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Journal Abstract Search

140 related items for PubMed ID: 9220991

  • 1. Affinity radiolabeling identifies peptides associated with the isomerase activity of human type I (placental) 3beta-hydroxysteroid dehydrogenase/isomerase.
    Thomas JL, Evans BW, Strickler RC.
    Biochemistry; 1997 Jul 22; 36(29):9029-34. PubMed ID: 9220991
    [Abstract] [Full Text] [Related]

  • 2. Affinity labeling of human placental 3 beta-hydroxy-delta 5-steroid dehydrogenase and steroid delta-isomerase: evidence for bifunctional catalysis by a different conformation of the same protein for each enzyme activity.
    Thomas JL, Strickler RC, Myers RP, Covey DF.
    Biochemistry; 1992 Jun 23; 31(24):5522-7. PubMed ID: 1610797
    [Abstract] [Full Text] [Related]

  • 3. Affinity labeling in the presence of the reduced diphosphopyridine nucleotide NADH identifies peptides associated with the activities of human placental 3 beta-hydroxy-delta 5-steroid dehydrogenase/isomerase.
    Thomas JL, Nash WE, Crankshaw MW, Strickler RC.
    J Soc Gynecol Investig; 1994 Jun 23; 1(2):155-63. PubMed ID: 9419765
    [Abstract] [Full Text] [Related]

  • 4. Affinity radiolabeling identifies peptides and amino acids associated with substrate binding in human placental 3 beta-hydroxy-delta(5)-steroid dehydrogenase.
    Thomas JL, Nash WE, Myers RP, Crankshaw MW, Strickler RC.
    J Biol Chem; 1993 Sep 05; 268(25):18507-12. PubMed ID: 8360152
    [Abstract] [Full Text] [Related]

  • 5. Site-directed mutagenesis identifies amino acid residues associated with the dehydrogenase and isomerase activities of human type I (placental) 3beta-hydroxysteroid dehydrogenase/isomerase.
    Thomas JL, Evans BW, Blanco G, Mercer RW, Mason JI, Adler S, Nash WE, Isenberg KE, Strickler RC.
    J Steroid Biochem Mol Biol; 1998 Sep 05; 66(5-6):327-34. PubMed ID: 9749838
    [Abstract] [Full Text] [Related]

  • 6. Affinity alkylation of human placental 3 beta-hydroxy-5-ene-steroid dehydrogenase and steroid 5----4-ene-isomerase by 2 alpha-bromoacetoxyprogesterone: evidence for separate dehydrogenase and isomerase sites on one protein.
    Thomas JL, Myers RP, Rosik LO, Strickler RC.
    J Steroid Biochem; 1990 Jun 05; 36(1-2):117-23. PubMed ID: 2362440
    [Abstract] [Full Text] [Related]

  • 7. Human placental 3β-hydroxysteroid dehydrogenase/steroid Δ5,4-isomerase 1: Identity, regulation and environmental inhibitors.
    Zhu Q, Pan P, Chen X, Wang Y, Zhang S, Mo J, Li X, Ge RS.
    Toxicology; 2019 Sep 01; 425():152253. PubMed ID: 31351905
    [Abstract] [Full Text] [Related]

  • 8. An NADH-induced conformational change that mediates the sequential 3 beta-hydroxysteroid dehydrogenase/isomerase activities is supported by affinity labeling and the time-dependent activation of isomerase.
    Thomas JL, Frieden C, Nash WE, Strickler RC.
    J Biol Chem; 1995 Sep 08; 270(36):21003-8. PubMed ID: 7673125
    [Abstract] [Full Text] [Related]

  • 9. Structure, function and tissue-specific gene expression of 3β-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase enzymes in classical and peripheral intracrine steroidogenic tissues.
    Labrie F, Simard J, Luu-The V, Bélanger A, Pelletier G.
    J Steroid Biochem Mol Biol; 1992 Dec 08; 43(8):805-26. PubMed ID: 22217825
    [Abstract] [Full Text] [Related]

  • 10. Thyroid hormone regulation of perch ovarian 3beta-hydroxysteroid dehydrogenase/delta5-delta4-isomerase activity: involvement of a 52-kDa protein.
    Datta M, Nagendra Prasad RJ, Bhattacharya S.
    Gen Comp Endocrinol; 1999 Feb 08; 113(2):212-20. PubMed ID: 10082623
    [Abstract] [Full Text] [Related]

  • 11. Human placental 3beta-hydroxysteroid dehydrogenase: delta5-isomerase. Demonstration of an intermediate in the conversion of 3beta-hydroxypregn-5-en-20-one to pregn-4-ene-3,20-dione.
    Edwards DP, O'Conner JL, Bransome ED, Braselton WE.
    J Biol Chem; 1976 Mar 25; 251(6):1632-8. PubMed ID: 1254588
    [Abstract] [Full Text] [Related]

  • 12. The engineered, cytosolic form of human type I 3beta-hydroxysteroid dehydrogenase/isomerase: purification, characterization and crystallization.
    Thomas JL, Mason JI, Blanco G, Veisaga ML.
    J Mol Endocrinol; 2001 Aug 25; 27(1):77-83. PubMed ID: 11463578
    [Abstract] [Full Text] [Related]

  • 13. Creation of a fully active, cytosolic form of human type I 3beta-hydroxysteroid dehydrogenase/isomerase by the deletion of a membrane-spanning domain.
    Thomas JL, Evans BW, Blanco G, Mason JI, Strickler RC.
    J Mol Endocrinol; 1999 Oct 25; 23(2):231-9. PubMed ID: 10514560
    [Abstract] [Full Text] [Related]

  • 14. Bovine adrenal 3beta-hydroxysteroid dehydrogenase (E.C. 1.1.1. 145)/5-ene-4-ene isomerase (E.C. 5.3.3.1): characterization and its inhibition by isoflavones.
    Wong CK, Keung WM.
    J Steroid Biochem Mol Biol; 1999 Dec 31; 71(5-6):191-202. PubMed ID: 10704908
    [Abstract] [Full Text] [Related]

  • 15. Structure/function relationships responsible for the kinetic differences between human type 1 and type 2 3beta-hydroxysteroid dehydrogenase and for the catalysis of the type 1 activity.
    Thomas JL, Mason JI, Brandt S, Spencer BR, Norris W.
    J Biol Chem; 2002 Nov 08; 277(45):42795-801. PubMed ID: 12205101
    [Abstract] [Full Text] [Related]

  • 16. 3 beta-hydroxysteroid dehydrogenase isomerase (3beta-HSD) activity in the rat sciatic nerve: kinetic analysis and regulation by steroids.
    Coirini H, Gouézou M, Delespierre B, Schumacher M, Guennoun R.
    J Steroid Biochem Mol Biol; 2003 May 08; 85(1):89-94. PubMed ID: 12798361
    [Abstract] [Full Text] [Related]

  • 17. Differences in substrate and inhibitor kinetics of human type 1 and type 2 3beta-hydroxysteroid dehydrogenase are explained by the type 1 mutant, H156Y.
    Thomas JL, Mason JI, Brandt S, Norris W.
    Endocr Res; 2002 Nov 08; 28(4):471-5. PubMed ID: 12530651
    [Abstract] [Full Text] [Related]

  • 18. Molecular biology of the 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase gene family.
    Simard J, Ricketts ML, Gingras S, Soucy P, Feltus FA, Melner MH.
    Endocr Rev; 2005 Jun 08; 26(4):525-82. PubMed ID: 15632317
    [Abstract] [Full Text] [Related]

  • 19. Affinity labeling identifies histidine at the active site of human placental 3 beta-hydroxysteroid dehydrogenase and steroid 5-->4-ene-isomerase.
    Strickler RC, Thomas JL.
    Am J Obstet Gynecol; 1993 Apr 08; 168(4):1216-21; discussion 1221-2. PubMed ID: 8475968
    [Abstract] [Full Text] [Related]

  • 20. Structure/function relationships responsible for coenzyme specificity and the isomerase activity of human type 1 3 beta-hydroxysteroid dehydrogenase/isomerase.
    Thomas JL, Duax WL, Addlagatta A, Brandt S, Fuller RR, Norris W.
    J Biol Chem; 2003 Sep 12; 278(37):35483-90. PubMed ID: 12832414
    [Abstract] [Full Text] [Related]

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