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Journal Abstract Search

268 related items for PubMed ID: 9108546

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  • 6. Novel alleles of the Plasmodium falciparum dhfr highly resistant to pyrimethamine and chlorcycloguanil, but not WR99210.
    Hankins EG, Warhurst DC, Sibley CH.
    Mol Biochem Parasitol; 2001 Sep 28; 117(1):91-102. PubMed ID: 11551635
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  • 7. Antifolate resistance due to new and known Plasmodium falciparum dihydrofolate reductase mutations expressed in yeast.
    Cortese JF, Plowe CV.
    Mol Biochem Parasitol; 1998 Aug 01; 94(2):205-14. PubMed ID: 9747971
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  • 8. Pyrimethamine and WR99210 exert opposing selection on dihydrofolate reductase from Plasmodium vivax.
    Hastings MD, Sibley CH.
    Proc Natl Acad Sci U S A; 2002 Oct 01; 99(20):13137-41. PubMed ID: 12198181
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  • 9. An amino acid substitution in the Babesia bovis dihydrofolate reductase-thymidylate synthase gene is correlated to cross-resistance against pyrimethamine and WR99210.
    Gaffar FR, Wilschut K, Franssen FF, de Vries E.
    Mol Biochem Parasitol; 2004 Feb 01; 133(2):209-19. PubMed ID: 14698433
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  • 10. Pyrimethamine analogs as strong inhibitors of double and quadruple mutants of dihydrofolate reductase in human malaria parasites.
    Sardarian A, Douglas KT, Read M, Sims PF, Hyde JE, Chitnumsub P, Sirawaraporn R, Sirawaraporn W.
    Org Biomol Chem; 2003 Mar 21; 1(6):960-4. PubMed ID: 12929634
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  • 11. Identifying antimalarial compounds targeting dihydrofolate reductase-thymidylate synthase (DHFR-TS) by chemogenomic profiling.
    Aroonsri A, Akinola O, Posayapisit N, Songsungthong W, Uthaipibull C, Kamchonwongpaisan S, Gbotosho GO, Yuthavong Y, Shaw PJ.
    Int J Parasitol; 2016 Jul 21; 46(8):527-35. PubMed ID: 27150044
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  • 12. Transgenic Plasmodium parasites stably expressing Plasmodium vivax dihydrofolate reductase-thymidylate synthase as in vitro and in vivo models for antifolate screening.
    Somsak V, Uthaipibull C, Prommana P, Srichairatanakool S, Yuthavong Y, Kamchonwongpaisan S.
    Malar J; 2011 Oct 07; 10():291. PubMed ID: 21981896
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  • 13. Recombinant Plasmodium falciparum dihydrofolate reductase-based in vitro screen for antifolate antimalarials.
    Brobey RK, Sano G, Itoh F, Aso K, Kimura M, Mitamura T, Horii T.
    Mol Biochem Parasitol; 1996 Oct 30; 81(2):225-37. PubMed ID: 8898337
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  • 14. Identification and analysis of dihydrofolate reductase alleles from Plasmodium falciparum present at low frequency in polyclonal patient samples.
    Mookherjee S, Howard V, Nzila-Mouanda A, Watkins W, Sibley CH.
    Am J Trop Med Hyg; 1999 Jul 30; 61(1):131-40. PubMed ID: 10432070
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  • 15. Cycloguanil and its parent compound proguanil demonstrate distinct activities against Plasmodium falciparum malaria parasites transformed with human dihydrofolate reductase.
    Fidock DA, Nomura T, Wellems TE.
    Mol Pharmacol; 1998 Dec 30; 54(6):1140-7. PubMed ID: 9855645
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  • 16. Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil.
    Fidock DA, Wellems TE.
    Proc Natl Acad Sci U S A; 1997 Sep 30; 94(20):10931-6. PubMed ID: 9380737
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  • 17. Point mutations in the dihydrofolate reductase and dihydropteroate synthetase genes and in vitro susceptibility to pyrimethamine and cycloguanil of Plasmodium falciparum isolates from Papua New Guinea.
    Reeder JC, Rieckmann KH, Genton B, Lorry K, Wines B, Cowman AF.
    Am J Trop Med Hyg; 1996 Aug 30; 55(2):209-13. PubMed ID: 8780462
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  • 18. The dihydrofolate reductase-thymidylate synthetase gene in the drug resistance of malaria parasites.
    Hyde JE.
    Pharmacol Ther; 1990 Aug 30; 48(1):45-59. PubMed ID: 2274577
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  • 19. Plasmodium falciparum: mutation pattern in the dihydrofolate reductase-thymidylate synthase genes of Vietnamese isolates, a novel mutation, and coexistence of two clones in a Thai patient.
    Zindrou S, Nguyen PD, Nguyen DS, Sköld O, Swedberg G.
    Exp Parasitol; 1996 Oct 30; 84(1):56-64. PubMed ID: 8888732
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  • 20. Plasmodium falciparum: asparagine mutant at residue 108 of dihydrofolate reductase is an optimal antifolate-resistant single mutant.
    Sirawaraporn W, Yongkiettrakul S, Sirawaraporn R, Yuthavong Y, Santi DV.
    Exp Parasitol; 1997 Nov 30; 87(3):245-52. PubMed ID: 9371090
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