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101 related items for PubMed ID: 9185604

  • 1. Phosphorylation of both phosphoacceptor sites in the HIV-1 Vpu cytoplasmic domain is essential for Vpu-mediated ER degradation of CD4.
    Paul M, Jabbar MA.
    Virology; 1997 May 26; 232(1):207-16. PubMed ID: 9185604
    [Abstract] [Full Text] [Related]

  • 2. The human immunodeficiency virus type 1 Vpu protein tethered to the CD4 extracellular domain is localized to the plasma membrane and is biologically active in the secretory pathway of mammalian cells: implications for the mechanisms of Vpu function.
    Raja NU, Jabbar MA.
    Virology; 1996 Jun 01; 220(1):141-51. PubMed ID: 8659106
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  • 4. Degradation of CD4 induced by human immunodeficiency virus type 1 Vpu protein: a predicted alpha-helix structure in the proximal cytoplasmic region of CD4 contributes to Vpu sensitivity.
    Yao XJ, Friborg J, Checroune F, Gratton S, Boisvert F, Sékaly RP, Cohen EA.
    Virology; 1995 Jun 01; 209(2):615-23. PubMed ID: 7778293
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  • 5. Structural and functional analysis of the membrane-spanning domain of the human immunodeficiency virus type 1 Vpu protein.
    Tiganos E, Friborg J, Allain B, Daniel NG, Yao XJ, Cohen EA.
    Virology; 1998 Nov 10; 251(1):96-107. PubMed ID: 9813206
    [Abstract] [Full Text] [Related]

  • 6. Interaction between the cytoplasmic domains of HIV-1 Vpu and CD4: role of Vpu residues involved in CD4 interaction and in vitro CD4 degradation.
    Margottin F, Benichou S, Durand H, Richard V, Liu LX, Gomas E, Benarous R.
    Virology; 1996 Sep 15; 223(2):381-6. PubMed ID: 8806575
    [Abstract] [Full Text] [Related]

  • 7. Vpu-mediated CD4 down-regulation and degradation is conserved among highly divergent SIV(cpz) strains.
    Gomez LM, Pacyniak E, Flick M, Hout DR, Gomez ML, Nerrienet E, Ayouba A, Santiago ML, Hahn BH, Stephens EB.
    Virology; 2005 Apr 25; 335(1):46-60. PubMed ID: 15823605
    [Abstract] [Full Text] [Related]

  • 8. Stimulation of heterologous protein degradation by the Vpu protein of HIV-1 requires the transmembrane and cytoplasmic domains of CD4.
    Buonocore L, Turi TG, Crise B, Rose JK.
    Virology; 1994 Oct 25; 204(1):482-6. PubMed ID: 8091684
    [Abstract] [Full Text] [Related]

  • 9. NMR studies of the phosphorylation motif of the HIV-1 protein Vpu bound to the F-box protein beta-TrCP.
    Coadou G, Gharbi-Benarous J, Megy S, Bertho G, Evrard-Todeschi N, Segeral E, Benarous R, Girault JP.
    Biochemistry; 2003 Dec 23; 42(50):14741-51. PubMed ID: 14674748
    [Abstract] [Full Text] [Related]

  • 10. Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHIVKU1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques.
    Hout DR, Gomez ML, Pacyniak E, Gomez LM, Fegley B, Mulcahy ER, Hill MS, Culley N, Pinson DM, Nothnick W, Powers MF, Wong SW, Stephens EB.
    Virology; 2006 Jan 20; 344(2):541-59. PubMed ID: 16199074
    [Abstract] [Full Text] [Related]

  • 11. A single amino acid substitution within the transmembrane domain of the human immunodeficiency virus type 1 Vpu protein renders simian-human immunodeficiency virus (SHIV(KU-1bMC33)) susceptible to rimantadine.
    Hout DR, Gomez LM, Pacyniak E, Miller JM, Hill MS, Stephens EB.
    Virology; 2006 May 10; 348(2):449-61. PubMed ID: 16458946
    [Abstract] [Full Text] [Related]

  • 12. Human immunodeficiency virus type 1 Vpu protein induces degradation of chimeric envelope glycoproteins bearing the cytoplasmic and anchor domains of CD4: role of the cytoplasmic domain in Vpu-induced degradation in the endoplasmic reticulum.
    Vincent MJ, Raja NU, Jabbar MA.
    J Virol; 1993 Sep 10; 67(9):5538-49. PubMed ID: 8350411
    [Abstract] [Full Text] [Related]

  • 13. Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles.
    Estrabaud E, Le Rouzic E, Lopez-Vergès S, Morel M, Belaïdouni N, Benarous R, Transy C, Berlioz-Torrent C, Margottin-Goguet F.
    PLoS Pathog; 2007 Jul 27; 3(7):e104. PubMed ID: 17676996
    [Abstract] [Full Text] [Related]

  • 14. The human immunodeficiency virus type 1 Vpu protein: a potential regulator of proteolysis and protein transport in the mammalian secretory pathway.
    Vincent MJ, Abdul Jabbar M.
    Virology; 1995 Nov 10; 213(2):639-49. PubMed ID: 7491787
    [Abstract] [Full Text] [Related]

  • 15. Structural consequences of phosphorylation of two serine residues in the cytoplasmic domain of HIV-1 VpU.
    Wittlich M, Koenig BW, Willbold D.
    J Pept Sci; 2008 Jul 10; 14(7):804-10. PubMed ID: 18186541
    [Abstract] [Full Text] [Related]

  • 16. Putative alpha-helical structures in the human immunodeficiency virus type 1 Vpu protein and CD4 are involved in binding and degradation of the CD4 molecule.
    Tiganos E, Yao XJ, Friborg J, Daniel N, Cohen EA.
    J Virol; 1997 Jun 10; 71(6):4452-60. PubMed ID: 9151836
    [Abstract] [Full Text] [Related]

  • 17. Functional analysis of the phosphorylation sites on the human immunodeficiency virus type 1 Vpu protein.
    Friborg J, Ladha A, Göttlinger H, Haseltine WA, Cohen EA.
    J Acquir Immune Defic Syndr Hum Retrovirol; 1995 Jan 01; 8(1):10-22. PubMed ID: 8548340
    [Abstract] [Full Text] [Related]

  • 18. Epitope mapping of the phosphorylation motif of the HIV-1 protein Vpu bound to the selective monoclonal antibody using TRNOESY and STD NMR spectroscopy.
    Gharbi-Benarous J, Bertho G, Evrard-Todeschi N, Coadou G, Megy S, Delaunay T, Benarous R, Girault JP.
    Biochemistry; 2004 Nov 23; 43(46):14555-65. PubMed ID: 15544326
    [Abstract] [Full Text] [Related]

  • 19. The human immunodeficiency virus type 1 Vpu protein specifically binds to the cytoplasmic domain of CD4: implications for the mechanism of degradation.
    Bour S, Schubert U, Strebel K.
    J Virol; 1995 Mar 23; 69(3):1510-20. PubMed ID: 7853484
    [Abstract] [Full Text] [Related]

  • 20. Vpu-mediated proteolysis of gp160/CD4 chimeric envelope glycoproteins in the endoplasmic reticulum: requirement of both the anchor and cytoplasmic domains of CD4.
    Raja NU, Vincent MJ, abdul Jabbar M.
    Virology; 1994 Oct 23; 204(1):357-66. PubMed ID: 8091666
    [Abstract] [Full Text] [Related]

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