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Journal Abstract Search

115 related items for PubMed ID: 9190897

  • 1. Geldanamycin-stimulated destabilization of mutated p53 is mediated by the proteasome in vivo.
    Whitesell L, Sutphin P, An WG, Schulte T, Blagosklonny MV, Neckers L.
    Oncogene; 1997 Jun 12; 14(23):2809-16. PubMed ID: 9190897
    [Abstract] [Full Text] [Related]

  • 2. The stabilization mechanism of mutant-type p53 by impaired ubiquitination: the loss of wild-type p53 function and the hsp90 association.
    Nagata Y, Anan T, Yoshida T, Mizukami T, Taya Y, Fujiwara T, Kato H, Saya H, Nakao M.
    Oncogene; 1999 Oct 28; 18(44):6037-49. PubMed ID: 10557093
    [Abstract] [Full Text] [Related]

  • 3. Inhibitors of transcription, proteasome inhibitors, and DNA-damaging drugs differentially affect feedback of p53 degradation.
    An WG, Chuman Y, Fojo T, Blagosklonny MV.
    Exp Cell Res; 1998 Oct 10; 244(1):54-60. PubMed ID: 9770348
    [Abstract] [Full Text] [Related]

  • 4. Geldanamycin-induced destabilization of Raf-1 involves the proteasome.
    Schulte TW, An WG, Neckers LM.
    Biochem Biophys Res Commun; 1997 Oct 29; 239(3):655-9. PubMed ID: 9367823
    [Abstract] [Full Text] [Related]

  • 5. Proteasome-dependent regulation of p21WAF1/CIP1 expression.
    Blagosklonny MV, Wu GS, Omura S, el-Deiry WS.
    Biochem Biophys Res Commun; 1996 Oct 14; 227(2):564-9. PubMed ID: 8878553
    [Abstract] [Full Text] [Related]

  • 6. CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90.
    Goasduff T, Cederbaum AI.
    Arch Biochem Biophys; 2000 Jul 15; 379(2):321-30. PubMed ID: 10898951
    [Abstract] [Full Text] [Related]

  • 7. Geldanamycin abrogates ErbB2 association with proteasome-resistant beta-catenin in melanoma cells, increases beta-catenin-E-cadherin association, and decreases beta-catenin-sensitive transcription.
    Bonvini P, An WG, Rosolen A, Nguyen P, Trepel J, Garcia de Herreros A, Dunach M, Neckers LM.
    Cancer Res; 2001 Feb 15; 61(4):1671-7. PubMed ID: 11245482
    [Abstract] [Full Text] [Related]

  • 8. Accelerated degradation of cellular FLIP protein through the ubiquitin-proteasome pathway in p53-mediated apoptosis of human cancer cells.
    Fukazawa T, Fujiwara T, Uno F, Teraishi F, Kadowaki Y, Itoshima T, Takata Y, Kagawa S, Roth JA, Tschopp J, Tanaka N.
    Oncogene; 2001 Aug 23; 20(37):5225-31. PubMed ID: 11526513
    [Abstract] [Full Text] [Related]

  • 9. Rapid deubiquitination of nucleosomal histones in human tumor cells caused by proteasome inhibitors and stress response inducers: effects on replication, transcription, translation, and the cellular stress response.
    Mimnaugh EG, Chen HY, Davie JR, Celis JE, Neckers L.
    Biochemistry; 1997 Nov 25; 36(47):14418-29. PubMed ID: 9398160
    [Abstract] [Full Text] [Related]

  • 10. Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin.
    Mimnaugh EG, Chavany C, Neckers L.
    J Biol Chem; 1996 Sep 13; 271(37):22796-801. PubMed ID: 8798456
    [Abstract] [Full Text] [Related]

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  • 14. The physical association of multiple molecular chaperone proteins with mutant p53 is altered by geldanamycin, an hsp90-binding agent.
    Whitesell L, Sutphin PD, Pulcini EJ, Martinez JD, Cook PH.
    Mol Cell Biol; 1998 Mar 13; 18(3):1517-24. PubMed ID: 9488468
    [Abstract] [Full Text] [Related]

  • 15. Geldanamycin selectively destabilizes and conformationally alters mutated p53.
    Blagosklonny MV, Toretsky J, Neckers L.
    Oncogene; 1995 Sep 07; 11(5):933-9. PubMed ID: 7675452
    [Abstract] [Full Text] [Related]

  • 16. Geldanamycin and its analogue 17-allylamino-17-demethoxygeldanamycin lowers Bcr-Abl levels and induces apoptosis and differentiation of Bcr-Abl-positive human leukemic blasts.
    Nimmanapalli R, O'Bryan E, Bhalla K.
    Cancer Res; 2001 Mar 01; 61(5):1799-804. PubMed ID: 11280726
    [Abstract] [Full Text] [Related]

  • 17. [Ligand-induced polyubiquitination of receptor tyrosine kinases].
    Mori S.
    Tanpakushitsu Kakusan Koso; 1997 Oct 01; 42(14 Suppl):2284-90. PubMed ID: 9366209
    [No Abstract] [Full Text] [Related]

  • 18. Geldanamycin prevents nuclear translocation of mutant p53.
    Dasgupta G, Momand J.
    Exp Cell Res; 1997 Nov 25; 237(1):29-37. PubMed ID: 9417863
    [Abstract] [Full Text] [Related]

  • 19. The benzoquinone ansamycin geldanamycin stimulates proteolytic degradation of focal adhesion kinase.
    Ochel HJ, Schulte TW, Nguyen P, Trepel J, Neckers L.
    Mol Genet Metab; 1999 Jan 25; 66(1):24-30. PubMed ID: 9973544
    [Abstract] [Full Text] [Related]

  • 20. Proteasome inhibitors induce p53/p21-independent apoptosis in human glioma cells.
    Wagenknecht B, Hermisson M, Eitel K, Weller M.
    Cell Physiol Biochem; 1999 Jan 25; 9(3):117-25. PubMed ID: 10494025
    [Abstract] [Full Text] [Related]

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