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208 related items for PubMed ID: 9135034

  • 1. Bioactivities and secondary structures of constrained analogues of human parathyroid hormone: cyclic lactams of the receptor binding region.
    Barbier JR, Neugebauer W, Morley P, Ross V, Soska M, Whitfield JF, Willick G.
    J Med Chem; 1997 Apr 25; 40(9):1373-80. PubMed ID: 9135034
    [Abstract] [Full Text] [Related]

  • 2. Cyclization by a specific lactam increases the ability of human parathyroid hormone (hPTH)-(1-31)NH2 to stimulate bone growth in ovariectomized rats.
    Whitfield JF, Morley P, Willick G, Langille R, Ross V, MacLean S, Barbier JR.
    J Bone Miner Res; 1997 Aug 25; 12(8):1246-52. PubMed ID: 9258755
    [Abstract] [Full Text] [Related]

  • 3. Lactam formation increases receptor binding, adenylyl cyclase stimulation and bone growth stimulation by human parathyroid hormone (hPTH)(1-28)NH2.
    Whitfield JF, Morley P, Willick GE, Isaacs RJ, MacLean S, Ross V, Barbier JR, Divieti P, Bringhurst FR.
    J Bone Miner Res; 2000 May 25; 15(5):964-70. PubMed ID: 10804028
    [Abstract] [Full Text] [Related]

  • 4. Structure and protein kinase C stimulating activities of lactam analogues of human parathyroid hormone fragment.
    Neugebauer W, Gagnon L, Whitfield J, Willick GE.
    Int J Pept Protein Res; 1994 Jun 25; 43(6):555-62. PubMed ID: 7928086
    [Abstract] [Full Text] [Related]

  • 5. The effect of monocyclic and bicyclic analogs of human parathyroid hormone (hPTH)-(1-31)NH2 on bone formation and mechanical strength in ovariectomized rats.
    Morley P, Whitfield JF, Willick GE, Ross V, MacLean S, Barbier JR, Isaacs RJ, Andreassen TT.
    Calcif Tissue Int; 2001 Feb 25; 68(2):95-101. PubMed ID: 11310353
    [Abstract] [Full Text] [Related]

  • 6. Mono- and bicyclic analogs of parathyroid hormone-related protein. 1. Synthesis and biological studies.
    Bisello A, Nakamoto C, Rosenblatt M, Chorev M.
    Biochemistry; 1997 Mar 18; 36(11):3293-9. PubMed ID: 9116007
    [Abstract] [Full Text] [Related]

  • 7. Structure and activities of constrained analogues of human parathyroid hormone and parathyroid hormone-related peptide: implications for receptor-activating conformations of the hormones.
    Barbier JR, MacLean S, Morley P, Whitfield JF, Willick GE.
    Biochemistry; 2000 Nov 28; 39(47):14522-30. PubMed ID: 11087406
    [Abstract] [Full Text] [Related]

  • 8. Stimulation of protein kinase C activity in cells expressing human parathyroid hormone receptors by C- and N-terminally truncated fragments of parathyroid hormone 1-34.
    Whitfield JF, Isaacs RJ, Chakravarthy B, Maclean S, Morley P, Willick G, Divieti P, Bringhurst FR.
    J Bone Miner Res; 2001 Mar 28; 16(3):441-7. PubMed ID: 11277261
    [Abstract] [Full Text] [Related]

  • 9. C-terminal analogues of parathyroid hormone: effect of C-terminus function on helical structure, stability, and bioactivity.
    Potetinova Z, Barbier JR, Suen T, Dean T, Gardella TJ, Willick GE.
    Biochemistry; 2006 Sep 19; 45(37):11113-21. PubMed ID: 16964972
    [Abstract] [Full Text] [Related]

  • 10. Human growth hormone-releasing hormone hGHRH(1-29)-NH2: systematic structure-activity relationship studies.
    Cervini LA, Donaldson CJ, Koerber SC, Vale WW, Rivier JE.
    J Med Chem; 1998 Feb 26; 41(5):717-27. PubMed ID: 9513600
    [Abstract] [Full Text] [Related]

  • 11. Functional properties of a synthetic chicken parathyroid hormone-related protein 1-36 fragment.
    Schermer DT, Bradley MS, Bambino TH, Nissenson RA, Strewler GJ.
    J Bone Miner Res; 1994 Jul 26; 9(7):1041-6. PubMed ID: 7942150
    [Abstract] [Full Text] [Related]

  • 12. Comparison of the abilities of human parathyroid hormone (hPTH)-(1-34) and [Leu27]-cyclo(Glu22-Lys26)-hPTH-(1-31)NH2 to stimulate femoral trabecular bone growth in ovariectomized rats.
    Whitfield JF, Morley P, Willick G, MacLean S, Ross V, Isaacs RJ, Barbier JR.
    Calcif Tissue Int; 1998 Nov 26; 63(5):423-8. PubMed ID: 9799828
    [Abstract] [Full Text] [Related]

  • 13. Mono- and bicyclic analogs of parathyroid hormone-related protein. 2. Conformational analysis of antagonists by CD, NMR, and distance geometry calculations.
    Maretto S, Mammi S, Bissacco E, Peggion E, Bisello A, Rosenblatt M, Chorev M, Mierke DF.
    Biochemistry; 1997 Mar 18; 36(11):3300-7. PubMed ID: 9116008
    [Abstract] [Full Text] [Related]

  • 14. The stimulation of vertebral and tibial bone growth by the parathyroid hormone fragments, hPTH-(1-31)NH2, [Leu27]cyclo(Glu22-Lys26)hPTH-(1-31)NH2, and hPTH-(1-30)NH2.
    Whitfield JF, Morley P, Fraher L, Hodsman AB, Holdsworth DW, Watson PH, Willick GE, Barbier JR, Gulam M, Isaacs RJ, MacLean S, Ross V.
    Calcif Tissue Int; 2000 Apr 18; 66(4):307-12. PubMed ID: 10742450
    [Abstract] [Full Text] [Related]

  • 15. Stimulation of membrane-associated protein kinase-C activity in spleen lymphocytes by hPTH-(1-31)NH2, its lactam derivative, [Leu27]-cyclo(Glu22-Lys26)-hPTH-(1-31)NH2, and hPTH-(1-30)NH2.
    Whitfield JF, Isaacs R, MacLean S, Morley P, Barbier JR, Willick GE.
    Cell Signal; 1999 Mar 18; 11(3):159-64. PubMed ID: 10353689
    [Abstract] [Full Text] [Related]

  • 16. Solution structure and adenylyl cyclase stimulating activities of C-terminal truncated human parathyroid hormone analogues.
    Neugebauer W, Barbier JR, Sung WL, Whitfield JF, Willick GE.
    Biochemistry; 1995 Jul 11; 34(27):8835-42. PubMed ID: 7612624
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis, and biological activities of cyclic lactam peptide analogues of dynorphine A(1-11)-NH2.
    Lung FD, Collins N, Stropova D, Davis P, Yamamura HI, Porreca F, Hruby VJ.
    J Med Chem; 1996 Mar 01; 39(5):1136-41. PubMed ID: 8676350
    [Abstract] [Full Text] [Related]

  • 18. Functional evidence for an intramolecular side chain interaction between residues 6 and 10 of receptor-bound parathyroid hormone analogues.
    Shimizu N, Petroni BD, Khatri A, Gardella TJ.
    Biochemistry; 2003 Mar 04; 42(8):2282-90. PubMed ID: 12600195
    [Abstract] [Full Text] [Related]

  • 19. Side chain cyclization based on serine residues: synthesis, structure, and activity of a novel cyclic analogue of the parathyroid hormone fragment 1-11.
    Caporale A, Sturlese M, Gesiot L, Zanta F, Wittelsberger A, Cabrele C.
    J Med Chem; 2010 Nov 25; 53(22):8072-9. PubMed ID: 21028829
    [Abstract] [Full Text] [Related]

  • 20. Toward parathyroid hormone minimization: conformational studies of cyclic PTH(1-14) analogues.
    Tsomaia N, Pellegrini M, Hyde K, Gardella TJ, Mierke DF.
    Biochemistry; 2004 Jan 27; 43(3):690-9. PubMed ID: 14730973
    [Abstract] [Full Text] [Related]

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