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186 related items for PubMed ID: 9269775

  • 1. Significance of RGD loop and C-terminal domain of echistatin for recognition of alphaIIb beta3 and alpha(v) beta3 integrins and expression of ligand-induced binding site.
    Marcinkiewicz C, Vijay-Kumar S, McLane MA, Niewiarowski S.
    Blood; 1997 Aug 15; 90(4):1565-75. PubMed ID: 9269775
    [Abstract] [Full Text] [Related]

  • 2. Immunological characterization of eristostatin and echistatin binding sites on alpha IIb beta 3 and alpha V beta 3 integrins.
    Marcinkiewicz C, Rosenthal LA, Mosser DM, Kunicki TJ, Niewiarowski S.
    Biochem J; 1996 Aug 01; 317 ( Pt 3)(Pt 3):817-25. PubMed ID: 8760368
    [Abstract] [Full Text] [Related]

  • 3. Importance of the structure of the RGD-containing loop in the disintegrins echistatin and eristostatin for recognition of alpha IIb beta 3 and alpha v beta 3 integrins.
    McLane MA, Vijay-Kumar S, Marcinkiewicz C, Calvete JJ, Niewiarowski S.
    FEBS Lett; 1996 Aug 05; 391(1-2):139-43. PubMed ID: 8706902
    [Abstract] [Full Text] [Related]

  • 4. The disintegrin echistatin stabilizes integrin alphaIIbbeta3's open conformation and promotes its oligomerization.
    Hantgan RR, Stahle MC, Connor JH, Lyles DS, Horita DA, Rocco M, Nagaswami C, Weisel JW, McLane MA.
    J Mol Biol; 2004 Oct 01; 342(5):1625-36. PubMed ID: 15364586
    [Abstract] [Full Text] [Related]

  • 5. Structural requirements of echistatin for the recognition of alpha(v)beta(3) and alpha(5)beta(1) integrins.
    Wierzbicka-Patynowski I, Niewiarowski S, Marcinkiewicz C, Calvete JJ, Marcinkiewicz MM, McLane MA.
    J Biol Chem; 1999 Dec 31; 274(53):37809-14. PubMed ID: 10608843
    [Abstract] [Full Text] [Related]

  • 6. Identification of the principal binding site for RGD-containing ligands in the alpha(V)beta(3) integrin: a photoaffinity cross-linking study.
    Yahalom D, Wittelsberger A, Mierke DF, Rosenblatt M, Alexander JM, Chorev M.
    Biochemistry; 2002 Jul 02; 41(26):8321-31. PubMed ID: 12081480
    [Abstract] [Full Text] [Related]

  • 7. Chloramine T-induced structural and biochemical changes in echistatin.
    Kumar CC, Nie H, Armstrong L, Zhang R, Vijay-Kumar S, Tsarbopoulos A.
    FEBS Lett; 1998 Jun 16; 429(3):239-48. PubMed ID: 9662425
    [Abstract] [Full Text] [Related]

  • 8. Modulation of RGD sequence motifs regulates disintegrin recognition of alphaIIb beta3 and alpha5 beta1 integrin complexes. Replacement of elegantin alanine-50 with proline, N-terminal to the RGD sequence, diminishes recognition of the alpha5 beta1 complex with restoration induced by Mn2+ cation.
    Rahman S, Aitken A, Flynn G, Formstone C, Savidge GF.
    Biochem J; 1998 Oct 15; 335 ( Pt 2)(Pt 2):247-57. PubMed ID: 9761721
    [Abstract] [Full Text] [Related]

  • 9. An αIIb β3 antagonist prevents thrombosis without causing Fc receptor γ-chain IIa-mediated thrombocytopenia.
    Kuo YJ, Chen YR, Hsu CC, Peng HC, Huang TF.
    J Thromb Haemost; 2017 Nov 15; 15(11):2230-2244. PubMed ID: 28815933
    [Abstract] [Full Text] [Related]

  • 10. Integrin alphaIIbbeta3:ligand interactions are linked to binding-site remodeling.
    Hantgan RR, Stahle MC, Connor JH, Horita DA, Rocco M, McLane MA, Yakovlev S, Medved L.
    Protein Sci; 2006 Aug 15; 15(8):1893-906. PubMed ID: 16877710
    [Abstract] [Full Text] [Related]

  • 11. The presence of the WGD motif in CC8 heterodimeric disintegrin increases its inhibitory effect on alphaII(b)beta3, alpha(v)beta3, and alpha5beta1 integrins.
    Calvete JJ, Fox JW, Agelan A, Niewiarowski S, Marcinkiewicz C.
    Biochemistry; 2002 Feb 12; 41(6):2014-21. PubMed ID: 11827548
    [Abstract] [Full Text] [Related]

  • 12. Binding of the snake venom-derived proteins applaggin and echistatin to the arginine-glycine-aspartic acid recognition site(s) on platelet glycoprotein IIb.IIIa complex inhibits receptor function.
    Savage B, Marzec UM, Chao BH, Harker LA, Maraganore JM, Ruggeri ZM.
    J Biol Chem; 1990 Jul 15; 265(20):11766-72. PubMed ID: 2365698
    [Abstract] [Full Text] [Related]

  • 13. Antibodies causing thrombocytopenia in patients treated with RGD-mimetic platelet inhibitors recognize ligand-specific conformers of αIIb/β3 integrin.
    Bougie DW, Rasmussen M, Zhu J, Aster RH.
    Blood; 2012 Jun 28; 119(26):6317-25. PubMed ID: 22490676
    [Abstract] [Full Text] [Related]

  • 14. RGD-mutants of B-lymphotropic polyomavirus capsids specifically bind to alpha(v)beta3 integrin.
    Langner J, Neumann B, Goodman SL, Pawlita M.
    Arch Virol; 2004 Oct 28; 149(10):1877-96. PubMed ID: 15290355
    [Abstract] [Full Text] [Related]

  • 15. Differential recognition of snake venom proteins expressing specific Arg-Gly-Asp (RGD) sequence motifs by wild-type and variant integrin alphaIIbbeta3: further evidence for distinct sites of RGD ligand recognition exhibiting negative allostery.
    Rahman S, Flynn G, Aitken A, Patel Y, Hussain F, Lu X, Loftus JC, French D, Wijelath E, Strand K, Savidge GF.
    Biochem J; 2000 Feb 01; 345 Pt 3(Pt 3):701-9. PubMed ID: 10642531
    [Abstract] [Full Text] [Related]

  • 16. Functional and computational studies of the ligand-associated metal binding site of beta3 integrins.
    Murcia M, Jirouskova M, Li J, Coller BS, Filizola M.
    Proteins; 2008 Jun 01; 71(4):1779-91. PubMed ID: 18175315
    [Abstract] [Full Text] [Related]

  • 17. β-Subunit Binding Is Sufficient for Ligands to Open the Integrin αIIbβ3 Headpiece.
    Lin FY, Zhu J, Eng ET, Hudson NE, Springer TA.
    J Biol Chem; 2016 Feb 26; 291(9):4537-46. PubMed ID: 26631735
    [Abstract] [Full Text] [Related]

  • 18. Identification of a contact domain between echistatin and the integrin alpha(v)beta(3) by photoaffinity cross-linking.
    Scheibler L, Mierke DF, Bitan G, Rosenblatt M, Chorev M.
    Biochemistry; 2001 Dec 18; 40(50):15117-26. PubMed ID: 11735394
    [Abstract] [Full Text] [Related]

  • 19. Disintegrin interaction with alpha V beta 3 integrin on human umbilical vein endothelial cells: expression of ligand-induced binding site on beta 3 subunit.
    Juliano D, Wang Y, Marcinkiewicz C, Rosenthal LA, Stewart GJ, Niewiarowski S.
    Exp Cell Res; 1996 May 25; 225(1):132-42. PubMed ID: 8635506
    [Abstract] [Full Text] [Related]

  • 20. A molecular basis for affinity modulation of Fab ligand binding to integrin alphaIIb beta3.
    Kunicki TJ, Annis DS, Deng YJ, Loftus JC, Shattil SJ.
    J Biol Chem; 1996 Aug 23; 271(34):20315-21. PubMed ID: 8702765
    [Abstract] [Full Text] [Related]

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