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544 related items for PubMed ID: 9260909

  • 21. Overexpression of Bcl-2 or Bcl-xL inhibits Ara-C-induced CPP32/Yama protease activity and apoptosis of human acute myelogenous leukemia HL-60 cells.
    Ibrado AM, Huang Y, Fang G, Liu L, Bhalla K.
    Cancer Res; 1996 Oct 15; 56(20):4743-8. PubMed ID: 8840993
    [Abstract] [Full Text] [Related]

  • 22. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
    Akiyama T, Yoshida T, Tsujita T, Shimizu M, Mizukami T, Okabe M, Akinaga S.
    Cancer Res; 1997 Apr 15; 57(8):1495-501. PubMed ID: 9108451
    [Abstract] [Full Text] [Related]

  • 23. Activation of CPP32-like proteases is not sufficient to trigger apoptosis: inhibition of apoptosis by agents that suppress activation of AP24, but not CPP32-like activity.
    Wright SC, Schellenberger U, Wang H, Kinder DH, Talhouk JW, Larrick JW.
    J Exp Med; 1997 Oct 06; 186(7):1107-17. PubMed ID: 9314559
    [Abstract] [Full Text] [Related]

  • 24. Characterization of adriamycin-induced G2 arrest and its abrogation by caffeine in FL-amnion cells with or without p53.
    Minemoto Y, Gannon J, Masutani M, Nakagama H, Sasagawa T, Inoue M, Masamune Y, Yamashita K.
    Exp Cell Res; 2001 Jan 01; 262(1):37-48. PubMed ID: 11120603
    [Abstract] [Full Text] [Related]

  • 25. Decrease in susceptibility toward induction of apoptosis and alteration in G1 checkpoint function as determinants of resistance of human lung cancer cells against the antisignaling drug UCN-01 (7-Hydroxystaurosporine).
    Sugiyama K, Akiyama T, Shimizu M, Tamaoki T, Courage C, Gescher A, Akinaga S.
    Cancer Res; 1999 Sep 01; 59(17):4406-12. PubMed ID: 10485490
    [Abstract] [Full Text] [Related]

  • 26. UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.
    Wang Q, Fan S, Eastman A, Worland PJ, Sausville EA, O'Connor PM.
    J Natl Cancer Inst; 1996 Jul 17; 88(14):956-65. PubMed ID: 8667426
    [Abstract] [Full Text] [Related]

  • 27. Caspase-3 is required in the apoptotic disintegration of the nuclear matrix.
    Kivinen K, Kallajoki M, Taimen P.
    Exp Cell Res; 2005 Nov 15; 311(1):62-73. PubMed ID: 16199031
    [Abstract] [Full Text] [Related]

  • 28. Merbarone, a catalytic inhibitor of DNA topoisomerase II, induces apoptosis in CEM cells through activation of ICE/CED-3-like protease.
    Khélifa T, Beck WT.
    Mol Pharmacol; 1999 Mar 15; 55(3):548-56. PubMed ID: 10051540
    [Abstract] [Full Text] [Related]

  • 29. Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1).
    Patel V, Lahusen T, Leethanakul C, Igishi T, Kremer M, Quintanilla-Martinez L, Ensley JF, Sausville EA, Gutkind JS, Senderowicz AM.
    Clin Cancer Res; 2002 Nov 15; 8(11):3549-60. PubMed ID: 12429646
    [Abstract] [Full Text] [Related]

  • 30. Role of serine and ICE-like proteases in induction of apoptosis by etoposide in human leukemia HL-60 cells.
    Yoshida A, Takauji R, Inuzuka M, Ueda T, Nakamura T.
    Leukemia; 1996 May 15; 10(5):821-4. PubMed ID: 8656677
    [Abstract] [Full Text] [Related]

  • 31. The temporal relationship between protein phosphatase, ICE/CED-3 proteases, intracellular acidification, and DNA fragmentation in apoptosis.
    Wolf CM, Reynolds JE, Morana SJ, Eastman A.
    Exp Cell Res; 1997 Jan 10; 230(1):22-7. PubMed ID: 9013702
    [Abstract] [Full Text] [Related]

  • 32. Aspirin induces cell death and caspase-dependent phosphatidylserine externalization in HT-29 human colon adenocarcinoma cells.
    Castaño E, Dalmau M, Barragán M, Pueyo G, Bartrons R, Gil J.
    Br J Cancer; 1999 Sep 10; 81(2):294-9. PubMed ID: 10496355
    [Abstract] [Full Text] [Related]

  • 33. Activation of the Fas pathway independently of Fas ligand during apoptosis induced by camptothecin in p53 mutant human colon carcinoma cells.
    Shao RG, Cao CX, Nieves-Neira W, Dimanche-Boitrel MT, Solary E, Pommier Y.
    Oncogene; 2001 Apr 05; 20(15):1852-9. PubMed ID: 11313933
    [Abstract] [Full Text] [Related]

  • 34. Combretastatin-A4 prodrug induces mitotic catastrophe in chronic lymphocytic leukemia cell line independent of caspase activation and poly(ADP-ribose) polymerase cleavage.
    Nabha SM, Mohammad RM, Dandashi MH, Coupaye-Gerard B, Aboukameel A, Pettit GR, Al-Katib AM.
    Clin Cancer Res; 2002 Aug 05; 8(8):2735-41. PubMed ID: 12171907
    [Abstract] [Full Text] [Related]

  • 35. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells.
    Cheong JW, Chong SY, Kim JY, Eom JI, Jeung HK, Maeng HY, Lee ST, Min YH.
    Clin Cancer Res; 2003 Oct 15; 9(13):5018-27. PubMed ID: 14581377
    [Abstract] [Full Text] [Related]

  • 36. Processing/activation of at least four interleukin-1beta converting enzyme-like proteases occurs during the execution phase of apoptosis in human monocytic tumor cells.
    MacFarlane M, Cain K, Sun XM, Alnemri ES, Cohen GM.
    J Cell Biol; 1997 Apr 21; 137(2):469-79. PubMed ID: 9128256
    [Abstract] [Full Text] [Related]

  • 37. The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-x(L) protein.
    Bhonde MR, Hanski ML, Magrini R, Moorthy D, Müller A, Sausville EA, Kohno K, Wiegand P, Daniel PT, Zeitz M, Hanski C.
    Oncogene; 2005 Jan 06; 24(1):148-56. PubMed ID: 15467762
    [Abstract] [Full Text] [Related]

  • 38. Interactions between 2-fluoroadenine 9-beta-D-arabinofuranoside and the kinase inhibitor UCN-01 in human leukemia and lymphoma cells.
    Harvey S, Decker R, Dai Y, Schaefer G, Tang L, Kramer L, Dent P, Grant S.
    Clin Cancer Res; 2001 Feb 06; 7(2):320-30. PubMed ID: 11234887
    [Abstract] [Full Text] [Related]

  • 39. UCN-01 inhibits p53 up-regulation and abrogates gamma-radiation-induced G(2)-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1.
    Yu Q, La Rose J, Zhang H, Takemura H, Kohn KW, Pommier Y.
    Cancer Res; 2002 Oct 15; 62(20):5743-8. PubMed ID: 12384533
    [Abstract] [Full Text] [Related]

  • 40. Induction of colon cancer cell death by 7-hydroxystaurosporine (UCN-01) is associated with increased p38 MAPK and decreased Bcl-xL.
    Chan UP, Lee JF, Wang SH, Leung KL, Chen GG.
    Anticancer Drugs; 2003 Oct 15; 14(9):761-6. PubMed ID: 14551511
    [Abstract] [Full Text] [Related]

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