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Journal Abstract Search
138 related items for PubMed ID: 9259409
1. CEP-751 inhibits TRK receptor tyrosine kinase activity in vitro exhibits anti-tumor activity. Camoratto AM, Jani JP, Angeles TS, Maroney AC, Sanders CY, Murakata C, Neff NT, Vaught JL, Isaacs JT, Dionne CA. Int J Cancer; 1997 Aug 07; 72(4):673-9. PubMed ID: 9259409 [Abstract] [Full Text] [Related]
2. Sustained in vivo regression of Dunning H rat prostate cancers treated with combinations of androgen ablation and Trk tyrosine kinase inhibitors, CEP-751 (KT-6587) or CEP-701 (KT-5555). George DJ, Dionne CA, Jani J, Angeles T, Murakata C, Lamb J, Isaacs JT. Cancer Res; 1999 May 15; 59(10):2395-401. PubMed ID: 10344749 [Abstract] [Full Text] [Related]
3. Cell cycle-independent death of prostate adenocarcinoma is induced by the trk tyrosine kinase inhibitor CEP-751 (KT6587). Dionne CA, Camoratto AM, Jani JP, Emerson E, Neff N, Vaught JL, Murakata C, Djakiew D, Lamb J, Bova S, George D, Isaacs JT. Clin Cancer Res; 1998 Aug 15; 4(8):1887-98. PubMed ID: 9717816 [Abstract] [Full Text] [Related]
4. Gö 6976 is a potent inhibitor of neurotrophin-receptor intrinsic tyrosine kinase. Behrens MM, Strasser U, Choi DW. J Neurochem; 1999 Mar 15; 72(3):919-24. PubMed ID: 10037462 [Abstract] [Full Text] [Related]
5. K-252b potentiation of neurotrophin-3 is trkA specific in cells lacking p75NTR. Maroney AC, Sanders C, Neff NT, Dionne CA. J Neurochem; 1997 Jan 15; 68(1):88-94. PubMed ID: 8978713 [Abstract] [Full Text] [Related]
6. Oncogenic activation of the tyrosine kinase domain of the human trk proto-oncogene by fusion to a cell adhesion molecule. Albor A, Thraves PJ, Dritschilo A, Notario V. Oncogene; 1996 Oct 17; 13(8):1755-63. PubMed ID: 8895522 [Abstract] [Full Text] [Related]
7. Kinetics of trkA tyrosine kinase activity and inhibition by K-252a. Angeles TS, Yang SX, Steffler C, Dionne CA. Arch Biochem Biophys; 1998 Jan 15; 349(2):267-74. PubMed ID: 9448714 [Abstract] [Full Text] [Related]
8. Suppression of p140trkA does not abolish nerve growth factor-mediated rescue of serum-free PC12 cells. Taglialatela G, Hibbert CJ, Hutton LA, Werrbach-Perez K, Perez-Polo JR. J Neurochem; 1996 May 15; 66(5):1826-35. PubMed ID: 8780007 [Abstract] [Full Text] [Related]
9. Transphosphorylation of the neurotrophin Trk receptors. Canossa M, Rovelli G, ShooterEM. J Biol Chem; 1996 Mar 08; 271(10):5812-8. PubMed ID: 8621450 [Abstract] [Full Text] [Related]
11. Inhibition of phosphorylation of TrkB and TrkC and their signal transduction by alpha2-macroglobulin. Hu YQ, Koo PH. J Neurochem; 1998 Jul 17; 71(1):213-20. PubMed ID: 9648868 [Abstract] [Full Text] [Related]
12. K252a is a selective inhibitor of the tyrosine protein kinase activity of the trk family of oncogenes and neurotrophin receptors. Tapley P, Lamballe F, Barbacid M. Oncogene; 1992 Feb 17; 7(2):371-81. PubMed ID: 1312698 [Abstract] [Full Text] [Related]
13. The novel Trk receptor tyrosine kinase inhibitor CEP-701 (KT-5555) exhibits antitumor efficacy against human pancreatic carcinoma (Panc1) xenograft growth and in vivo invasiveness. Miknyoczki SJ, Dionne CA, Klein-Szanto AJ, Ruggeri BA. Ann N Y Acad Sci; 1999 Jun 30; 880():252-62. PubMed ID: 10415871 [Abstract] [Full Text] [Related]
14. Expression of TRK-T1 oncogene induces differentiation of PC12 cells. Greco A, Orlandi R, Mariani C, Miranda C, Borrello MG, Cattaneo A, Pagliardini S, Pierotti MA. Cell Growth Differ; 1993 Jul 30; 4(7):539-46. PubMed ID: 8398895 [Abstract] [Full Text] [Related]
15. The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth. Ashcroft M, Stephens RM, Hallberg B, Downward J, Kaplan DR. Oncogene; 1999 Aug 12; 18(32):4586-97. PubMed ID: 10467403 [Abstract] [Full Text] [Related]
16. Analysis of the trk NGF receptor tyrosine kinase using recombinant fusion proteins. Horvath CM, Wolven A, Machadeo D, Huber J, Boter L, Benedetti M, Hempstead B, Chao MV. J Cell Sci Suppl; 1993 Aug 12; 17():223-8. PubMed ID: 8144701 [Abstract] [Full Text] [Related]
17. Extended ceramide exposure activates the trkA receptor by increasing receptor homodimer formation. MacPhee I, Barker PA. J Neurochem; 1999 Apr 12; 72(4):1423-30. PubMed ID: 10098845 [Abstract] [Full Text] [Related]
18. TrkA mediates the nerve growth factor-induced intracellular calcium accumulation. De Bernardi MA, Rabins SJ, Colangelo AM, Brooker G, Mocchetti I. J Biol Chem; 1996 Mar 15; 271(11):6092-8. PubMed ID: 8626395 [Abstract] [Full Text] [Related]
19. Nerve growth factor induced stimulation of Ras requires Trk interaction with Shc but does not involve phosphoinositide 3-OH kinase. Hallberg B, Ashcroft M, Loeb DM, Kaplan DR, Downward J. Oncogene; 1998 Aug 13; 17(6):691-7. PubMed ID: 9715270 [Abstract] [Full Text] [Related]
20. Phosphotyrosine residues in the nerve-growth-factor receptor (Trk-A). Their role in the activation of inositolphospholipid metabolism and protein kinase cascades in phaeochromocytoma (PC12) cells. Baxter RM, Cohen P, Obermeier A, Ullrich A, Downes CP, Doza YN. Eur J Biochem; 1995 Nov 15; 234(1):84-91. PubMed ID: 8529673 [Abstract] [Full Text] [Related] Page: [Next] [New Search]