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Journal Abstract Search

379 related items for PubMed ID: 9145922

  • 1. Two tyrosine residues on the alpha subunit are crucial for benzodiazepine binding and allosteric modulation of gamma-aminobutyric acidA receptors.
    Amin J, Brooks-Kayal A, Weiss DS.
    Mol Pharmacol; 1997 May; 51(5):833-41. PubMed ID: 9145922
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  • 2. A point mutation in the gamma2 subunit of gamma-aminobutyric acid type A receptors results in altered benzodiazepine binding site specificity.
    Buhr A, Sigel E.
    Proc Natl Acad Sci U S A; 1997 Aug 05; 94(16):8824-9. PubMed ID: 9238062
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  • 3. Molecular dissection of benzodiazepine binding and allosteric coupling using chimeric gamma-aminobutyric acidA receptor subunits.
    Boileau AJ, Kucken AM, Evers AR, Czajkowski C.
    Mol Pharmacol; 1998 Feb 05; 53(2):295-303. PubMed ID: 9463488
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  • 4. Residues at positions 206 and 209 of the alpha1 subunit of gamma-aminobutyric AcidA receptors influence affinities for benzodiazepine binding site ligands.
    Buhr A, Schaerer MT, Baur R, Sigel E.
    Mol Pharmacol; 1997 Oct 05; 52(4):676-82. PubMed ID: 9380031
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  • 5. Tyrosine 62 of the gamma-aminobutyric acid type A receptor beta 2 subunit is an important determinant of high affinity agonist binding.
    Newell JG, Davies M, Bateson AN, Dunn SM.
    J Biol Chem; 2000 May 12; 275(19):14198-204. PubMed ID: 10799496
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  • 6. Identification of benzodiazepine binding site residues in the gamma2 subunit of the gamma-aminobutyric acid(A) receptor.
    Kucken AM, Wagner DA, Ward PR, Teissére JA, Boileau AJ, Czajkowski C.
    Mol Pharmacol; 2000 May 12; 57(5):932-9. PubMed ID: 10779376
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  • 7. Structural elements of the gamma-aminobutyric acid type A receptor conferring subtype selectivity for benzodiazepine site ligands.
    Renard S, Olivier A, Granger P, Avenet P, Graham D, Sevrin M, George P, Besnard F.
    J Biol Chem; 1999 May 07; 274(19):13370-4. PubMed ID: 10224099
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  • 9. Identification of amino acid residues responsible for the alpha5 subunit binding selectivity of L-655,708, a benzodiazepine binding site ligand at the GABA(A) receptor.
    Casula MA, Bromidge FA, Pillai GV, Wingrove PB, Martin K, Maubach K, Seabrook GR, Whiting PJ, Hadingham KL.
    J Neurochem; 2001 Apr 07; 77(2):445-51. PubMed ID: 11299307
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  • 10. Probing the molecular basis for affinity/potency- and efficacy-based subtype-selectivity exhibited by benzodiazepine-site modulators at GABAA receptors.
    Söderhielm PC, Balle T, Bak-Nyhus S, Zhang M, Hansen KM, Ahring PK, Jensen AA.
    Biochem Pharmacol; 2018 Dec 07; 158():339-358. PubMed ID: 30121248
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  • 12. Alterations of the benzodiazepine site of rat alpha 6 beta 2 gamma 2-GABAA receptor by replacement of several divergent amino-terminal regions with the alpha 1 counterparts.
    Im WB, Pregenzer JF, Binder JA, Alberts GL, Im HK.
    Br J Pharmacol; 1997 Feb 07; 120(4):559-64. PubMed ID: 9051290
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  • 15. Identification of transduction elements for benzodiazepine modulation of the GABA(A) receptor: three residues are required for allosteric coupling.
    Boileau AJ, Czajkowski C.
    J Neurosci; 1999 Dec 01; 19(23):10213-20. PubMed ID: 10575018
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  • 16. The F-loop of the GABA A receptor gamma2 subunit contributes to benzodiazepine modulation.
    Padgett CL, Lummis SC.
    J Biol Chem; 2008 Feb 01; 283(5):2702-8. PubMed ID: 17974564
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  • 17. A (beta)-strand in the (gamma)2 subunit lines the benzodiazepine binding site of the GABA A receptor: structural rearrangements detected during channel gating.
    Teissére JA, Czajkowski C.
    J Neurosci; 2001 Jul 15; 21(14):4977-86. PubMed ID: 11438573
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  • 18. Pharmacological subtypes of the gamma-aminobutyric acidA receptors defined by a gamma-aminobutyric acid analogue 4,5,6,7-tetrahydroisoxazolo[5,4-c] pyridin-3-ol and allosteric coupling: characterization using subunit-specific antibodies.
    Huh KH, Delorey TM, Endo S, Olsen RW.
    Mol Pharmacol; 1995 Oct 15; 48(4):666-75. PubMed ID: 7476892
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  • 19. Point mutations of the alpha 1 beta 2 gamma 2 gamma-aminobutyric acid(A) receptor affecting modulation of the channel by ligands of the benzodiazepine binding site.
    Buhr A, Baur R, Malherbe P, Sigel E.
    Mol Pharmacol; 1996 Jun 15; 49(6):1080-4. PubMed ID: 8649346
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