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Journal Abstract Search

48 related items for PubMed ID: 925966

  • 1. Effect of ring substitution on the metabolic fate and anti-inflammatory activity of some prodolic acid analogs.
    Robinson WT, Martel RR, Ferdinandi E, Kraml M.
    J Pharmacol Exp Ther; 1977 Dec; 203(3):729-35. PubMed ID: 925966
    [Abstract] [Full Text] [Related]

  • 2. Prodolic acid: analysis and disposition studies in rats and dogs.
    Robinson WT, Kraml M, Greselin E, Dvornik D.
    Xenobiotica; 1977 Jun; 7(6):329-37. PubMed ID: 305689
    [Abstract] [Full Text] [Related]

  • 3. Disposition of etodolac, other anti-inflammatory pyranoindole-1-acetic acids and furobufen in normal and adjuvant arthritic rats.
    Ferdinandi ES, Cayen MN, Pace-Asciak C.
    J Pharmacol Exp Ther; 1982 Feb; 220(2):417-26. PubMed ID: 6460096
    [No Abstract] [Full Text] [Related]

  • 4. Chemistry and antiinflammatory activities of prodolic-acid and related 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-alkanoic acids. 1.
    Demerson CA, Humber LG, Dobson TA, Martel RR.
    J Med Chem; 1975 Feb; 18(2):189-91. PubMed ID: 1120985
    [Abstract] [Full Text] [Related]

  • 5. Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38alpha inhibitor: identification of an active metabolite in preclinical species and human liver microsomes.
    Kalgutkar AS, Hatch HL, Kosea F, Nguyen HT, Choo EF, McClure KF, Taylor TJ, Henne KR, Kuperman AV, Dombroski MA, Letavic MA.
    Biopharm Drug Dispos; 2006 Nov; 27(8):371-86. PubMed ID: 16944451
    [Abstract] [Full Text] [Related]

  • 6. Indol-3-yl-tetramethylcyclopropyl ketones: effects of indole ring substitution on CB2 cannabinoid receptor activity.
    Frost JM, Dart MJ, Tietje KR, Garrison TR, Grayson GK, Daza AV, El-Kouhen OF, Miller LN, Li L, Yao BB, Hsieh GC, Pai M, Zhu CZ, Chandran P, Meyer MD.
    J Med Chem; 2008 Mar 27; 51(6):1904-12. PubMed ID: 18311894
    [Abstract] [Full Text] [Related]

  • 7. [Chemical structure and anti-inflammatory activity in the group of substituted indole-3-acetic acids (author's transl)].
    Boltze KH, Brendler O, Jacobi H, Opitz W, Raddatz S, Seidel PR, Vollbrecht D.
    Arzneimittelforschung; 1980 Mar 27; 30(8A):1314-25. PubMed ID: 7191301
    [Abstract] [Full Text] [Related]

  • 8. Disposition of the dipeptidyl peptidase 4 inhibitor sitagliptin in rats and dogs.
    Beconi MG, Reed JR, Teffera Y, Xia YQ, Kochansky CJ, Liu DQ, Xu S, Elmore CS, Ciccotto S, Hora DF, Stearns RA, Vincent SH.
    Drug Metab Dispos; 2007 Apr 27; 35(4):525-32. PubMed ID: 17220241
    [Abstract] [Full Text] [Related]

  • 9. Anti-inflammatory effect of antidiabetic thiazolidinediones prevents bone resorption rather than cartilage changes in experimental polyarthritis.
    Koufany M, Moulin D, Bianchi A, Muresan M, Sebillaud S, Netter P, Weryha G, Jouzeau JY.
    Arthritis Res Ther; 2008 Apr 27; 10(1):R6. PubMed ID: 18199331
    [Abstract] [Full Text] [Related]

  • 10. Some pharmacological effects of prodolic acid, a new anti-inflammatory compound, indicative of inhibition of prostaglandin synthesis.
    Greenberg R.
    Can J Physiol Pharmacol; 1975 Feb 27; 53(1):186-9. PubMed ID: 1139444
    [Abstract] [Full Text] [Related]

  • 11. The pharmacological profile of 2-(8-methyl-10,11-dihydro-11-oxodibenz[b,f]oxepin-2-yl)propionic acid (AD-1590), a new non-steroidal anti-inflammatory agent with potent antipyretic activity.
    Nakamura H, Yokoyama Y, Motoyoshi S, Ishii K, Imazu C, Seto Y, Kadokawa T, Shimizu M.
    Arzneimittelforschung; 1983 Feb 27; 33(11):1555-69. PubMed ID: 6607053
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and serotonergic activity of substituted 2, N-benzylcarboxamido-5-(2-ethyl-1-dioxoimidazolidinyl)-N, N-dimethyltryptamine derivatives: novel antagonists for the vascular 5-HT(1B)-like receptor.
    Moloney GP, Martin GR, Mathews N, Milne A, Hobbs H, Dodsworth S, Sang PY, Knight C, Williams M, Maxwell M, Glen RC.
    J Med Chem; 1999 Jul 15; 42(14):2504-26. PubMed ID: 10411472
    [Abstract] [Full Text] [Related]

  • 13. Interaction of indole derivatives with monoamine oxidase A and B. Studies on the structure-inhibitory activity relationship.
    Medvedev AE, Ivanov AS, Kamyshanskaya NS, Kirkel AZ, Moskvitina TA, Gorkin VZ, Li NY, Marshakov VYu.
    Biochem Mol Biol Int; 1995 May 15; 36(1):113-22. PubMed ID: 7663405
    [Abstract] [Full Text] [Related]

  • 14. Discovery of 4-[1-[([1-[4-(trifluoromethyl)benzyl]-1H-indol-7-yl]carbonyl)amino]cyclopropyl]benzoic acid (MF-766), a highly potent and selective EP4 antagonist for treating inflammatory pain.
    Colucci J, Boyd M, Berthelette C, Chiasson JF, Wang Z, Ducharme Y, Friesen R, Wrona M, Levesque JF, Denis D, Mathieu MC, Stocco R, Therien AG, Clarke P, Rowland S, Xu D, Han Y.
    Bioorg Med Chem Lett; 2010 Jun 15; 20(12):3760-3. PubMed ID: 20471829
    [Abstract] [Full Text] [Related]

  • 15. Etodolic acid and related compounds. Chemistry and antiinflammatory actions of some potent di- and trisubstituted 1, 3, 4, 9-tetrahydropyrano[3, 4-b]indole-1-acetic acids.
    Martel RR, Demerson CA, Humber LG, Philipp AH.
    J Med Chem; 1976 Mar 15; 19(3):391-5. PubMed ID: 1255663
    [Abstract] [Full Text] [Related]

  • 16. Investigation of 1,3,4,9-Tetrahydro-1-popylpyrano [3,4-b] indole-1-acetic acid (prodolic acid), a new non-steroidal anti-inflammatory agent, in rats.
    Martel RR, Klicius J, Herr F.
    Agents Actions; 1974 Dec 15; 4(5):370-6. PubMed ID: 4463721
    [No Abstract] [Full Text] [Related]

  • 17. SAR studies of 3-arylpropionic acids as potent and selective agonists of sphingosine-1-phosphate receptor-1 (S1P1) with enhanced pharmacokinetic properties.
    Yan L, Huo P, Hale JJ, Mills SG, Hajdu R, Keohane CA, Rosenbach MJ, Milligan JA, Shei GJ, Chrebet G, Bergstrom J, Card D, Mandala SM.
    Bioorg Med Chem Lett; 2007 Feb 01; 17(3):828-31. PubMed ID: 17092714
    [Abstract] [Full Text] [Related]

  • 18. Substituted indole-2-carboxylates as in vivo potent antagonists acting as the strychnine-insensitive glycine binding site.
    Di Fabio R, Capelli AM, Conti N, Cugola A, Donati D, Feriani A, Gastaldi P, Gaviraghi G, Hewkin CT, Micheli F, Missio A, Mugnaini M, Pecunioso A, Quaglia AM, Ratti E, Rossi L, Tedesco G, Trist DG, Reggiani A.
    J Med Chem; 1997 Mar 14; 40(6):841-50. PubMed ID: 9083472
    [Abstract] [Full Text] [Related]

  • 19. Structure-activity relationship analysis of the peptide deformylase inhibitor 5-bromo-1H-indole-3-acetohydroxamic acid.
    Petit S, Duroc Y, Larue V, Giglione C, Léon C, Soulama C, Denis A, Dardel F, Meinnel T, Artaud I.
    ChemMedChem; 2009 Feb 14; 4(2):261-75. PubMed ID: 19053131
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis, and pharmacological evaluation of some 2-[4-morpholino]-3-aryl-5-substituted thiophenes as novel anti-inflammatory agents: generation of a novel anti-inflammatory pharmacophore.
    Pillai AD, Rathod PD, Xavier FP, Vasu KK, Padh H, Sudarsanam V.
    Bioorg Med Chem; 2004 Sep 01; 12(17):4667-71. PubMed ID: 15358292
    [Abstract] [Full Text] [Related]

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