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441 related items for PubMed ID: 9122164

  • 1. The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins.
    Pause A, Lee S, Worrell RA, Chen DY, Burgess WH, Linehan WM, Klausner RD.
    Proc Natl Acad Sci U S A; 1997 Mar 18; 94(6):2156-61. PubMed ID: 9122164
    [Abstract] [Full Text] [Related]

  • 2. Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex.
    Iwai K, Yamanaka K, Kamura T, Minato N, Conaway RC, Conaway JW, Klausner RD, Pause A.
    Proc Natl Acad Sci U S A; 1999 Oct 26; 96(22):12436-41. PubMed ID: 10535940
    [Abstract] [Full Text] [Related]

  • 3. The von Hippel-Lindau tumor suppressor gene product promotes, but is not essential for, NEDD8 conjugation to cullin-2.
    Wada H, Yeh ET, Kamitani T.
    J Biol Chem; 1999 Dec 10; 274(50):36025-9. PubMed ID: 10585493
    [Abstract] [Full Text] [Related]

  • 4. The von Hippel-Lindau tumour suppressor protein: new perspectives.
    Ohh M, Kaelin WG.
    Mol Med Today; 1999 Jun 10; 5(6):257-63. PubMed ID: 10366821
    [Abstract] [Full Text] [Related]

  • 5. Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
    Kamura T, Koepp DM, Conrad MN, Skowyra D, Moreland RJ, Iliopoulos O, Lane WS, Kaelin WG, Elledge SJ, Conaway RC, Harper JW, Conaway JW.
    Science; 1999 Apr 23; 284(5414):657-61. PubMed ID: 10213691
    [Abstract] [Full Text] [Related]

  • 6. Diverse effects of mutations in exon II of the von Hippel-Lindau (VHL) tumor suppressor gene on the interaction of pVHL with the cytosolic chaperonin and pVHL-dependent ubiquitin ligase activity.
    Hansen WJ, Ohh M, Moslehi J, Kondo K, Kaelin WG, Welch WJ.
    Mol Cell Biol; 2002 Mar 23; 22(6):1947-60. PubMed ID: 11865071
    [Abstract] [Full Text] [Related]

  • 7. Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C.
    Kibel A, Iliopoulos O, DeCaprio JA, Kaelin WG.
    Science; 1995 Sep 08; 269(5229):1444-6. PubMed ID: 7660130
    [Abstract] [Full Text] [Related]

  • 8. Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein.
    Pause A, Peterson B, Schaffar G, Stearman R, Klausner RD.
    Proc Natl Acad Sci U S A; 1999 Aug 17; 96(17):9533-8. PubMed ID: 10449727
    [Abstract] [Full Text] [Related]

  • 9. Identification of elongin C sequences required for interaction with the von Hippel-Lindau tumor suppressor protein.
    Takagi Y, Pause A, Conaway RC, Conaway JW.
    J Biol Chem; 1997 Oct 24; 272(43):27444-9. PubMed ID: 9341197
    [Abstract] [Full Text] [Related]

  • 10. The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma.
    Clifford SC, Astuti D, Hooper L, Maxwell PH, Ratcliffe PJ, Maher ER.
    Oncogene; 2001 Aug 16; 20(36):5067-74. PubMed ID: 11526493
    [Abstract] [Full Text] [Related]

  • 11. Identification of a novel protein (VBP-1) binding to the von Hippel-Lindau (VHL) tumor suppressor gene product.
    Tsuchiya H, Iseda T, Hino O.
    Cancer Res; 1996 Jul 01; 56(13):2881-5. PubMed ID: 8674032
    [Abstract] [Full Text] [Related]

  • 12. Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease.
    Zatyka M, da Silva NF, Clifford SC, Morris MR, Wiesener MS, Eckardt KU, Houlston RS, Richards FM, Latif F, Maher ER.
    Cancer Res; 2002 Jul 01; 62(13):3803-11. PubMed ID: 12097293
    [Abstract] [Full Text] [Related]

  • 13. The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity.
    Lisztwan J, Imbert G, Wirbelauer C, Gstaiger M, Krek W.
    Genes Dev; 1999 Jul 15; 13(14):1822-33. PubMed ID: 10421634
    [Abstract] [Full Text] [Related]

  • 14. Ubiquitination of a novel deubiquitinating enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein.
    Li Z, Na X, Wang D, Schoen SR, Messing EM, Wu G.
    J Biol Chem; 2002 Feb 15; 277(7):4656-62. PubMed ID: 11739384
    [Abstract] [Full Text] [Related]

  • 15. Alternate choice of initiation codon produces a biologically active product of the von Hippel Lindau gene with tumor suppressor activity.
    Blankenship C, Naglich JG, Whaley JM, Seizinger B, Kley N.
    Oncogene; 1999 Feb 25; 18(8):1529-35. PubMed ID: 10102622
    [Abstract] [Full Text] [Related]

  • 16. Characterization of the VHL tumor suppressor gene product: localization, complex formation, and the effect of natural inactivating mutations.
    Duan DR, Humphrey JS, Chen DY, Weng Y, Sukegawa J, Lee S, Gnarra JR, Linehan WM, Klausner RD.
    Proc Natl Acad Sci U S A; 1995 Jul 03; 92(14):6459-63. PubMed ID: 7604013
    [Abstract] [Full Text] [Related]

  • 17. Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2.
    Lonergan KM, Iliopoulos O, Ohh M, Kamura T, Conaway RC, Conaway JW, Kaelin WG.
    Mol Cell Biol; 1998 Feb 03; 18(2):732-41. PubMed ID: 9447969
    [Abstract] [Full Text] [Related]

  • 18. Elongin BC complex prevents degradation of von Hippel-Lindau tumor suppressor gene products.
    Schoenfeld AR, Davidowitz EJ, Burk RD.
    Proc Natl Acad Sci U S A; 2000 Jul 18; 97(15):8507-12. PubMed ID: 10900011
    [Abstract] [Full Text] [Related]

  • 19. Conjugation of the ubiquitin-like protein NEDD8 to cullin-2 is linked to von Hippel-Lindau tumor suppressor function.
    Liakopoulos D, Büsgen T, Brychzy A, Jentsch S, Pause A.
    Proc Natl Acad Sci U S A; 1999 May 11; 96(10):5510-5. PubMed ID: 10318914
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of transcription elongation by the VHL tumor suppressor protein.
    Duan DR, Pause A, Burgess WH, Aso T, Chen DY, Garrett KP, Conaway RC, Conaway JW, Linehan WM, Klausner RD.
    Science; 1995 Sep 08; 269(5229):1402-6. PubMed ID: 7660122
    [Abstract] [Full Text] [Related]

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