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Journal Abstract Search

153 related items for PubMed ID: 9195221

  • 1. Phase I study of direct administration of a replication deficient adenovirus vector containing the E. coli cytosine deaminase gene to metastatic colon carcinoma of the liver in association with the oral administration of the pro-drug 5-fluorocytosine.
    Crystal RG, Hirschowitz E, Lieberman M, Daly J, Kazam E, Henschke C, Yankelevitz D, Kemeny N, Silverstein R, Ohwada A, Russi T, Mastrangeli A, Sanders A, Cooke J, Harvey BG.
    Hum Gene Ther; 1997 May 20; 8(8):985-1001. PubMed ID: 9195221
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  • 2. Regional 'pro-drug' gene therapy: intravenous administration of an adenoviral vector expressing the E. coli cytosine deaminase gene and systemic administration of 5-fluorocytosine suppresses growth of hepatic metastasis of colon carcinoma.
    Topf N, Worgall S, Hackett NR, Crystal RG.
    Gene Ther; 1998 Apr 20; 5(4):507-13. PubMed ID: 9614575
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  • 3. Enzyme/prodrug gene therapy for human colon cancer cells using adenovirus-mediated transfer of the Escherichia coli cytosine deaminase gene driven by a CAG promoter associated with 5-fluorocytosine administration.
    Koyama F, Sawada H, Fujii H, Hirao T, Ueno M, Hamada H, Nakano H.
    J Exp Clin Cancer Res; 2000 Mar 20; 19(1):75-80. PubMed ID: 10840940
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  • 4. Adenovirus-mediated GM-CSF gene and cytosine deaminase gene transfer followed by 5-fluorocytosine administration elicit more potent antitumor response in tumor-bearing mice.
    Cao X, Ju DW, Tao Q, Wang J, Wan T, Wang BM, Zhang W, Hamada H.
    Gene Ther; 1998 Aug 20; 5(8):1130-6. PubMed ID: 10326037
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  • 7. Cytosine deaminase/5-fluorocytosine-based vaccination against liver tumors: evidence of distant bystander effect.
    Pierrefite-Carle V, Baqué P, Gavelli A, Mala M, Chazal M, Gugenheim J, Bourgeon A, Milano G, Staccini P, Rossi B.
    J Natl Cancer Inst; 1999 Dec 01; 91(23):2014-9. PubMed ID: 10580026
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  • 10. Combined suicide gene therapy for human colon cancer cells using adenovirus-mediated transfer of escherichia coli cytosine deaminase gene and Escherichia coli uracil phosphoribosyltransferase gene with 5-fluorocytosine.
    Koyama F, Sawada H, Hirao T, Fujii H, Hamada H, Nakano H.
    Cancer Gene Ther; 2000 Jul 01; 7(7):1015-22. PubMed ID: 10917204
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  • 15. Hepatic intra-arterial delivery of a retroviral vector expressing the cytosine deaminase gene, controlled by the CEA promoter and intraperitoneal treatment with 5-fluorocytosine suppresses growth of colorectal liver metastases.
    Humphreys MJ, Ghaneh P, Greenhalf W, Campbell F, Clayton TM, Everett P, Huber BE, Richards CA, Ford MJ, Neoptolemos JP.
    Gene Ther; 2001 Aug 01; 8(16):1241-7. PubMed ID: 11509957
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  • 19. Systemic interleukin-6 responses following administration of adenovirus gene transfer vectors to humans by different routes.
    Ben-Gary H, McKinney RL, Rosengart T, Lesser ML, Crystal RG.
    Mol Ther; 2002 Aug 01; 6(2):287-97. PubMed ID: 12349828
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