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Journal Abstract Search

257 related items for PubMed ID: 9168257

  • 1. Hydrogen peroxide supports human and rat cytochrome P450 1A2-catalyzed 2-amino-3-methylimidazo[4,5-f]quinoline bioactivation to mutagenic metabolites: significance of cytochrome P450 peroxygenase.
    Anari MR, Josephy PD, Henry T, O'Brien PJ.
    Chem Res Toxicol; 1997 May; 10(5):582-8. PubMed ID: 9168257
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  • 2. Cytochrome P450 dependent xenobiotic activation by physiological hydroperoxides in intact hepatocytes.
    Anari MR, Khan S, Jatoe SD, O'Brien PJ.
    Eur J Drug Metab Pharmacokinet; 1997 May; 22(4):305-10. PubMed ID: 9512925
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  • 3. Cytochromes P450 in cynomolgus monkeys mutagenically activate 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) but not 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
    Sadrieh N, Snyderwine EG.
    Carcinogenesis; 1995 Jul; 16(7):1549-55. PubMed ID: 7614688
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  • 4. The inhibition by flavonoids of 2-amino-3-methylimidazo[4,5-f]quinoline metabolic activation to a mutagen: a structure-activity relationship study.
    Edenharder R, Rauscher R, Platt KL.
    Mutat Res; 1997 Sep 05; 379(1):21-32. PubMed ID: 9330619
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  • 9. Evaluation of Escherichia coli DJ4309 expressing human P450 1A2 in mutagenicity testing of complex food mixtures.
    Constable A, Varga N, Josephy PD, Guy P, Turesky RJ.
    Mutat Res; 1999 Jun 25; 442(2):79-87. PubMed ID: 10393276
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  • 10. Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes.
    Yamazaki H, Mimura M, Oda Y, Inui Y, Shiraga T, Iwasaki K, Guengerich FP, Shimada T.
    Carcinogenesis; 1993 Jul 25; 14(7):1271-8. PubMed ID: 8330339
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  • 13. Cytochrome P450 forms in the rodent lung involved in the metabolic activation of food-derived heterocyclic amines.
    Hellmold H, Overvik E, Strömstedt M, Gustafsson JA.
    Carcinogenesis; 1993 Sep 25; 14(9):1751-7. PubMed ID: 8403195
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  • 14. Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human.
    Edwards RJ, Murray BP, Murray S, Schulz T, Neubert D, Gant TW, Thorgeirsson SS, Boobis AR, Davies DS.
    Carcinogenesis; 1994 May 25; 15(5):829-36. PubMed ID: 8200083
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  • 15. Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.
    Turesky RJ, Constable A, Richoz J, Varga N, Markovic J, Martin MV, Guengerich FP.
    Chem Res Toxicol; 1998 Aug 25; 11(8):925-36. PubMed ID: 9705755
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  • 16. Identification of new 2-amino-3-methylimidazo[4,5-f]quinoline urinary metabolites from beta-naphthoflavone-treated mice.
    Lakshmi VM, Hsu FF, Zenser TV.
    Drug Metab Dispos; 2009 Aug 25; 37(8):1690-7. PubMed ID: 19451400
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  • 17. Mutagenic activation of IQ, PhIP and MeIQx by hepatic microsomes from rat, monkey and man: low mutagenic activation of MeIQx in cynomolgus monkeys in vitro reflects low DNA adduct levels in vivo.
    Davis CD, Schut HA, Adamson RH, Thorgeirsson UP, Thorgeirsson SS, Snyderwine EG.
    Carcinogenesis; 1993 Jan 25; 14(1):61-5. PubMed ID: 8425272
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  • 18. Activation and effects of the food-derived heterocyclic amines in extrahepatic tissues.
    Overvik E, Hellmold H, Branting C, Gustafsson JA.
    Princess Takamatsu Symp; 1995 Jan 25; 23():123-33. PubMed ID: 8844803
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  • 19. Selection of human cytochrome P450 1A2 mutants with enhanced catalytic activity for heterocyclic amine N-hydroxylation.
    Kim D, Guengerich FP.
    Biochemistry; 2004 Feb 03; 43(4):981-8. PubMed ID: 14744142
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  • 20. Regioselective differences in C(8)- and N-oxidation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by human and rat liver microsomes and cytochromes P450 1A2.
    Turesky RJ, Parisod V, Huynh-Ba T, Langouët S, Guengerich FP.
    Chem Res Toxicol; 2001 Jul 03; 14(7):901-11. PubMed ID: 11453738
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