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Journal Abstract Search

142 related items for PubMed ID: 9115849

  • 1.
    ; . PubMed ID:
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  • 2. A mutant insulin receptor induces formation of a Shc-growth factor receptor bound protein 2 (Grb2) complex and p21ras-GTP without detectable interaction of insulin receptor substrate 1 (IRS1) with Grb2. Evidence for IRS1-independent p21ras-GTP formation.
    Ouwens DM, van der Zon GC, Pronk GJ, Bos JL, Möller W, Cheatham B, Kahn CR, Maassen JA.
    J Biol Chem; 1994 Dec 30; 269(52):33116-22. PubMed ID: 7806540
    [Abstract] [Full Text] [Related]

  • 3. Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation.
    Noguchi T, Matozaki T, Horita K, Fujioka Y, Kasuga M.
    Mol Cell Biol; 1994 Oct 30; 14(10):6674-82. PubMed ID: 7935386
    [Abstract] [Full Text] [Related]

  • 4. Insulin-induced egr-1 and c-fos expression in 32D cells requires insulin receptor, Shc, and mitogen-activated protein kinase, but not insulin receptor substrate-1 and phosphatidylinositol 3-kinase activation.
    Harada S, Smith RM, Smith JA, White MF, Jarett L.
    J Biol Chem; 1996 Nov 22; 271(47):30222-6. PubMed ID: 8939974
    [Abstract] [Full Text] [Related]

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  • 6. Insulin stimulates association of insulin receptor substrate-1 with the protein abundant Src homology/growth factor receptor-bound protein 2.
    Tobe K, Matuoka K, Tamemoto H, Ueki K, Kaburagi Y, Asai S, Noguchi T, Matsuda M, Tanaka S, Hattori S.
    J Biol Chem; 1993 May 25; 268(15):11167-71. PubMed ID: 8388384
    [Abstract] [Full Text] [Related]

  • 7. Insulin receptor substrate 1 rescues insulin action in CHO cells expressing mutant insulin receptors that lack a juxtamembrane NPXY motif.
    Chen D, Van Horn DJ, White MF, Backer JM.
    Mol Cell Biol; 1995 Sep 25; 15(9):4711-7. PubMed ID: 7651388
    [Abstract] [Full Text] [Related]

  • 8. Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes.
    Mur C, Valverde AM, Kahn CR, Benito M.
    Diabetes; 2002 Mar 25; 51(3):743-54. PubMed ID: 11872675
    [Abstract] [Full Text] [Related]

  • 9. Shc is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21ras-GTP formation.
    Sasaoka T, Draznin B, Leitner JW, Langlois WJ, Olefsky JM.
    J Biol Chem; 1994 Apr 08; 269(14):10734-8. PubMed ID: 8144662
    [Abstract] [Full Text] [Related]

  • 10. Two naturally occurring insulin receptor tyrosine kinase domain mutants provide evidence that phosphoinositide 3-kinase activation alone is not sufficient for the mediation of insulin's metabolic and mitogenic effects.
    Krook A, Whitehead JP, Dobson SP, Griffiths MR, Ouwens M, Baker C, Hayward AC, Sen SK, Maassen JA, Siddle K, Tavaré JM, O'Rahilly S.
    J Biol Chem; 1997 Nov 28; 272(48):30208-14. PubMed ID: 9374504
    [Abstract] [Full Text] [Related]

  • 11. PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model.
    Weng LP, Smith WM, Brown JL, Eng C.
    Hum Mol Genet; 2001 Mar 15; 10(6):605-16. PubMed ID: 11230180
    [Abstract] [Full Text] [Related]

  • 12. Alpha2-Heremans Schmid glycoprotein inhibits insulin-stimulated Elk-1 phosphorylation, but not glucose transport, in rat adipose cells.
    Chen H, Srinivas PR, Cong LN, Li Y, Grunberger G, Quon MJ.
    Endocrinology; 1998 Oct 15; 139(10):4147-54. PubMed ID: 9751494
    [Abstract] [Full Text] [Related]

  • 13. Serum alpha 2-HS-glycoprotein is an inhibitor of the human insulin receptor at the tyrosine kinase level.
    Srinivas PR, Wagner AS, Reddy LV, Deutsch DD, Leon MA, Goustin AS, Grunberger G.
    Mol Endocrinol; 1993 Nov 15; 7(11):1445-55. PubMed ID: 7906861
    [Abstract] [Full Text] [Related]

  • 14. A complex of GRB2-dynamin binds to tyrosine-phosphorylated insulin receptor substrate-1 after insulin treatment.
    Ando A, Yonezawa K, Gout I, Nakata T, Ueda H, Hara K, Kitamura Y, Noda Y, Takenawa T, Hirokawa N.
    EMBO J; 1994 Jul 01; 13(13):3033-8. PubMed ID: 8039498
    [Abstract] [Full Text] [Related]

  • 15. Role of IRS-1-GRB-2 complexes in insulin signaling.
    Myers MG, Wang LM, Sun XJ, Zhang Y, Yenush L, Schlessinger J, Pierce JH, White MF.
    Mol Cell Biol; 1994 Jun 01; 14(6):3577-87. PubMed ID: 8196603
    [Abstract] [Full Text] [Related]

  • 16. Alpha2-HSG, a specific inhibitor of insulin receptor autophosphorylation, interacts with the insulin receptor.
    Mathews ST, Chellam N, Srinivas PR, Cintron VJ, Leon MA, Goustin AS, Grunberger G.
    Mol Cell Endocrinol; 2000 Jun 01; 164(1-2):87-98. PubMed ID: 11026561
    [Abstract] [Full Text] [Related]

  • 17. Morphine induces desensitization of insulin receptor signaling.
    Li Y, Eitan S, Wu J, Evans CJ, Kieffer B, Sun X, Polakiewicz RD.
    Mol Cell Biol; 2003 Sep 01; 23(17):6255-66. PubMed ID: 12917346
    [Abstract] [Full Text] [Related]

  • 18. Comparison of the insulin and insulin-like growth factor 1 mitogenic intracellular signaling pathways.
    Sasaoka T, Ishiki M, Sawa T, Ishihara H, Takata Y, Imamura T, Usui I, Olefsky JM, Kobayashi M.
    Endocrinology; 1996 Oct 01; 137(10):4427-34. PubMed ID: 8828504
    [Abstract] [Full Text] [Related]

  • 19. Insulin stimulation of a MEK-dependent but ERK-independent SOS protein kinase.
    Holt KH, Kasson BG, Pessin JE.
    Mol Cell Biol; 1996 Feb 01; 16(2):577-83. PubMed ID: 8552085
    [Abstract] [Full Text] [Related]

  • 20. Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and phosphoinositide 3-kinase-dependent signalling.
    Ahmed Z, Pillay TS.
    Biochem J; 2003 Apr 15; 371(Pt 2):405-12. PubMed ID: 12521378
    [Abstract] [Full Text] [Related]

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