeBlasio A, Bottega S, Wong B, Mendelsohn J, Koff A.
    Cell Growth Differ; 1996 Feb 06; 7(2):135-46. PubMed ID: 8822197
    [Abstract] [Full Text] [Related]

  • 18. Hyperoxia induces S-phase cell-cycle arrest and p21(Cip1/Waf1)-independent Cdk2 inhibition in human carcinoma T47D-H3 cells.
    Bilodeau JF, Faure R, Piedboeuf B, Mirault ME.
    Exp Cell Res; 2000 May 01; 256(2):347-57. PubMed ID: 10772807
    [Abstract] [Full Text] [Related]

  • 19. Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex.
    Yin MB, Guo B, Panadero A, Frank C, Wrzosek C, Slocum HK, Rustum YM.
    Exp Cell Res; 1999 Feb 25; 247(1):189-99. PubMed ID: 10047461
    [Abstract] [Full Text] [Related]

  • 20. Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27(Kip1) in the cyclin E-cdk2 complexes.
    Nahum A, Hirsch K, Danilenko M, Watts CK, Prall OW, Levy J, Sharoni Y.
    Oncogene; 2001 Jun 07; 20(26):3428-36. PubMed ID: 11423993
    [Abstract] [Full Text] [Related]

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