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263 related items for PubMed ID: 9286751

  • 1. Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro.
    Frith JC, Mönkkönen J, Blackburn GM, Russell RG, Rogers MJ.
    J Bone Miner Res; 1997 Sep; 12(9):1358-67. PubMed ID: 9286751
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  • 2. Growth inhibition of macrophage-like and other cell types by liposome-encapsulated, calcium-bound, and free bisphosphonates in vitro.
    Mönkkönen J, Taskinen M, Auriola SO, Urtti A.
    J Drug Target; 1994 Sep; 2(4):299-308. PubMed ID: 7858955
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  • 3. The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate: evidence for the formation in vivo of a metabolite that inhibits bone resorption and causes osteoclast and macrophage apoptosis.
    Frith JC, Mönkkönen J, Auriola S, Mönkkönen H, Rogers MJ.
    Arthritis Rheum; 2001 Sep; 44(9):2201-10. PubMed ID: 11592386
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  • 5. Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite.
    Lehenkari PP, Kellinsalmi M, Näpänkangas JP, Ylitalo KV, Mönkkönen J, Rogers MJ, Azhayev A, Väänänen HK, Hassinen IE.
    Mol Pharmacol; 2002 May; 61(5):1255-62. PubMed ID: 11961144
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  • 8. The cellular uptake and metabolism of clodronate in RAW 264 macrophages.
    Mönkkönen H, Rogers MJ, Makkonen N, Niva S, Auriola S, Mönkkönen J.
    Pharm Res; 2001 Nov; 18(11):1550-5. PubMed ID: 11758762
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  • 10. Characteristics of clodronate-induced apoptosis in osteoclasts and macrophages.
    Selander KS, Mönkkönen J, Karhukorpi EK, Härkönen P, Hannuniemi R, Väänänen HK.
    Mol Pharmacol; 1996 Nov; 50(5):1127-38. PubMed ID: 8913344
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  • 13. Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway.
    Virtanen SS, Väänänen HK, Härkönen PL, Lakkakorpi PT.
    Cancer Res; 2002 May 01; 62(9):2708-14. PubMed ID: 11980672
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  • 16. Liposomes for targeting of antigens and drugs: immunoadjuvant activity and liposome-mediated depletion of macrophages.
    van Rooijen N.
    J Drug Target; 2008 Aug 01; 16(7):529-34. PubMed ID: 18686122
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  • 17. Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.
    Luckman SP, Hughes DE, Coxon FP, Graham R, Russell G, Rogers MJ.
    J Bone Miner Res; 1998 Apr 01; 13(4):581-9. PubMed ID: 9556058
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