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403 related items for PubMed ID: 9174667

  • 1. Accumulation of sphingolipids in SAP-precursor (prosaposin)-deficient fibroblasts occurs as intralysosomal membrane structures and can be completely reversed by treatment with human SAP-precursor.
    Burkhardt JK, Hüttler S, Klein A, Möbius W, Habermann A, Griffiths G, Sandhoff K.
    Eur J Cell Biol; 1997 May; 73(1):10-8. PubMed ID: 9174667
    [Abstract] [Full Text] [Related]

  • 2. Processing of sphingolipid activator proteins and the topology of lysosomal digestion.
    Sandhoff K, Kolter T.
    Acta Biochim Pol; 1998 May; 45(2):373-84. PubMed ID: 9821868
    [Abstract] [Full Text] [Related]

  • 3. Saposin B mobilizes lipids from cholesterol-poor and bis(monoacylglycero)phosphate-rich membranes at acidic pH. Unglycosylated patient variant saposin B lacks lipid-extraction capacity.
    Remmel N, Locatelli-Hoops S, Breiden B, Schwarzmann G, Sandhoff K.
    FEBS J; 2007 Jul; 274(13):3405-20. PubMed ID: 17561962
    [Abstract] [Full Text] [Related]

  • 4. Degradation of membrane-bound ganglioside GM1. Stimulation by bis(monoacylglycero)phosphate and the activator proteins SAP-B and GM2-AP.
    Wilkening G, Linke T, Uhlhorn-Dierks G, Sandhoff K.
    J Biol Chem; 2000 Nov 17; 275(46):35814-9. PubMed ID: 10942779
    [Abstract] [Full Text] [Related]

  • 5. Sphingolipid activator protein D (sap-D) stimulates the lysosomal degradation of ceramide in vivo.
    Klein A, Henseler M, Klein C, Suzuki K, Harzer K, Sandhoff K.
    Biochem Biophys Res Commun; 1994 May 16; 200(3):1440-8. PubMed ID: 8185598
    [Abstract] [Full Text] [Related]

  • 6. Saposin C-LBPA interaction in late-endosomes/lysosomes.
    Chu Z, Witte DP, Qi X.
    Exp Cell Res; 2005 Feb 15; 303(2):300-7. PubMed ID: 15652344
    [Abstract] [Full Text] [Related]

  • 7. Biogenesis of lysosomes in marshall cells and in cells of the male reproductive system.
    Morales CR, Fuska J, Zhao Q, Lefrancois S.
    Mol Reprod Dev; 2001 May 15; 59(1):54-66. PubMed ID: 11335947
    [Abstract] [Full Text] [Related]

  • 8. Physiological relevance of sphingolipid activator proteins in cultured human fibroblasts.
    Sadeghlar F, Remmel N, Breiden B, Klingenstein R, Schwarzmann G, Sandhoff K.
    Biochimie; 2003 May 15; 85(3-4):439-48. PubMed ID: 12770782
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  • 10. Immunocytochemical localization of sphingolipid activator protein 2 (SAP-2) in normal and SAP-deficient fibroblasts.
    Paton BC, Hughes JL, Harzer K, Poulos A.
    Eur J Cell Biol; 1990 Feb 15; 51(1):157-64. PubMed ID: 2109697
    [Abstract] [Full Text] [Related]

  • 11. Intracellular trafficking of glycosphingolipids: role of sphingolipid activator proteins in the topology of endocytosis and lysosomal digestion.
    Sandhoff K, Klein A.
    FEBS Lett; 1994 Jun 06; 346(1):103-7. PubMed ID: 8206147
    [Abstract] [Full Text] [Related]

  • 12. Sphingolipid activator proteins (SAPs) are stored together with glycosphingolipids in the infantile neuronal ceroid-lipofuscinosis (INCL).
    Tyynelä J, Baumann M, Henseler M, Sandhoff K, Haltia M.
    Am J Med Genet; 1995 Jun 05; 57(2):294-7. PubMed ID: 7668348
    [Abstract] [Full Text] [Related]

  • 13. Prosaposin deficiency: further characterization of the sphingolipid activator protein-deficient sibs. Multiple glycolipid elevations (including lactosylceramidosis), partial enzyme deficiencies and ultrastructure of the skin in this generalized sphingolipid storage disease.
    Bradová V, Smíd F, Ulrich-Bott B, Roggendorf W, Paton BC, Harzer K.
    Hum Genet; 1993 Sep 05; 92(2):143-52. PubMed ID: 8370580
    [Abstract] [Full Text] [Related]

  • 14. Saposin C is required for lipid presentation by human CD1b.
    Winau F, Schwierzeck V, Hurwitz R, Remmel N, Sieling PA, Modlin RL, Porcelli SA, Brinkmann V, Sugita M, Sandhoff K, Kaufmann SH, Schaible UE.
    Nat Immunol; 2004 Feb 05; 5(2):169-74. PubMed ID: 14716313
    [Abstract] [Full Text] [Related]

  • 15. Biosynthesis, processing, and targeting of sphingolipid activator protein (SAP )precursor in cultured human fibroblasts. Mannose 6-phosphate receptor-independent endocytosis of SAP precursor.
    Vielhaber G, Hurwitz R, Sandhoff K.
    J Biol Chem; 1996 Dec 13; 271(50):32438-46. PubMed ID: 8943309
    [Abstract] [Full Text] [Related]

  • 16. Expression of the three alternative forms of the sphingolipid activator protein precursor in baby hamster kidney cells and functional assays in a cell culture system.
    Henseler M, Klein A, Glombitza GJ, Suziki K, Sandhoff K.
    J Biol Chem; 1996 Apr 05; 271(14):8416-23. PubMed ID: 8626540
    [Abstract] [Full Text] [Related]

  • 17. Principles of lysosomal membrane digestion: stimulation of sphingolipid degradation by sphingolipid activator proteins and anionic lysosomal lipids.
    Kolter T, Sandhoff K.
    Annu Rev Cell Dev Biol; 2005 Apr 05; 21():81-103. PubMed ID: 16212488
    [Abstract] [Full Text] [Related]

  • 18. Sphingolipids and lysosomal pathologies.
    Schulze H, Sandhoff K.
    Biochim Biophys Acta; 2014 May 05; 1841(5):799-810. PubMed ID: 24184515
    [Abstract] [Full Text] [Related]

  • 19. The inactivation of the sortilin gene leads to a partial disruption of prosaposin trafficking to the lysosomes.
    Zeng J, Racicott J, Morales CR.
    Exp Cell Res; 2009 Nov 01; 315(18):3112-24. PubMed ID: 19732768
    [Abstract] [Full Text] [Related]

  • 20. The lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilin.
    Lefrancois S, Zeng J, Hassan AJ, Canuel M, Morales CR.
    EMBO J; 2003 Dec 15; 22(24):6430-7. PubMed ID: 14657016
    [Abstract] [Full Text] [Related]

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