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Journal Abstract Search

135 related items for PubMed ID: 9258356

  • 1. 5-(Piperidin-2-yl)- and 5-(homopiperidin-2-yl)-1,4-benzodiazepines: high-affinity, basic ligands for the cholecystokinin-B receptor.
    Castro JL, Broughton HB, Russell MG, Rathbone D, Watt AP, Ball RG, Chapman KL, Patel S, Smith AJ, Marshall GR, Matassa VG.
    J Med Chem; 1997 Aug 01; 40(16):2491-501. PubMed ID: 9258356
    [Abstract] [Full Text] [Related]

  • 2. Development of 1,4-benzodiazepine cholecystokinin type B antagonists.
    Bock MG, DiPardo RM, Evans BE, Rittle KE, Whitter WL, Garsky VM, Gilbert KF, Leighton JL, Carson KL, Mellin EC.
    J Med Chem; 1993 Dec 24; 36(26):4276-92. PubMed ID: 8277510
    [Abstract] [Full Text] [Related]

  • 3. Biological properties of the benzodiazepine amidine derivative L-740,093, a cholecystokinin-B/gastrin receptor antagonist with high affinity in vitro and high potency in vivo.
    Patel S, Smith AJ, Chapman KL, Fletcher AE, Kemp JA, Marshall GR, Hargreaves RJ, Ryecroft W, Iversen LL, Iversen SD.
    Mol Pharmacol; 1994 Nov 24; 46(5):943-8. PubMed ID: 7969084
    [Abstract] [Full Text] [Related]

  • 4. Benzodiazepine gastrin and brain cholecystokinin receptor ligands: L-365,260.
    Bock MG, DiPardo RM, Evans BE, Rittle KE, Whitter WL, Veber DE, Anderson PS, Freidinger RM.
    J Med Chem; 1989 Jan 24; 32(1):13-6. PubMed ID: 2909725
    [No Abstract] [Full Text] [Related]

  • 5. Pharmacological profile of (R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo- 5-phenyl-1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea (YM022), a new potent and selective gastrin/cholecystokinin-B receptor antagonist, in vitro and in vivo.
    Nishida A, Miyata K, Tsutsumi R, Yuki H, Akuzawa S, Kobayashi A, Kamato T, Ito H, Yamano M, Katuyama Y.
    J Pharmacol Exp Ther; 1994 May 24; 269(2):725-31. PubMed ID: 7910212
    [Abstract] [Full Text] [Related]

  • 6. Quantitative structure-activity relationship study on some nonpeptidal cholecystokinin antagonists.
    Sinha J, Kurup A, Paleti A, Gupta SP.
    Bioorg Med Chem; 1999 Jun 24; 7(6):1127-30. PubMed ID: 10428383
    [Abstract] [Full Text] [Related]

  • 7. Selective non-peptide ligands for an accommodating peptide receptor. Imidazobenzodiazepines as potent cholecystokinin type B receptor antagonists.
    Bock MG, DiPardo RM, Newton RC, Bergman JM, Veber DF, Freedman SB, Smith AJ, Chapman KL, Patel S, Kemp JA.
    Bioorg Med Chem; 1994 Sep 24; 2(9):987-98. PubMed ID: 7712133
    [Abstract] [Full Text] [Related]

  • 8. Potent and subtype-selective CCK-B/gastrin receptor antagonists: 2,4-dioxo-1,5-benzodiazepines with a plane of symmetry.
    Hagishita S, Seno K, Kamata S, Haga N, Ishihara Y, Ishikawa M, Shimamura M.
    Bioorg Med Chem; 1997 Jul 24; 5(7):1433-46. PubMed ID: 9377103
    [Abstract] [Full Text] [Related]

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  • 10. Analysis of the behaviour of selected CCKB/gastrin receptor antagonists in radioligand binding assays performed in mouse and rat cerebral cortex.
    Harper EA, Griffin EP, Shankley NP, Black JW.
    Br J Pharmacol; 1999 Mar 24; 126(6):1496-503. PubMed ID: 10217545
    [Abstract] [Full Text] [Related]

  • 11.
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  • 12. Peptide/benzodiazepine hybrids as ligands of CCK(A) and CCK(B) receptors.
    Escherich A, Lutz J, Escrieut C, Fourmy D, van Neuren AS, Müller G, Schafferhans A, Klebe G, Moroder L.
    Biopolymers; 1999 Mar 24; 56(2):55-76. PubMed ID: 11592053
    [Abstract] [Full Text] [Related]

  • 13. Dual CCK-A and CCK-B receptor antagonists (II). Preparation and structure activity relationships of 5-alkyl-9-methyl-1,4-benzodiazepines and discovery of FR208419.
    Tabuchi S, Ito H, Sogabe H, Kuno M, Kinoshita T, Katumi I, Yamamoto N, Mitsui H, Satoh Y.
    Chem Pharm Bull (Tokyo); 2000 Jan 24; 48(1):1-15. PubMed ID: 10705468
    [Abstract] [Full Text] [Related]

  • 14. Controlled modification of acidity in cholecystokinin B receptor antagonists: N-(1,4-benzodiazepin-3-yl)-N'-[3-(tetrazol-5-ylamino) phenyl]ureas.
    Castro JL, Ball RG, Broughton HB, Russell MG, Rathbone D, Watt AP, Baker R, Chapman KL, Fletcher AE, Patel S, Smith AJ, Marshall GR, Ryecroft W, Matassa VG.
    J Med Chem; 1996 Feb 16; 39(4):842-9. PubMed ID: 8632408
    [Abstract] [Full Text] [Related]

  • 15. CCK receptor antagonists.
    Dunlop J.
    Gen Pharmacol; 1998 Oct 16; 31(4):519-24. PubMed ID: 9792209
    [Abstract] [Full Text] [Related]

  • 16. Mutations within the cholecystokinin-B/gastrin receptor ligand 'pocket' interconvert the functions of nonpeptide agonists and antagonists.
    Bläker M, Ren Y, Gordon MC, Hsu JE, Beinborn M, Kopin AS.
    Mol Pharmacol; 1998 Nov 16; 54(5):857-63. PubMed ID: 9804620
    [Abstract] [Full Text] [Related]

  • 17. Recent advances in the chemistry of cholecystokinin receptor ligands (agonists and antagonists).
    de Tullio P, Delarge J, Pirotte B.
    Curr Med Chem; 1999 Jun 16; 6(6):433-55. PubMed ID: 10213792
    [Abstract] [Full Text] [Related]

  • 18. Novel 1,5-benzodiazepines as CCK-B ligands. Effect of aryl-carbamic substituents at the C-3 position together with halogen substitution on the benzo-fused ring.
    Tranquillini ME, Cassarà PG, Corsi M, Curotto G, Donati D, Finizia G, Pentassuglia G, Polinelli S, Tarzia G, Ursini A, van Amsterdam FT.
    Arch Pharm (Weinheim); 1997 Nov 16; 330(11):353-7. PubMed ID: 9431027
    [No Abstract] [Full Text] [Related]

  • 19. Small synthetic ligands of the cholecystokinin-B/gastrin receptor can mimic the function of endogenous peptide hormones.
    Beinborn M, Chen C, DeMeo L, McBride EW, Kopin AS.
    Yale J Biol Med; 1998 Nov 16; 71(3-4):337-46. PubMed ID: 10461364
    [Abstract] [Full Text] [Related]

  • 20. Cholecystokinin-A receptor ligands based on the kappa-opioid agonist tifluadom.
    Bock MG, DiPardo RM, Evans BE, Rittle KE, Whitter WL, Veber DF, Freidinger RM, Chang RS, Chen TB, Lotti VJ.
    J Med Chem; 1990 Jan 16; 33(1):450-5. PubMed ID: 2153212
    [Abstract] [Full Text] [Related]

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