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761 related items for PubMed ID: 9144458

  • 1. Cytochrome P450 inactivation during reductive metabolism of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) by phenobarbital- and pyridine-induced rat liver microsomes.
    Ferrara R, Tolando R, King LJ, Manno M.
    Toxicol Appl Pharmacol; 1997 Apr; 143(2):420-8. PubMed ID: 9144458
    [Abstract] [Full Text] [Related]

  • 2. Reductive activation of 1,1-dichloro-1-fluoroethane (HCFC-141b) by phenobarbital- and pyridine-induced rat liver microsomal cytochrome P450.
    Tolando R, Ferrara R, Eldirdiri NI, Albores A, King LJ, Manno M.
    Xenobiotica; 1996 Apr; 26(4):425-35. PubMed ID: 9173683
    [Abstract] [Full Text] [Related]

  • 3. The role of cytochrome P450 2E1 in the species-dependent biotransformation of 1,2-dichloro-1,1,2-trifluoroethane in rats and mice.
    Dekant W, Assmann M, Urban G.
    Toxicol Appl Pharmacol; 1995 Dec; 135(2):200-7. PubMed ID: 8545828
    [Abstract] [Full Text] [Related]

  • 4. Reductive activation of HCFC-123 by methaemalbumin.
    Zanovello A, Ferrara R, Manno M.
    Toxicol Lett; 2003 Sep 15; 144(1):127-36. PubMed ID: 12919730
    [Abstract] [Full Text] [Related]

  • 5. Bioactivation to free radicals and cytotoxicity of 1,1-dichloro-1-fluoroethane (HCFC-141b).
    Zanovello A, Tolando R, Ferrara R, Bortolato S, Manno M.
    Xenobiotica; 2001 Feb 15; 31(2):99-112. PubMed ID: 11407538
    [Abstract] [Full Text] [Related]

  • 6. Metabolism of 1,2-dichloro-1-fluoroethane and 1-fluoro-1,2,2-trichloroethane: electronic factors govern the regioselectivity of cytochrome P450-dependent oxidation.
    Yin H, Anders MW, Jones JP.
    Chem Res Toxicol; 1996 Feb 15; 9(1):50-7. PubMed ID: 8924616
    [Abstract] [Full Text] [Related]

  • 7. Bioactivation and toxicity in vitro of HCFC-123 and HCFC-141b: role of cytochrome P450.
    Zanovello A, Ferrara R, Tolando R, Bortolato S, White IN, Manno M.
    Toxicol Lett; 2001 Oct 15; 124(1-3):139-52. PubMed ID: 11684366
    [Abstract] [Full Text] [Related]

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  • 9. Microsomal oxidation of N,N-diethylformamide and its effect on P450-dependent monooxygenases in rat liver.
    Amato G, Longo V, Mazzaccaro A, Gervasi PG.
    Chem Res Toxicol; 1996 Oct 15; 9(5):882-90. PubMed ID: 8828925
    [Abstract] [Full Text] [Related]

  • 10. Bioactivation and cytotoxicity of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) in isolated rat hepatocytes.
    Ferrara R, Zanovello A, Bortolato S, White IN, Manno M.
    Pharmacol Toxicol; 2001 Apr 15; 88(4):192-7. PubMed ID: 11322177
    [Abstract] [Full Text] [Related]

  • 11. Conditions influencing the rat liver microsomal metabolism of 2,2,-dichloro-1,1,1-trifluoroethane (HCFC-123).
    Godin CS, Drerup JM, Vinegar A.
    Drug Metab Dispos; 1993 Apr 15; 21(3):551-3. PubMed ID: 8100516
    [No Abstract] [Full Text] [Related]

  • 12. Metabolic oxidation and toxification of N-methylformamide catalyzed by the cytochrome P450 isoenzyme CYP2E1.
    Hyland R, Gescher A, Thummel K, Schiller C, Jheeta P, Mynett K, Smith AW, Mráz J.
    Mol Pharmacol; 1992 Feb 15; 41(2):259-66. PubMed ID: 1538706
    [Abstract] [Full Text] [Related]

  • 13. Differences in cytochrome P450-mediated biotransformation of 1,2-dichlorobenzene by rat and man: implications for human risk assessment.
    Hissink AM, Oudshoorn MJ, Van Ommen B, Haenen GR, Van Bladeren PJ.
    Chem Res Toxicol; 1996 Dec 15; 9(8):1249-56. PubMed ID: 8951226
    [Abstract] [Full Text] [Related]

  • 14. Metabolism in vivo and in vitro of the refrigerant substitute 1,1,1,2-tetrafluoro-2-chloroethane.
    Olson MJ, Johnson JT, O'Gara JF, Surbrook SE.
    Drug Metab Dispos; 1991 Dec 15; 19(5):1004-11. PubMed ID: 1686224
    [Abstract] [Full Text] [Related]

  • 15. Reductive metabolism of halothane by cytochrome P450 isoforms in rats and humans.
    Chow T, Imaoka S, Hiroi T, Funae Y.
    Res Commun Mol Pathol Pharmacol; 1996 Sep 15; 93(3):363-74. PubMed ID: 8896047
    [Abstract] [Full Text] [Related]

  • 16. The kidney as a novel target tissue for protein adduct formation associated with metabolism of halothane and the candidate chlorofluorocarbon replacement 2,2-dichloro-1,1,1-trifluoroethane.
    Huwyler J, Aeschlimann D, Christen U, Gut J.
    Eur J Biochem; 1992 Jul 01; 207(1):229-38. PubMed ID: 1628651
    [Abstract] [Full Text] [Related]

  • 17. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug 01; (59):1-66, A1-E7. PubMed ID: 11803702
    [Abstract] [Full Text] [Related]

  • 18. Activation of microsomal glutathione S-transferase and inhibition of cytochrome P450 1A1 activity as a model system for detecting protein alkylation by thiourea-containing compounds in rat liver microsomes.
    Onderwater RC, Commandeur JN, Menge WM, Vermeulen NP.
    Chem Res Toxicol; 1999 May 01; 12(5):396-402. PubMed ID: 10328749
    [Abstract] [Full Text] [Related]

  • 19. Interaction of constitutive and phenobarbital-induced cytochrome P-450 isozymes during the sequential oxidation of benzphetamine. Explanation for the difference in benzphetamine-induced hydrogen peroxide production and 455-nm complex formation in microsomes from untreated and phenobarbital-treated rats.
    Jeffery EH, Mannering GJ.
    Mol Pharmacol; 1983 May 01; 23(3):748-57. PubMed ID: 6865917
    [Abstract] [Full Text] [Related]

  • 20. Evidence for the stability and cytochrome P450 specificity of the phenobarbital-induced reductive halothane-cytochrome P450 complex formed in rat hepatic microsomes.
    Baker MT, Vasquez MT, Chiang CK.
    Biochem Pharmacol; 1991 Jun 01; 41(11):1691-9. PubMed ID: 2043158
    [Abstract] [Full Text] [Related]

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