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150 related items for PubMed ID: 9262323

  • 1. Estimation of transplacental and nonplacental diphenhydramine clearances in the fetal lamb: the impact of fetal first-pass hepatic drug uptake.
    Kumar S, Tonn GR, Kwan E, Hall C, Riggs KW, Axelson JE, Rurak DW.
    J Pharmacol Exp Ther; 1997 Aug; 282(2):617-32. PubMed ID: 9262323
    [Abstract] [Full Text] [Related]

  • 2. Hepatic first-pass uptake of diphenhydramine. A comparative study between fetal and adult sheep.
    Tonn GR, Kwan E, Hall C, Riggs KW, Axelson JE, Rurak DW.
    Drug Metab Dispos; 1996 Mar; 24(3):273-81. PubMed ID: 8820416
    [Abstract] [Full Text] [Related]

  • 3. Diphenhydramine disposition in the sheep maternal-placental-fetal unit: gestational age, plasma drug protein binding, and umbilical blood flow effects on clearance.
    Kumar S, Tonn GR, Riggs KW, Rurak DW.
    Drug Metab Dispos; 2000 Mar; 28(3):279-85. PubMed ID: 10681371
    [Abstract] [Full Text] [Related]

  • 4. Comparative formation, distribution, and elimination kinetics of diphenylmethoxyacetic acid (a diphenhydramine metabolite) in maternal and fetal sheep.
    Kumar S, Riggs KW, Rurak DW.
    Drug Metab Dispos; 1999 Apr; 27(4):463-70. PubMed ID: 10101141
    [Abstract] [Full Text] [Related]

  • 5. Diphenhydramine disposition in the sheep maternal-placental-fetal unit: determinants of plasma drug concentrations in the mother and the fetus.
    Kumar S, Tonn GR, Riggs KW, Rurak DW.
    J Pharm Sci; 1999 Dec; 88(12):1259-65. PubMed ID: 10585220
    [Abstract] [Full Text] [Related]

  • 6. Role of the liver and gut in systemic diphenhydramine clearance in adult nonpregnant sheep.
    Kumar S, Riggs KW, Rurak DW.
    Drug Metab Dispos; 1999 Feb; 27(2):297-302. PubMed ID: 9929519
    [Abstract] [Full Text] [Related]

  • 7. Transplacental and nonplacental clearances of diphenhydramine in the chronically instrumented pregnant sheep.
    Yoo SD, Rurak DW, Taylor SM, Axelson JE.
    J Pharm Sci; 1993 Feb; 82(2):145-9. PubMed ID: 8445526
    [Abstract] [Full Text] [Related]

  • 8. Disposition of valproic acid in maternal, fetal, and newborn sheep. I: placental transfer, plasma protein binding, and clearance.
    Kumar S, Wong H, Yeung SA, Riggs KW, Abbott FS, Rurak DW.
    Drug Metab Dispos; 2000 Jul; 28(7):845-56. PubMed ID: 10859159
    [Abstract] [Full Text] [Related]

  • 9. The use of microdialysis for the study of drug kinetics: central nervous system pharmacokinetics of diphenhydramine in fetal, newborn, and adult sheep.
    Au-Yeung SC, Riggs KW, Gruber N, Rurak DW.
    Drug Metab Dispos; 2007 Aug; 35(8):1285-91. PubMed ID: 17485495
    [Abstract] [Full Text] [Related]

  • 10. Simultaneous analysis of diphenhydramine and a stable isotope analog (2H10)diphenhydramine using capillary gas chromatography with mass selective detection in biological fluids from chronically instrumented pregnant ewes.
    Tonn GR, Mutlib A, Abbott FS, Rurak DW, Axelson JE.
    Biol Mass Spectrom; 1993 Nov; 22(11):633-42. PubMed ID: 8251550
    [Abstract] [Full Text] [Related]

  • 11. The contribution of transplacental clearances and fetal clearance to drug disposition in the ovine maternal-fetal unit.
    Szeto HH, Umans JG, Rubinow SI.
    Drug Metab Dispos; 1982 Nov; 10(4):382-6. PubMed ID: 6126338
    [Abstract] [Full Text] [Related]

  • 12. Simultaneous determination of diphenhydramine, its N-oxide metabolite and their deuterium-labeled analogues in ovine plasma and urine using liquid chromatography/electrospray tandem mass spectrometry.
    Kumar S, Rurak DW, Riggs KW.
    J Mass Spectrom; 1998 Dec; 33(12):1171-81. PubMed ID: 9875521
    [Abstract] [Full Text] [Related]

  • 13. A pharmacokinetic study of diphenhydramine transport across the blood-brain barrier in adult sheep: potential involvement of a carrier-mediated mechanism.
    Au-Yeung SC, Rurak DW, Gruber N, Riggs KW.
    Drug Metab Dispos; 2006 Jun; 34(6):955-60. PubMed ID: 16510542
    [Abstract] [Full Text] [Related]

  • 14. Pharmacokinetics and renal excretion of diphenhydramine and its metabolites, diphenylmethoxyacetic acid and diphenhydramine-N-oxide, in developing lambs.
    Wong H, Kumar S, Riggs KW, Rurak DW.
    J Pharm Sci; 2000 Oct; 89(10):1362-70. PubMed ID: 10980511
    [Abstract] [Full Text] [Related]

  • 15. Drug disposition and effects in the fetus.
    Rurak DW, Wright MR, Axelson JE.
    J Dev Physiol; 1991 Jan; 15(1):33-44. PubMed ID: 1678754
    [Abstract] [Full Text] [Related]

  • 16. Placental transfer and renal elimination of cimetidine in maternal and fetal sheep.
    Mihaly GW, Jones DB, Morgan DJ, Ching MS, Webster LK, Smallwood RA, Hardy KJ.
    J Pharmacol Exp Ther; 1983 Nov; 227(2):441-5. PubMed ID: 6631723
    [Abstract] [Full Text] [Related]

  • 17. Pharmacokinetic studies of the disposition of acetaminophen in the sheep maternal-placental-fetal unit.
    Wang LH, Rudolph AM, Benet LZ.
    J Pharmacol Exp Ther; 1986 Jul; 238(1):198-205. PubMed ID: 3723398
    [Abstract] [Full Text] [Related]

  • 18. Study of the placental transfer of cisapride in sheep. Plasma levels in the pregnant ewe, the fetus, and the lamb.
    Veereman-Wauters G, Monbaliu J, Meuldermans W, Woestenborghs R, Verlinden M, Heykants J, Rudolph CD.
    Drug Metab Dispos; 1991 Jul; 19(1):168-72. PubMed ID: 1673393
    [Abstract] [Full Text] [Related]

  • 19. Placental transfer and fetal metabolism of zidovudine in the baboon.
    Garland M, Szeto HH, Daniel SS, Tropper PJ, Myers MM, Stark RI.
    Pediatr Res; 1998 Jul; 44(1):47-53. PubMed ID: 9667370
    [Abstract] [Full Text] [Related]

  • 20. Lactate uptake by the fetal sheep liver.
    Gleason CA, Rudolph CD, Bristow J, Itskovitz J, Rudolph AM.
    J Dev Physiol; 1985 Jun; 7(3):177-83. PubMed ID: 4008897
    [Abstract] [Full Text] [Related]

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