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Journal Abstract Search


127 related items for PubMed ID: 9109404

  • 1. Aspartate-474 in the first exoplasmic loop of the thyrotropin receptor is crucial for receptor activation.
    Kosugi S, Matsuda A, Hai N, Aoki N, Sugawa H, Mori T.
    FEBS Lett; 1997 Apr 07; 406(1-2):139-41. PubMed ID: 9109404
    [Abstract] [Full Text] [Related]

  • 2. Differential responses of an invariant region in the ectodomain of three glycoprotein hormone receptors to mutagenesis and assay conditions.
    Angelova K, Puett D.
    Endocrine; 2002 Nov 07; 19(2):147-54. PubMed ID: 12588044
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  • 3. High affinity binding of thyrotropin (TSH) and thyroid-stimulating autoantibody for the TSH receptor extracellular domain.
    Nagayama Y, Takeshita A, Luo W, Ashizawa K, Yokoyama N, Nagataki S.
    Thyroid; 1994 Nov 07; 4(2):155-9. PubMed ID: 7919997
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  • 4. Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3',5'-cyclic adenosine monophosphate signal generation.
    Kosugi S, Okajima F, Ban T, Hidaka A, Shenker A, Kohn LD.
    Mol Endocrinol; 1993 Aug 07; 7(8):1009-20. PubMed ID: 7901757
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  • 5. Identification of separate determinants on the thyrotropin receptor reactive with Graves' thyroid-stimulating antibodies and with thyroid-stimulating blocking antibodies in idiopathic myxedema: these determinants have no homologous sequence on gonadotropin receptors.
    Kosugi S, Ban T, Akamizu T, Kohn LD.
    Mol Endocrinol; 1992 Feb 07; 6(2):168-80. PubMed ID: 1349156
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  • 6. The third exoplasmic loop of the thyrotropin receptor is partially involved in signal transduction.
    Kosugi S, Mori T.
    FEBS Lett; 1994 Jul 25; 349(1):89-92. PubMed ID: 8045308
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  • 7. Chimeric studies of the extracellular domain of the rat thyrotropin (TSH) receptor: amino acids (268-304) in the TSH receptor are involved in ligand high affinity binding, but not in TSH receptor-specific signal transduction.
    Akamizu T, Inoue D, Kosugi S, Ban T, Kohn LD, Imura H, Mori T.
    Endocr J; 1993 Jun 25; 40(3):363-72. PubMed ID: 7920890
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  • 8. The middle portion in the second cytoplasmic loop of the thyrotropin receptor plays a crucial role in adenylate cyclase activation.
    Kosugi S, Kohn LD, Akamizu T, Mori T.
    Mol Endocrinol; 1994 Apr 25; 8(4):498-509. PubMed ID: 7914349
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  • 10. Cloning and functional expression of a thyrotropin receptor from the gonads of a vertebrate (bony fish): potential thyroid-independent role for thyrotropin in reproduction.
    Kumar RS, Ijiri S, Kight K, Swanson P, Dittman A, Alok D, Zohar Y, Trant JM.
    Mol Cell Endocrinol; 2000 Sep 25; 167(1-2):1-9. PubMed ID: 11000515
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  • 11. An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor.
    Urizar E, Claeysen S, Deupí X, Govaerts C, Costagliola S, Vassart G, Pardo L.
    J Biol Chem; 2005 Apr 29; 280(17):17135-41. PubMed ID: 15722344
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  • 13. Disruption of the first extracellular loop of thyrotropin receptor prevents ligand binding.
    Haraguchi K, Saito T, Endo T, Onaya T.
    Life Sci; 1994 Apr 29; 55(12):961-8. PubMed ID: 7914657
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  • 14. Thyrotropin stimulation of the lutropin/choriogonadotropin receptor: different sites mediate agonist activity and high affinity binding.
    Hidaka A, Ban T, Panesar NS, Minegishi T, Kohn LD, Tahara K.
    Thyroid; 1994 Apr 29; 4(4):447-57. PubMed ID: 7711510
    [Abstract] [Full Text] [Related]

  • 15. Proper targeting and activity of a nonfunctioning thyroid-stimulating hormone receptor (TSHr) combining an inactivating and activating TSHr mutation in one receptor.
    Agretti P, De Marco G, Collecchi P, Chiovato L, Vitti P, Pinchera A, Tonacchera M.
    Eur J Biochem; 2003 Sep 29; 270(18):3839-47. PubMed ID: 12950268
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  • 16. A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist.
    Claeysen S, Govaerts C, Lefort A, Van Sande J, Costagliola S, Pardo L, Vassart G.
    FEBS Lett; 2002 Apr 24; 517(1-3):195-200. PubMed ID: 12062436
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  • 17. Structural determinants for G-protein activation and specificity in the third intracellular loop of the thyroid-stimulating hormone receptor.
    Claus M, Neumann S, Kleinau G, Krause G, Paschke R.
    J Mol Med (Berl); 2006 Nov 24; 84(11):943-54. PubMed ID: 16955277
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  • 20. The superagonistic activity of bovine thyroid-stimulating hormone (TSH) and the human TR1401 TSH analog is determined by specific amino acids in the hinge region of the human TSH receptor.
    Mueller S, Kleinau G, Szkudlinski MW, Jaeschke H, Krause G, Paschke R.
    J Biol Chem; 2009 Jun 12; 284(24):16317-16324. PubMed ID: 19386596
    [Abstract] [Full Text] [Related]


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