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169 related items for PubMed ID: 9139749

  • 21. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
    Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB.
    Proc Natl Acad Sci U S A; 2001 Apr 10; 98(8):4640-5. PubMed ID: 11287630
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  • 22. Multiple signaling pathways mediate interleukin-4-induced 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase type 1 gene expression in human breast cancer cells.
    Gingras S, Côté S, Simard J.
    Mol Endocrinol; 2000 Feb 10; 14(2):229-40. PubMed ID: 10674396
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  • 23. 4PS/insulin receptor substrate (IRS)-2 is the alternative substrate of the insulin receptor in IRS-1-deficient mice.
    Patti ME, Sun XJ, Bruening JC, Araki E, Lipes MA, White MF, Kahn CR.
    J Biol Chem; 1995 Oct 20; 270(42):24670-3. PubMed ID: 7559579
    [Abstract] [Full Text] [Related]

  • 24. Effect of aging on insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of rats.
    Carvalho CR, Brenelli SL, Silva AC, Nunes AL, Velloso LA, Saad MJ.
    Endocrinology; 1996 Jan 20; 137(1):151-9. PubMed ID: 8536607
    [Abstract] [Full Text] [Related]

  • 25. Insulin-stimulated phosphatidylinositol 3-kinase. Association with a 185-kDa tyrosine-phosphorylated protein (IRS-1) and localization in a low density membrane vesicle.
    Kelly KL, Ruderman NB.
    J Biol Chem; 1993 Feb 25; 268(6):4391-8. PubMed ID: 8382701
    [Abstract] [Full Text] [Related]

  • 26. Cross-talk between the insulin and angiotensin signaling systems.
    Velloso LA, Folli F, Sun XJ, White MF, Saad MJ, Kahn CR.
    Proc Natl Acad Sci U S A; 1996 Oct 29; 93(22):12490-5. PubMed ID: 8901609
    [Abstract] [Full Text] [Related]

  • 27. Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1.
    Argetsinger LS, Hsu GW, Myers MG, Billestrup N, White MF, Carter-Su C.
    J Biol Chem; 1995 Jun 16; 270(24):14685-92. PubMed ID: 7782332
    [Abstract] [Full Text] [Related]

  • 28. Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus.
    Folli F, Saad MJ, Backer JM, Kahn CR.
    J Clin Invest; 1993 Oct 16; 92(4):1787-94. PubMed ID: 7691886
    [Abstract] [Full Text] [Related]

  • 29. Different pathways of postreceptor desensitization following chronic insulin treatment and in cells overexpressing constitutively active insulin receptors.
    Inoue G, Cheatham B, Kahn CR.
    J Biol Chem; 1996 Nov 08; 271(45):28206-11. PubMed ID: 8910437
    [Abstract] [Full Text] [Related]

  • 30. Insulin receptor substrate 2 and Shc play different roles in insulin-like growth factor I signaling.
    Kim B, Cheng HL, Margolis B, Feldman EL.
    J Biol Chem; 1998 Dec 18; 273(51):34543-50. PubMed ID: 9852124
    [Abstract] [Full Text] [Related]

  • 31. Islet transplantation restores normal levels of insulin receptor and substrate tyrosine phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle and myocardium of streptozocin-induced diabetic rats.
    Giorgino F, Logoluso F, Davalli AM, Napoli R, Laviola L, Hirshman MF, Horton ES, Weir GC, Smith RJ.
    Diabetes; 1999 Apr 18; 48(4):801-12. PubMed ID: 10102697
    [Abstract] [Full Text] [Related]

  • 32. Platelet-derived growth factor inhibits insulin stimulation of insulin receptor substrate-1-associated phosphatidylinositol 3-kinase in 3T3-L1 adipocytes without affecting glucose transport.
    Staubs PA, Nelson JG, Reichart DR, Olefsky JM.
    J Biol Chem; 1998 Sep 25; 273(39):25139-47. PubMed ID: 9737973
    [Abstract] [Full Text] [Related]

  • 33. Tyrosine phosphorylation of insulin receptor substrate-1 (IRS-1) by oxidant stress in cerebellar granule neurons: modulation by N-methyl-D-aspartate through calcineurin activity.
    Hallak H, Ramadan B, Rubin R.
    J Neurochem; 2001 Apr 25; 77(1):63-70. PubMed ID: 11279262
    [Abstract] [Full Text] [Related]

  • 34. Stimulation of C2C12 myoblast growth by basic fibroblast growth factor and insulin-like growth factor 1 can occur via mitogen-activated protein kinase-dependent and -independent pathways.
    Milasincic DJ, Calera MR, Farmer SR, Pilch PF.
    Mol Cell Biol; 1996 Nov 25; 16(11):5964-73. PubMed ID: 8887626
    [Abstract] [Full Text] [Related]

  • 35. Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins.
    Liu YF, Paz K, Herschkovitz A, Alt A, Tennenbaum T, Sampson SR, Ohba M, Kuroki T, LeRoith D, Zick Y.
    J Biol Chem; 2001 Apr 27; 276(17):14459-65. PubMed ID: 11278339
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  • 36. Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function.
    Paz K, Liu YF, Shorer H, Hemi R, LeRoith D, Quan M, Kanety H, Seger R, Zick Y.
    J Biol Chem; 1999 Oct 01; 274(40):28816-22. PubMed ID: 10497255
    [Abstract] [Full Text] [Related]

  • 37. Regulation of phosphatidylinositol 3'-kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85-kDa regulatory subunit.
    Rordorf-Nikolic T, Van Horn DJ, Chen D, White MF, Backer JM.
    J Biol Chem; 1995 Feb 24; 270(8):3662-6. PubMed ID: 7876105
    [Abstract] [Full Text] [Related]

  • 38. Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects.
    Goodyear LJ, Giorgino F, Sherman LA, Carey J, Smith RJ, Dohm GL.
    J Clin Invest; 1995 May 24; 95(5):2195-204. PubMed ID: 7537758
    [Abstract] [Full Text] [Related]

  • 39. Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.
    Batty IH, Fleming IN, Downes CP.
    Biochem J; 2004 May 01; 379(Pt 3):641-51. PubMed ID: 14769130
    [Abstract] [Full Text] [Related]

  • 40. Shp2 is required for protein kinase C-dependent phosphorylation of serine 307 in insulin receptor substrate-1.
    Müssig K, Staiger H, Fiedler H, Moeschel K, Beck A, Kellerer M, Häring HU.
    J Biol Chem; 2005 Sep 23; 280(38):32693-9. PubMed ID: 16055440
    [Abstract] [Full Text] [Related]

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