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PUBMED FOR HANDHELDS

Journal Abstract Search


1085 related items for PubMed ID: 9171884

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  • 2. Three-dimensional molecular models of the hMC1R melanocortin receptor: complexes with melanotropin peptide agonists.
    Haskell-Luevano C, Sawyer TK, Trumpp-Kallmeyer S, Bikker JA, Humblet C, Gantz I, Hruby VJ.
    Drug Des Discov; 1996 Dec; 14(3):197-211. PubMed ID: 9017363
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  • 8. Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors.
    Hruby VJ, Lu D, Sharma SD, Castrucci AL, Kesterson RA, al-Obeidi FA, Hadley ME, Cone RD.
    J Med Chem; 1995 Sep 01; 38(18):3454-61. PubMed ID: 7658432
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  • 9. Characterizations of the unusual dissociation properties of melanotropin peptides from the melanocortin receptor, hMC1R.
    Haskell-Luevano C, Miwa H, Dickinson C, Hadley ME, Hruby VJ, Yamada T, Gantz I.
    J Med Chem; 1996 Jan 19; 39(2):432-5. PubMed ID: 8558511
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  • 10. Potent and selective agonists of human melanocortin receptor 5: cyclic analogues of alpha-melanocyte-stimulating hormone.
    Bednarek MA, MacNeil T, Tang R, Fong TM, Cabello MA, Maroto M, Teran A.
    J Med Chem; 2007 May 17; 50(10):2520-6. PubMed ID: 17455928
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  • 12. De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach.
    Han G, Haskell-Luevano C, Kendall L, Bonner G, Hadley ME, Cone RD, Hruby VJ.
    J Med Chem; 2004 Mar 11; 47(6):1514-26. PubMed ID: 14998337
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  • 14. Structure-activity relationships of the unique and potent agouti-related protein (AGRP)-melanocortin chimeric Tyr-c[beta-Asp-His-DPhe-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH2 peptide template.
    Wilczynski A, Wilson KR, Scott JW, Edison AS, Haskell-Luevano C.
    J Med Chem; 2005 Apr 21; 48(8):3060-75. PubMed ID: 15828845
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  • 15. Chimeric NDP-MSH and MTII melanocortin peptides with agouti-related protein (AGRP) Arg-Phe-Phe amino acids possess agonist melanocortin receptor activity.
    Joseph CG, Wilczynski A, Holder JR, Xiang Z, Bauzo RM, Scott JW, Haskell-Luevano C.
    Peptides; 2003 Dec 21; 24(12):1899-908. PubMed ID: 15127941
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  • 16. Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics.
    Al-Obeidi F, Castrucci AM, Hadley ME, Hruby VJ.
    J Med Chem; 1989 Dec 21; 32(12):2555-61. PubMed ID: 2555512
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  • 18. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist.
    Frändberg PA, Doufexis M, Kapas S, Chhajlani V.
    Biochem Biophys Res Commun; 2001 Mar 09; 281(4):851-7. PubMed ID: 11237737
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  • 20. Biological and conformational study of beta-substituted prolines in MT-II template: steric effects leading to human MC5 receptor selectivity.
    Cai M, Cai C, Mayorov AV, Xiong C, Cabello CM, Soloshonok VA, Swift JR, Trivedi D, Hruby VJ.
    J Pept Res; 2004 Feb 09; 63(2):116-31. PubMed ID: 15009533
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