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Journal Abstract Search

127 related items for PubMed ID: 9113339

  • 21. A Short Review on the Synthetic Strategies of Duocarmycin Analogs that are Powerful DNA Alkylating Agents.
    Patil PC, Satam V, Lee M.
    Anticancer Agents Med Chem; 2015; 15(5):616-30. PubMed ID: 25511515
    [Abstract] [Full Text] [Related]

  • 22. A fundamental relationship between hydrophobic properties and biological activity for the duocarmycin class of DNA-alkylating antitumor drugs: hydrophobic-binding-driven bonding.
    Wolfe AL, Duncan KK, Lajiness JP, Zhu K, Duerfeldt AS, Boger DL.
    J Med Chem; 2013 Sep 12; 56(17):6845-57. PubMed ID: 23944748
    [Abstract] [Full Text] [Related]

  • 23. Duocarmycins, new antitumor antibiotics produced by Streptomyces; producing organisms and improved production.
    Ichimura M, Ogawa T, Katsumata S, Takahashi K, Takahashi I, Nakano H.
    J Antibiot (Tokyo); 1991 Oct 12; 44(10):1045-53. PubMed ID: 1955385
    [Abstract] [Full Text] [Related]

  • 24. The effect of a bromide leaving group on the properties of nitro analogs of the duocarmycins as hypoxia-activated prodrugs and phosphate pre-prodrugs for antitumor therapy.
    Stevenson RJ, Denny WA, Ashoorzadeh A, Pruijn FB, van Leeuwen WF, Tercel M.
    Bioorg Med Chem; 2011 Oct 15; 19(20):5989-98. PubMed ID: 21920763
    [Abstract] [Full Text] [Related]

  • 25. The novel cyclopropapyrroloindole(CPI) bisalkylators bearing 3,3'-(1,4-phenylene)diacryloyl group as a linker.
    Fukuda Y, Seto S, Furuta H, Ebisu H, Oomori Y, Terashima S.
    Bioorg Med Chem Lett; 1998 Aug 04; 8(15):2003-4. PubMed ID: 9873475
    [Abstract] [Full Text] [Related]

  • 26. Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI) subunit of the antitumor agent CC-1065 and polypyrrole minor groove binders.
    Baraldi PG, Balboni G, Pavani MG, Spalluto G, Tabrizi MA, Clercq ED, Balzarini J, Bando T, Sugiyama H, Romagnoli R.
    J Med Chem; 2001 Aug 02; 44(16):2536-43. PubMed ID: 11472207
    [Abstract] [Full Text] [Related]

  • 27. Synthesis and evaluation of 1,2,8, 8a-Tetrahydrocyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one, the parent alkylation subunit of CC-1065 and the duocarmycins: impact of the alkylation subunit substituents and its implications for DNA alkylation catalysis.
    Boger DL, Santillán A, Searcey M, Brunette SR, Wolkenberg SE, Hedrick MP, Jin Q.
    J Org Chem; 2000 Jun 30; 65(13):4101-11. PubMed ID: 10866627
    [Abstract] [Full Text] [Related]

  • 28. The novel cyclopropapyrroloindole(CPI) bisalkylators bearing methoxycarbonyl and trifluoromethyl groups.
    Fukuda Y, Furuta H, Kusama Y, Ebisu H, Oomori Y, Terashima S.
    Bioorg Med Chem Lett; 1998 Jun 02; 8(11):1387-90. PubMed ID: 9871771
    [Abstract] [Full Text] [Related]

  • 29. A strategy for tumor-selective chemotherapy by enzymatic liberation of seco-duocarmycin SA-derivatives from nontoxic prodrugs.
    Tietze LF, Lieb M, Herzig T, Haunert F, Schuberth I.
    Bioorg Med Chem; 2001 Jul 02; 9(7):1929-39. PubMed ID: 11425596
    [Abstract] [Full Text] [Related]

  • 30. Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds.
    Amishiro N, Okamoto A, Murakata C, Tamaoki T, Okabe M, Saito H.
    J Med Chem; 1999 Jul 29; 42(15):2946-60. PubMed ID: 10425104
    [Abstract] [Full Text] [Related]

  • 31. High resolution solution structure of a DNA duplex alkylated by the antitumor agent duocarmycin SA.
    Eis PS, Smith JA, Rydzewski JM, Case DA, Boger DL, Chazin WJ.
    J Mol Biol; 1997 Sep 19; 272(2):237-52. PubMed ID: 9299351
    [Abstract] [Full Text] [Related]

  • 32. Alkylation of duplex DNA in nucleosome core particles by duocarmycin SA and yatakemycin.
    Trzupek JD, Gottesfeld JM, Boger DL.
    Nat Chem Biol; 2006 Feb 19; 2(2):79-82. PubMed ID: 16415862
    [Abstract] [Full Text] [Related]

  • 33. Novel seco cyclopropa[c]pyrrolo[3,2-e]indole bisalkylators bearing a 3,3'-arylenebisacryloyl group as a linker.
    Fukuda Y, Seto S, Furuta H, Ebisu H, Oomori Y, Terashima S.
    J Med Chem; 2001 Apr 26; 44(9):1396-406. PubMed ID: 11311062
    [Abstract] [Full Text] [Related]

  • 34. Metal cation complexation and activation of reversed CPyI analogues of CC-1065 and duocarmycin SA: partitioning the effects of binding and catalysis.
    Ellis DA, Wolkenberg SE, Boger DL.
    J Am Chem Soc; 2001 Sep 26; 123(38):9299-306. PubMed ID: 11562212
    [Abstract] [Full Text] [Related]

  • 35. The structural basis for in situ activation of DNA alkylation by duocarmycin SA.
    Smith JA, Bifulco G, Case DA, Boger DL, Gomez-Paloma L, Chazin WJ.
    J Mol Biol; 2000 Jul 28; 300(5):1195-204. PubMed ID: 10903864
    [Abstract] [Full Text] [Related]

  • 36. Design, synthesis, and evaluation of duocarmycin O-amino phenol prodrugs subject to tunable reductive activation.
    Lajiness JP, Robertson WM, Dunwiddie I, Broward MA, Vielhauer GA, Weir SJ, Boger DL.
    J Med Chem; 2010 Nov 11; 53(21):7731-8. PubMed ID: 20942408
    [Abstract] [Full Text] [Related]

  • 37. Anticellular and antitumor activity of duocarmycins, novel antitumor antibiotics.
    Gomi K, Kobayashi E, Miyoshi K, Ashizawa T, Okamoto A, Ogawa T, Katsumata S, Mihara A, Okabe M, Hirata T.
    Jpn J Cancer Res; 1992 Jan 11; 83(1):113-20. PubMed ID: 1544867
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