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170 related items for PubMed ID: 9228034

  • 1. Identification of common ligand binding determinants of the insulin and insulin-like growth factor 1 receptors. Insights into mechanisms of ligand binding.
    Mynarcik DC, Williams PF, Schaffer L, Yu GQ, Whittaker J.
    J Biol Chem; 1997 Jul 25; 272(30):18650-5. PubMed ID: 9228034
    [Abstract] [Full Text] [Related]

  • 2. Analog binding properties of insulin receptor mutants. Identification of amino acids interacting with the COOH terminus of the B-chain of the insulin molecule.
    Mynarcik DC, Williams PF, Schaffer L, Yu GQ, Whittaker J.
    J Biol Chem; 1997 Jan 24; 272(4):2077-81. PubMed ID: 8999905
    [Abstract] [Full Text] [Related]

  • 3. Alanine scanning mutagenesis of a type 1 insulin-like growth factor receptor ligand binding site.
    Whittaker J, Groth AV, Mynarcik DC, Pluzek L, Gadsbøll VL, Whittaker LJ.
    J Biol Chem; 2001 Nov 23; 276(47):43980-6. PubMed ID: 11500492
    [Abstract] [Full Text] [Related]

  • 4. Mutations at positions 11 and 60 of insulin-like growth factor 1 reveal differences between its interactions with the type I insulin-like-growth-factor receptor and the insulin receptor.
    Hodgson DR, May FE, Westley BR.
    Eur J Biochem; 1995 Oct 01; 233(1):299-309. PubMed ID: 7588759
    [Abstract] [Full Text] [Related]

  • 5. Characterization of the functional insulin binding epitopes of the full-length insulin receptor.
    Whittaker J, Whittaker L.
    J Biol Chem; 2005 Jun 03; 280(22):20932-6. PubMed ID: 15799978
    [Abstract] [Full Text] [Related]

  • 6. Structural determinants of ligand recognition by type I insulin-like growth factor receptors: use of semisynthetic insulin analog probes.
    Cara JF, Nakagawa SH, Tager HS.
    Endocrinology; 1988 Jun 03; 122(6):2881-7. PubMed ID: 2967179
    [Abstract] [Full Text] [Related]

  • 7. Signaling-competent receptor chimeras allow mapping of major insulin receptor binding domain determinants.
    Schumacher R, Soos MA, Schlessinger J, Brandenburg D, Siddle K, Ullrich A.
    J Biol Chem; 1993 Jan 15; 268(2):1087-94. PubMed ID: 7678247
    [Abstract] [Full Text] [Related]

  • 8. Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation.
    Kertisová A, Žáková L, Macháčková K, Marek A, Šácha P, Pompach P, Jiráček J, Selicharová I.
    Open Biol; 2023 Nov 15; 13(11):230142. PubMed ID: 37935358
    [Abstract] [Full Text] [Related]

  • 9. N-terminal deletion mutants of insulin-like growth factor-II (IGF-II) show Thr7 and Leu8 important for binding to insulin and IGF-I receptors and Leu8 critical for all IGF-II functions.
    Hashimoto R, Fujiwara H, Higashihashi N, Enjoh-Kimura T, Terasawa H, Fujita-Yamaguchi Y, Inagaki F, Perdue JF, Sakano K.
    J Biol Chem; 1995 Jul 28; 270(30):18013-8. PubMed ID: 7629109
    [Abstract] [Full Text] [Related]

  • 10. Alanine-scanning mutagenesis of a C-terminal ligand binding domain of the insulin receptor alpha subunit.
    Mynarcik DC, Yu GQ, Whittaker J.
    J Biol Chem; 1996 Feb 02; 271(5):2439-42. PubMed ID: 8576204
    [Abstract] [Full Text] [Related]

  • 11. [The structural organization of binding determinants in insulin-like growth factor-I (IGF-I) molecule].
    Kolychev AP.
    Zh Evol Biokhim Fiziol; 2010 Feb 02; 46(1):74-94. PubMed ID: 20297673
    [Abstract] [Full Text] [Related]

  • 12. Comparison of the functional insulin binding epitopes of the A and B isoforms of the insulin receptor.
    Whittaker J, Sørensen H, Gadsbøll VL, Hinrichsen J.
    J Biol Chem; 2002 Dec 06; 277(49):47380-4. PubMed ID: 12270939
    [Abstract] [Full Text] [Related]

  • 13. Relationship between alpha subunit ligand occupancy and beta subunit autophosphorylation in insulin/insulin-like growth factor-1 hybrid receptors.
    Frattali AL, Pessin JE.
    J Biol Chem; 1993 Apr 05; 268(10):7393-400. PubMed ID: 8463272
    [Abstract] [Full Text] [Related]

  • 14. High-affinity insulin binding: insulin interacts with two receptor ligand binding sites.
    Whittaker L, Hao C, Fu W, Whittaker J.
    Biochemistry; 2008 Dec 02; 47(48):12900-9. PubMed ID: 18991400
    [Abstract] [Full Text] [Related]

  • 15. A single-chain insulin-like growth factor I/insulin hybrid binds with high affinity to the insulin receptor.
    Kristensen C, Andersen AS, Hach M, Wiberg FC, Schäffer L, Kjeldsen T.
    Biochem J; 1995 Feb 01; 305 ( Pt 3)(Pt 3):981-6. PubMed ID: 7848300
    [Abstract] [Full Text] [Related]

  • 16. Alanine scanning of a putative receptor binding surface of insulin-like growth factor-I.
    Gauguin L, Delaine C, Alvino CL, McNeil KA, Wallace JC, Forbes BE, De Meyts P.
    J Biol Chem; 2008 Jul 25; 283(30):20821-9. PubMed ID: 18502759
    [Abstract] [Full Text] [Related]

  • 17. Insulin and insulin-like growth factor-1 binding specificity is determined by distinct regions of their cognate receptors.
    Schumacher R, Mosthaf L, Schlessinger J, Brandenburg D, Ullrich A.
    J Biol Chem; 1991 Oct 15; 266(29):19288-95. PubMed ID: 1655782
    [Abstract] [Full Text] [Related]

  • 18. Structural analogs of human insulin-like growth factor I with reduced affinity for serum binding proteins and the type 2 insulin-like growth factor receptor.
    Bayne ML, Applebaum J, Chicchi GG, Hayes NS, Green BG, Cascieri MA.
    J Biol Chem; 1988 May 05; 263(13):6233-9. PubMed ID: 2966152
    [Abstract] [Full Text] [Related]

  • 19. Functional characterization of hybrid receptors composed of a truncated insulin receptor and wild type insulin-like growth factor 1 or insulin receptors.
    Langlois WJ, Sasaoka T, Yip CC, Olefsky JM.
    Endocrinology; 1995 May 05; 136(5):1978-86. PubMed ID: 7720646
    [Abstract] [Full Text] [Related]

  • 20. Structural basis for the lower affinity of the insulin-like growth factors for the insulin receptor.
    Gauguin L, Klaproth B, Sajid W, Andersen AS, McNeil KA, Forbes BE, De Meyts P.
    J Biol Chem; 2008 Feb 01; 283(5):2604-13. PubMed ID: 18048361
    [Abstract] [Full Text] [Related]

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