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Journal Abstract Search

281 related items for PubMed ID: 9154971

  • 21. Sulfamide antifolates inhibiting thymidylate synthase: synthesis, enzyme inhibition and cytotoxicity.
    Pawełczak K, Makowski M, Kempny M, Dzik JM, Gołos B, Rode W, Rzeszotarska B.
    Acta Biochim Pol; 2002; 49(2):407-20. PubMed ID: 12362982
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  • 25. Syntheses and thymidylate synthase inhibitory activity of the poly-gamma-glutamyl conjugates of N-[5-[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino ]-2-thenoyl]-L-glutamic acid (ICI D1694) and other quinazoline antifolates.
    Bisset GM, Pawelczak K, Jackman AL, Calvert AH, Hughes LR.
    J Med Chem; 1992 Mar 06; 35(5):859-66. PubMed ID: 1372358
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  • 27. Thymidylate synthase inhibitors: the in vitro activity of a series of heterocyclic benzoyl ring modified 2-desamino-2-methyl-N10-substituted-5,8-dideazafolates.
    Jackman AL, Marsham PR, Moran RG, Kimbell R, O'Connor BM, Hughes LR, Calvert AH.
    Adv Enzyme Regul; 1991 Mar 06; 31():13-27. PubMed ID: 1877386
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  • 28. Quinazoline antifolates thymidylate synthase inhibitors: lipophilic analogues with modification to the C2-methyl substituent.
    Hennequin LF, Boyle FT, Wardleworth JM, Marsham PR, Kimbell R, Jackman AL.
    J Med Chem; 1996 Feb 02; 39(3):695-704. PubMed ID: 8576912
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  • 29. Quinazoline antifolates inhibiting thymidylate synthase: 4-thio-substituted analogues.
    Thornton TJ, Jones TR, Jackman AL, Flinn A, O'Connor BM, Warner P, Calvert AH.
    J Med Chem; 1991 Mar 02; 34(3):978-84. PubMed ID: 2002476
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  • 30. Quinazoline antifolates inhibiting thymidylate synthase: computer modelling of the N10 substituent.
    Jones TR, Betteridge RF, Neidle S, Jackman AL, Calvert AH.
    Anticancer Drug Des; 1989 Mar 02; 3(4):243-8. PubMed ID: 2930626
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  • 31. Quinazoline antifolate thymidylate synthase inhibitors: difluoro-substituted benzene ring analogues.
    Thornton TJ, Jackman AL, Marsham PR, O'Connor BM, Bishop JA, Calvert AH.
    J Med Chem; 1992 Jun 12; 35(12):2321-7. PubMed ID: 1613755
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  • 32. Mechanism-based inhibition of human folylpolyglutamate synthetase: design, synthesis, and biochemical characterization of a phosphapeptide mimic of the tetrahedral intermediate.
    Tsukamoto T, Haile WH, McGuire JJ, Coward JK.
    Arch Biochem Biophys; 1998 Jul 01; 355(1):109-18. PubMed ID: 9647673
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  • 33. Synthesis and biological activity of N(alpha)-[4-[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-N-propargylamino]phenylacetyl]-L-glutamic acid.
    Kusakiewicz-Dawid A, Bugaj M, Dzik JM, Gołos B, Wińska P, Pawełczak K, Rzeszotarska B, Rode W.
    Acta Biochim Pol; 2002 Jul 01; 49(1):197-203. PubMed ID: 12136941
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  • 34. Folate analogues. 30. Synthesis and biological evaluation of N10-propargyl-5,8-dideaza-5,6,7,8-tetrahydrofolic acid and related compounds.
    Nair MG, Dhawan R, Ghazala M, Kalman TI, Ferone R, Gaumont Y, Kisliuk RL.
    J Med Chem; 1987 Jul 01; 30(7):1256-61. PubMed ID: 3599032
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  • 37. Quinazoline antifolate thymidylate synthase inhibitors: replacement of glutamic acid in the C2-methyl series.
    Marsham PR, Jackman AL, Barker AJ, Boyle FT, Pegg SJ, Wardleworth JM, Kimbell R, O'Connor BM, Calvert AH, Hughes LR.
    J Med Chem; 1995 Mar 17; 38(6):994-1004. PubMed ID: 7699716
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  • 38. Quinazoline antifolates inhibiting thymidylate synthase: benzoyl ring modifications.
    Jones TR, Smithers MJ, Taylor MA, Jackman AL, Calvert AH, Harland SJ, Harrap KR.
    J Med Chem; 1986 Apr 17; 29(4):468-72. PubMed ID: 3754284
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  • 39. Quinazoline antifolate thymidylate synthase inhibitors: alkyl, substituted alkyl, and aryl substituents in the C2 position.
    Hughes LR, Jackman AL, Oldfield J, Smith RC, Burrows KD, Marsham PR, Bishop JA, Jones TR, O'Connor BM, Calvert AH.
    J Med Chem; 1990 Nov 17; 33(11):3060-7. PubMed ID: 2231606
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  • 40. Synthesis and antifolate evaluation of the 10-propargyl derivatives of 5-deazafolic acid, 5-deazaaminopterin, and 5-methyl-5-deazaaminopterin.
    Piper JR, Malik ND, Rhee MS, Galivan J, Sirotnak FM.
    J Med Chem; 1992 Jan 24; 35(2):332-7. PubMed ID: 1732551
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