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399 related items for PubMed ID: 9115645

  • 1. Characterization of the adrenal cytochrome P450C17 in the hamster, a small animal model for the study of adrenal dehydroepiandrosterone biosynthesis.
    Cloutier M, Fleury A, Courtemanche J, Ducharme L, Mason JI, Lehoux JG.
    DNA Cell Biol; 1997 Mar; 16(3):357-68. PubMed ID: 9115645
    [Abstract] [Full Text] [Related]

  • 2. Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase.
    Swart P, Swart AC, Waterman MR, Estabrook RW, Mason JI.
    J Clin Endocrinol Metab; 1993 Jul; 77(1):98-102. PubMed ID: 8325965
    [Abstract] [Full Text] [Related]

  • 3. Molecular cloning and expression of guinea pig cytochrome P450c17 cDNA (steroid 17 alpha-hydroxylase/17,20 lyase): tissue distribution, regulation, and substrate specificity of the expressed enzyme.
    Tremblay Y, Fleury A, Beaudoin C, Vallée M, Bélanger A.
    DNA Cell Biol; 1994 Dec; 13(12):1199-212. PubMed ID: 7811386
    [Abstract] [Full Text] [Related]

  • 4. Occurrence of cytochrome P450c17 mRNA and dehydroepiandrosterone biosynthesis in the rat gastrointestinal tract.
    Dalla Valle L, Couët J, Labrie Y, Simard J, Belvedere P, Simontacchi C, Labrie F, Colombo L.
    Mol Cell Endocrinol; 1995 Apr 28; 111(1):83-92. PubMed ID: 7649357
    [Abstract] [Full Text] [Related]

  • 5. Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone.
    Soucy P, Luu-The V.
    Eur J Biochem; 2000 Jun 28; 267(11):3243-7. PubMed ID: 10824109
    [Abstract] [Full Text] [Related]

  • 6. Modulation of 17alpha-hydroxylase/17,20-lyase activity of guinea pig cytochrome P450c17 by site-directed mutagenesis.
    Beaudoin C, Lavallée B, Tremblay Y, Hum DW, Breton R, de Launoit Y, Bélanger A.
    DNA Cell Biol; 1998 Aug 28; 17(8):707-15. PubMed ID: 9726253
    [Abstract] [Full Text] [Related]

  • 7. Molecular evolution of adrenarche: structural and functional analysis of p450c17 from four primate species.
    Arlt W, Martens JW, Song M, Wang JT, Auchus RJ, Miller WL.
    Endocrinology; 2002 Dec 28; 143(12):4665-72. PubMed ID: 12446594
    [Abstract] [Full Text] [Related]

  • 8. The hamster adrenal cytochrome P450C11 has equipotent 11beta-hydroxylase and 19-hydroxylase activities, but no aldosterone synthase activity.
    Véronneau S, Bernard H, Cloutier M, Courtemanche J, Ducharme L, Lefebvre A, Mason JI, LeHoux JG.
    J Steroid Biochem Mol Biol; 1996 Jan 28; 57(1-2):125-39. PubMed ID: 8645611
    [Abstract] [Full Text] [Related]

  • 9. Isolation and characterization of the cDNA encoding the spiny dogfish shark (Squalus acanthias) form of cytochrome P450c17.
    Trant JM.
    J Exp Zool; 1995 May 01; 272(1):25-33. PubMed ID: 7738515
    [Abstract] [Full Text] [Related]

  • 10. Biochemical differences between rat and human cytochrome P450c17 support the different steroidogenic needs of these two species.
    Brock BJ, Waterman MR.
    Biochemistry; 1999 Feb 02; 38(5):1598-606. PubMed ID: 9931027
    [Abstract] [Full Text] [Related]

  • 11. Molecular modeling of the hamster adrenal P450C17.
    Mathieu AP, Auchus RJ, LeHoux JG.
    Endocr Res; 2000 Nov 02; 26(4):723-8. PubMed ID: 11196448
    [Abstract] [Full Text] [Related]

  • 12. The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway.
    Flück CE, Miller WL, Auchus RJ.
    J Clin Endocrinol Metab; 2003 Aug 02; 88(8):3762-6. PubMed ID: 12915666
    [Abstract] [Full Text] [Related]

  • 13. CYP17 mutation E305G causes isolated 17,20-lyase deficiency by selectively altering substrate binding.
    Sherbet DP, Tiosano D, Kwist KM, Hochberg Z, Auchus RJ.
    J Biol Chem; 2003 Dec 05; 278(49):48563-9. PubMed ID: 14504283
    [Abstract] [Full Text] [Related]

  • 14. Steroid 17 alpha-hydroxylase and 17,20-lyase activities of P450c17: contributions of serine106 and P450 reductase.
    Lin D, Black SM, Nagahama Y, Miller WL.
    Endocrinology; 1993 Jun 05; 132(6):2498-506. PubMed ID: 8504753
    [Abstract] [Full Text] [Related]

  • 15. Expression of bovine cytochrome P450c17 cDNA in Saccharomyces cerevisiae.
    Sakaki T, Shibata M, Yabusaki Y, Murakami H, Ohkawa H.
    DNA; 1989 Jun 05; 8(6):409-18. PubMed ID: 2673705
    [Abstract] [Full Text] [Related]

  • 16. Ontogeny of the adrenal gland in the spiny mouse, with particular reference to production of the steroids cortisol and dehydroepiandrosterone.
    Quinn TA, Ratnayake U, Dickinson H, Nguyen TH, McIntosh M, Castillo-Melendez M, Conley AJ, Walker DW.
    Endocrinology; 2013 Mar 05; 154(3):1190-201. PubMed ID: 23354096
    [Abstract] [Full Text] [Related]

  • 17. Cytochrome P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues.
    Chung BC, Picado-Leonard J, Haniu M, Bienkowski M, Hall PF, Shively JE, Miller WL.
    Proc Natl Acad Sci U S A; 1987 Jan 05; 84(2):407-11. PubMed ID: 3025870
    [Abstract] [Full Text] [Related]

  • 18. Dehydroepiandrosterone: biosynthesis and metabolism in the brain.
    Zwain IH, Yen SS.
    Endocrinology; 1999 Feb 05; 140(2):880-7. PubMed ID: 9927319
    [Abstract] [Full Text] [Related]

  • 19. A role for cytochrome P450 17alpha-hydroxylase/c17-20 lyase during shift in steroidogenesis occurring in ovarian follicles prior to oocyte maturation.
    Sreenivasulu G, Senthilkumaran B.
    J Steroid Biochem Mol Biol; 2009 Jul 05; 115(3-5):77-85. PubMed ID: 19500725
    [Abstract] [Full Text] [Related]

  • 20. Molecular dynamics of substrate complexes with hamster cytochrome P450c17 (CYP17): mechanistic approach to understanding substrate binding and activities.
    Mathieu AP, LeHoux JG, Auchus RJ.
    Biochim Biophys Acta; 2003 Feb 17; 1619(3):291-300. PubMed ID: 12573489
    [Abstract] [Full Text] [Related]

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