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404 related items for PubMed ID: 9223571

  • 1. Antagonism of N-methyl-D-aspartate receptors by sigma site ligands: potency, subtype-selectivity and mechanisms of inhibition.
    Whittemore ER, Ilyin VI, Woodward RM.
    J Pharmacol Exp Ther; 1997 Jul; 282(1):326-38. PubMed ID: 9223571
    [Abstract] [Full Text] [Related]

  • 2. Subtype-selective inhibition of N-methyl-D-aspartate receptors by haloperidol.
    Ilyin VI, Whittemore ER, Guastella J, Weber E, Woodward RM.
    Mol Pharmacol; 1996 Dec; 50(6):1541-50. PubMed ID: 8967976
    [Abstract] [Full Text] [Related]

  • 3. Characterization of haloperidol and trifluperidol as subtype-selective N-methyl-D-aspartate (NMDA) receptor antagonists using [3H]TCP and [3H]ifenprodil binding in rat brain membranes.
    Coughenour LL, Cordon JJ.
    J Pharmacol Exp Ther; 1997 Feb; 280(2):584-92. PubMed ID: 9023267
    [Abstract] [Full Text] [Related]

  • 4. Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors.
    Williams K.
    Mol Pharmacol; 1993 Oct; 44(4):851-9. PubMed ID: 7901753
    [Abstract] [Full Text] [Related]

  • 5. Differing effects of N-methyl-D-aspartate receptor subtype selective antagonists on dyskinesias in levodopa-treated 1-methyl-4-phenyl-tetrahydropyridine monkeys.
    Blanchet PJ, Konitsiotis S, Whittemore ER, Zhou ZL, Woodward RM, Chase TN.
    J Pharmacol Exp Ther; 1999 Sep; 290(3):1034-40. PubMed ID: 10454475
    [Abstract] [Full Text] [Related]

  • 6. Structure-activity relationship of N-(phenylalkyl)cinnamides as novel NR2B subtype-selective NMDA receptor antagonists.
    Tamiz AP, Cai SX, Zhou ZL, Yuen PW, Schelkun RM, Whittemore ER, Weber E, Woodward RM, Keana JF.
    J Med Chem; 1999 Aug 26; 42(17):3412-20. PubMed ID: 10464027
    [Abstract] [Full Text] [Related]

  • 7. Structure-activity relationships for a series of bis(phenylalkyl)amines: potent subtype-selective inhibitors of N-methyl-D-aspartate receptors.
    Tamiz AP, Whittemore ER, Zhou ZL, Huang JC, Drewe JA, Chen JC, Cai SX, Weber E, Woodward RM, Keana JF.
    J Med Chem; 1998 Aug 27; 41(18):3499-506. PubMed ID: 9719603
    [Abstract] [Full Text] [Related]

  • 8. Use of trifluoroperazine isolates a [(3)H]Ifenprodil binding site in rat brain membranes with the pharmacology of the voltage-independent ifenprodil site on N-methyl-D-aspartate receptors containing NR2B subunits.
    Coughenour LL, Barr BM.
    J Pharmacol Exp Ther; 2001 Jan 27; 296(1):150-9. PubMed ID: 11123375
    [Abstract] [Full Text] [Related]

  • 9. State-dependent NMDA receptor antagonism by Ro 8-4304, a novel NR2B selective, non-competitive, voltage-independent antagonist.
    Kew JN, Trube G, Kemp JA.
    Br J Pharmacol; 1998 Feb 27; 123(3):463-72. PubMed ID: 9504387
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and pharmacological evaluation of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methylguanidines as N-methyl-D-aspartate receptor ion-channel blockers.
    Hu LY, Guo J, Magar SS, Fischer JB, Burke-Howie KJ, Durant GJ.
    J Med Chem; 1997 Dec 19; 40(26):4281-9. PubMed ID: 9435897
    [Abstract] [Full Text] [Related]

  • 11. Adenosine triphosphate acts as both a competitive antagonist and a positive allosteric modulator at recombinant N-methyl-D-aspartate receptors.
    Kloda A, Clements JD, Lewis RJ, Adams DJ.
    Mol Pharmacol; 2004 Jun 19; 65(6):1386-96. PubMed ID: 15155832
    [Abstract] [Full Text] [Related]

  • 12. Subtype-selective N-methyl-D-aspartate receptor antagonists: synthesis and biological evaluation of 1-(arylalkynyl)-4-benzylpiperidines.
    Wright JL, Gregory TF, Bigge CF, Boxer PA, Serpa K, Meltzer LT, Wise LD, Cai SX, Hawkinson JE, Konkoy CS, Whittemore ER, Woodward RM, Zhou ZL.
    J Med Chem; 1999 Jul 01; 42(13):2469-77. PubMed ID: 10395488
    [Abstract] [Full Text] [Related]

  • 13. Modulation by sigma ligands of intracellular free Ca++ mobilization by N-methyl-D-aspartate in primary culture of rat frontal cortical neurons.
    Hayashi T, Kagaya A, Takebayashi M, Shimizu M, Uchitomi Y, Motohashi N, Yamawaki S.
    J Pharmacol Exp Ther; 1995 Oct 01; 275(1):207-14. PubMed ID: 7562551
    [Abstract] [Full Text] [Related]

  • 14. Antagonist properties of the stereoisomers of ifenprodil at NR1A/NR2A and NR1A/NR2B subtypes of the NMDA receptor expressed in Xenopus oocytes.
    Avenet P, Léonardon J, Besnard F, Graham D, Frost J, Depoortere H, Langer SZ, Scatton B.
    Eur J Pharmacol; 1996 Jan 25; 296(2):209-13. PubMed ID: 8838458
    [Abstract] [Full Text] [Related]

  • 15. Cloning and functional characterization of human heteromeric N-methyl-D-aspartate receptors.
    Hess SD, Daggett LP, Crona J, Deal C, Lu CC, Urrutia A, Chavez-Noriega L, Ellis SB, Johnson EC, Veliçelebi G.
    J Pharmacol Exp Ther; 1996 Aug 25; 278(2):808-16. PubMed ID: 8768735
    [Abstract] [Full Text] [Related]

  • 16. Subtype-selective antagonism of NMDA receptors by nylidrin.
    Whittemore ER, Ilyin VI, Konkoy CS, Woodward RM.
    Eur J Pharmacol; 1997 Oct 22; 337(2-3):197-208. PubMed ID: 9430414
    [Abstract] [Full Text] [Related]

  • 17. Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells.
    Priestley T, Laughton P, Myers J, Le Bourdellés B, Kerby J, Whiting PJ.
    Mol Pharmacol; 1995 Nov 22; 48(5):841-8. PubMed ID: 7476914
    [Abstract] [Full Text] [Related]

  • 18. Selective antagonism of native and cloned kainate and NMDA receptors by polyamine-containing toxins.
    Brackley PT, Bell DR, Choi SK, Nakanishi K, Usherwood PN.
    J Pharmacol Exp Ther; 1993 Sep 22; 266(3):1573-80. PubMed ID: 7690404
    [Abstract] [Full Text] [Related]

  • 19. N-methyl-D-aspartate receptor channel block by the enantiomeric 6,7-benzomorphans BIII 277 CL and BIII 281 CL.
    Grauert M, Rho JM, Subramaniam S, Rogawski MA.
    J Pharmacol Exp Ther; 1998 May 22; 285(2):767-76. PubMed ID: 9580625
    [Abstract] [Full Text] [Related]

  • 20. The anticonvulsant actions of sigma receptor ligands in the Mg2+-free model of epileptiform activity in rat hippocampal slices.
    Thurgur C, Church J.
    Br J Pharmacol; 1998 Jul 22; 124(5):917-29. PubMed ID: 9692777
    [Abstract] [Full Text] [Related]

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