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Journal Abstract Search

174 related items for PubMed ID: 9218872

  • 1. 7-Hydroxystaurosporine (UCN-01) causes redistribution of proliferating cell nuclear antigen and abrogates cisplatin-induced S-phase arrest in Chinese hamster ovary cells.
    Bunch RT, Eastman A.
    Cell Growth Differ; 1997 Jul; 8(7):779-88. PubMed ID: 9218872
    [Abstract] [Full Text] [Related]

  • 2. Enhancement of cisplatin-induced cytotoxicity by 7-hydroxystaurosporine (UCN-01), a new G2-checkpoint inhibitor.
    Bunch RT, Eastman A.
    Clin Cancer Res; 1996 May; 2(5):791-7. PubMed ID: 9816232
    [Abstract] [Full Text] [Related]

  • 3. UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.
    Wang Q, Fan S, Eastman A, Worland PJ, Sausville EA, O'Connor PM.
    J Natl Cancer Inst; 1996 Jul 17; 88(14):956-65. PubMed ID: 8667426
    [Abstract] [Full Text] [Related]

  • 4. Abrogation of an S-phase checkpoint and potentiation of camptothecin cytotoxicity by 7-hydroxystaurosporine (UCN-01) in human cancer cell lines, possibly influenced by p53 function.
    Shao RG, Cao CX, Shimizu T, O'Connor PM, Kohn KW, Pommier Y.
    Cancer Res; 1997 Sep 15; 57(18):4029-35. PubMed ID: 9307289
    [Abstract] [Full Text] [Related]

  • 5. [Cell cycle regulation after exposure to ionizing radiation].
    Teyssier F, Bay JO, Dionet C, Verrelle P.
    Bull Cancer; 1999 Apr 15; 86(4):345-57. PubMed ID: 10341340
    [Abstract] [Full Text] [Related]

  • 6. A novel indolocarbazole, ICP-1, abrogates DNA damage-induced cell cycle arrest and enhances cytotoxicity: similarities and differences to the cell cycle checkpoint abrogator UCN-01.
    Eastman A, Kohn EA, Brown MK, Rathman J, Livingstone M, Blank DH, Gribble GW.
    Mol Cancer Ther; 2002 Oct 15; 1(12):1067-78. PubMed ID: 12481430
    [Abstract] [Full Text] [Related]

  • 7. Comparison of the efficacy of 7-hydroxystaurosporine (UCN-01) and other staurosporine analogs to abrogate cisplatin-induced cell cycle arrest in human breast cancer cell lines.
    Lee SI, Brown MK, Eastman A.
    Biochem Pharmacol; 1999 Dec 01; 58(11):1713-21. PubMed ID: 10571245
    [Abstract] [Full Text] [Related]

  • 8. p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases.
    Medema RH, Klompmaker R, Smits VA, Rijksen G.
    Oncogene; 1998 Jan 29; 16(4):431-41. PubMed ID: 9484832
    [Abstract] [Full Text] [Related]

  • 9. 7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53.
    Shao RG, Shimizu T, Pommier Y.
    Exp Cell Res; 1997 Aug 01; 234(2):388-97. PubMed ID: 9260909
    [Abstract] [Full Text] [Related]

  • 10. UCN-01-mediated G1 arrest in normal but not tumor breast cells is pRb-dependent and p53-independent.
    Chen X, Lowe M, Keyomarsi K.
    Oncogene; 1999 Oct 07; 18(41):5691-702. PubMed ID: 10577141
    [Abstract] [Full Text] [Related]

  • 11. Requirements for p53 and the ATM gene product in the regulation of G1/S and S phase checkpoints.
    Xie G, Habbersett RC, Jia Y, Peterson SR, Lehnert BE, Bradbury EM, D'Anna JA.
    Oncogene; 1998 Feb 12; 16(6):721-36. PubMed ID: 9488036
    [Abstract] [Full Text] [Related]

  • 12. Regulation of the G2/M transition by p53.
    Taylor WR, Stark GR.
    Oncogene; 2001 Apr 05; 20(15):1803-15. PubMed ID: 11313928
    [Abstract] [Full Text] [Related]

  • 13. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
    Akiyama T, Yoshida T, Tsujita T, Shimizu M, Mizukami T, Okabe M, Akinaga S.
    Cancer Res; 1997 Apr 15; 57(8):1495-501. PubMed ID: 9108451
    [Abstract] [Full Text] [Related]

  • 14. F9 embryonal carcinoma cells fail to stop at G1/S boundary of the cell cycle after gamma-irradiation due to p21WAF1/CIP1 degradation.
    Malashicheva AB, Kislyakova TV, Aksenov ND, Osipov KA, Pospelov VA.
    Oncogene; 2000 Aug 10; 19(34):3858-65. PubMed ID: 10951579
    [Abstract] [Full Text] [Related]

  • 15. UCN-01 inhibits p53 up-regulation and abrogates gamma-radiation-induced G(2)-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1.
    Yu Q, La Rose J, Zhang H, Takemura H, Kohn KW, Pommier Y.
    Cancer Res; 2002 Oct 15; 62(20):5743-8. PubMed ID: 12384533
    [Abstract] [Full Text] [Related]

  • 16. Characterization of adriamycin-induced G2 arrest and its abrogation by caffeine in FL-amnion cells with or without p53.
    Minemoto Y, Gannon J, Masutani M, Nakagama H, Sasagawa T, Inoue M, Masamune Y, Yamashita K.
    Exp Cell Res; 2001 Jan 01; 262(1):37-48. PubMed ID: 11120603
    [Abstract] [Full Text] [Related]

  • 17. Caffeine induces S-phase apoptosis in cis-diamminedichloroplatinum-treated cells, whereas cis-diamminedichloroplatinum induces a block in G2/M.
    Shinomiya N, Takemura T, Iwamoto K, Rokutanda M.
    Cytometry; 1997 Apr 01; 27(4):365-73. PubMed ID: 9098629
    [Abstract] [Full Text] [Related]

  • 18. [Abrogation effect of UCN-01 on radiation-induced G2 phase arrest of tumor cells and its mechanism].
    Hui ZG, Li YX, Yang WZ, Yu ZH.
    Ai Zheng; 2005 Jan 01; 24(1):1-6. PubMed ID: 15642191
    [Abstract] [Full Text] [Related]

  • 19. p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells.
    Cayrol C, Knibiehler M, Ducommun B.
    Oncogene; 1998 Jan 22; 16(3):311-20. PubMed ID: 9467956
    [Abstract] [Full Text] [Related]

  • 20. Defective p53 signaling in p53 wild-type tumors attenuates p21waf1 induction and cyclin B repression rendering them sensitive to Chk1 inhibitors that abrogate DNA damage-induced S and G2 arrest.
    Levesque AA, Fanous AA, Poh A, Eastman A.
    Mol Cancer Ther; 2008 Feb 22; 7(2):252-62. PubMed ID: 18281511
    [Abstract] [Full Text] [Related]

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