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Journal Abstract Search

140 related items for PubMed ID: 9209689

  • 1. Implication of CYP 3A in the toxicity of cyclosporin G (CsG), cyclosporin A (CsA) and FK506 on rat hepatocytes in primary culture.
    Ellouk-Achard S, Martin C, Pham-Huy C, Duc HT, Thevenin M, Dutertre-Catella H, Warnet JM, Claude JR.
    Arch Toxicol; 1997; 71(7):437-42. PubMed ID: 9209689
    [Abstract] [Full Text] [Related]

  • 2. FK506 (Tacrolimus) decreases the cytotoxicity of cyclosporin A in rat hepatocytes in primary culture: implication of CYP3A induction.
    Ellouk-Achard S, Martin C, Duc HT, Dutertre-Catella H, Thevenin M, Warnet JM, Claude JR.
    Arch Toxicol; 1998 Apr; 72(5):257-63. PubMed ID: 9630010
    [Abstract] [Full Text] [Related]

  • 3. Modulation of energy status and cytotoxicity induced by FK506 and cyclosporin A in a renal epithelial cell line.
    Massicot F, Martin C, Dutertre-Catella H, Ellouk-Achard S, Pham-Huy C, Thevenin M, Rucay P, Warnet JM, Claude JR.
    Arch Toxicol; 1997 Apr; 71(8):529-31. PubMed ID: 9248632
    [Abstract] [Full Text] [Related]

  • 4. Experimental nephrotoxicity, hepatotoxicity and pharmacokinetics of cyclosporin G versus cyclosporin A.
    Burdmann EA, Andoh TF, Rosen S, Lindsley J, Munar MY, Elzinga LW, Bennett WM.
    Kidney Int; 1994 Mar; 45(3):684-91. PubMed ID: 8196271
    [Abstract] [Full Text] [Related]

  • 5. Cyclosporine A and FK506 induce osteoclast apoptosis in mouse bone marrow cell cultures.
    Igarashi K, Hirotani H, Woo JT, Stern PH.
    Bone; 2004 Jul; 35(1):47-56. PubMed ID: 15207740
    [Abstract] [Full Text] [Related]

  • 6. In vivo effects of cyclosporin A and ketoconazole on the pharmacokinetics of representative substrates for P-glycoprotein and cytochrome P450 (CYP) 3A in rats.
    Kageyama M, Namiki H, Fukushima H, Ito Y, Shibata N, Takada K.
    Biol Pharm Bull; 2005 Feb; 28(2):316-22. PubMed ID: 15684491
    [Abstract] [Full Text] [Related]

  • 7. Use of human organ slices to evaluate the biotransformation and drug-induced side-effects of pharmaceuticals.
    Vickers AE.
    Cell Biol Toxicol; 1994 Dec; 10(5-6):407-14. PubMed ID: 7697504
    [Abstract] [Full Text] [Related]

  • 8. Troglitazone increases cytochrome P-450 3A protein and activity in primary cultures of human hepatocytes.
    Ramachandran V, Kostrubsky VE, Komoroski BJ, Zhang S, Dorko K, Esplen JE, Strom SC, Venkataramanan R.
    Drug Metab Dispos; 1999 Oct; 27(10):1194-9. PubMed ID: 10497147
    [Abstract] [Full Text] [Related]

  • 9. Characterization of rat cytochrome P450 isozymes involved in the covalent binding of cyclosporin A to microsomal proteins.
    Sadrieh N, Thomas PE.
    Toxicol Appl Pharmacol; 1994 Aug; 127(2):222-32. PubMed ID: 8048065
    [Abstract] [Full Text] [Related]

  • 10. Primary porcine enterocyte and hepatocyte cultures to study drug oxidation reactions.
    Bader A, Hansen T, Kirchner G, Allmeling C, Haverich A, Borlak JT.
    Br J Pharmacol; 2000 Jan; 129(2):331-42. PubMed ID: 10694240
    [Abstract] [Full Text] [Related]

  • 11. Molecular and pharmacokinetic evaluation of rat hepatic and gastrointestinal cytochrome p450 induction by tamoxifen.
    Cotreau MM, von Moltke LL, Harmatz JS, Greenblatt DJ.
    Pharmacology; 2001 Jan; 63(4):210-9. PubMed ID: 11729359
    [Abstract] [Full Text] [Related]

  • 12. Cyclosporin A-induced free radical generation is not mediated by cytochrome P-450.
    Krauskopf A, Buetler TM, Nguyen NS, Macé K, Ruegg UT.
    Br J Pharmacol; 2002 Feb; 135(4):977-86. PubMed ID: 11861326
    [Abstract] [Full Text] [Related]

  • 13. Metabolism-dependent stimulation of reactive oxygen species and DNA synthesis by cyclosporin A in rat smooth muscle cells.
    Nguyen NS, Cottet-Maire F, Buetler TM, Lo Russo A, Krauskopf AS, Armstrong JM, Vickers AE, Macé K, Rüegg UT.
    Free Radic Biol Med; 1999 Dec; 27(11-12):1267-75. PubMed ID: 10641720
    [Abstract] [Full Text] [Related]

  • 14. Cyclosporine A and tacrolimus: in vitro investigations on the differential interactions with the cytochrome P450 system in rat and human liver.
    Lupp A, Kuhn UD, Herwig R, Karge E, Rost M, Scheele J, Fleck C.
    Exp Toxicol Pathol; 2003 Jun; 54(5-6):467-73. PubMed ID: 12877359
    [Abstract] [Full Text] [Related]

  • 15. Different effects of cyclosporine a and FK506 on potassium transport systems in MDCK cells.
    Aker S, Heering P, Kinne-Saffran E, Deppe C, Grabensee B, Kinne RK.
    Exp Nephrol; 2001 Jun; 9(5):332-40. PubMed ID: 11549851
    [Abstract] [Full Text] [Related]

  • 16. Comparative study of cyclosporin A, cyclosporin G, and the novel cyclosporin derivative IMM 125 in isolated glomeruli and cultured rat mesangial cells: a morphometric analysis.
    Potier M, Wolf A, Cambar J.
    Nephrol Dial Transplant; 1998 Jun; 13(6):1406-11. PubMed ID: 9641169
    [Abstract] [Full Text] [Related]

  • 17. Cytochrome P450-generated reactive metabolites cause mitochondrial permeability transition, caspase activation, and apoptosis in rat hepatocytes.
    Haouzi D, Lekéhal M, Moreau A, Moulis C, Feldmann G, Robin MA, Lettéron P, Fau D, Pessayre D.
    Hepatology; 2000 Aug; 32(2):303-11. PubMed ID: 10915737
    [Abstract] [Full Text] [Related]

  • 18. Negative regulation by dexamethasone of fluvastatin-inducible CYP2B expression in primary cultures of rat hepatocytes: role of CYP3A.
    Kocarek TA, Reddy AB.
    Biochem Pharmacol; 1998 May 01; 55(9):1435-43. PubMed ID: 10076536
    [Abstract] [Full Text] [Related]

  • 19. Effects of phenobarbital on metabolism and toxicity of diclofenac sodium in rat hepatocytes in vitro.
    Wang AG, Xia T, Yuan J, Yu RA, Yang KD, Chen XM, Qu W, Waalkes MP.
    Food Chem Toxicol; 2004 Oct 01; 42(10):1647-53. PubMed ID: 15304311
    [Abstract] [Full Text] [Related]

  • 20. In vitro investigations on the differential pro-oxidant and/or antioxidant properties of cyclosporin A and tacrolimus in human and rat liver microsomes.
    Lupp A, Kuhn UD, Karge E, Adam G, Fleck C.
    Int J Clin Pharmacol Ther; 2006 May 01; 44(5):225-32. PubMed ID: 16724577
    [Abstract] [Full Text] [Related]

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