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277 related items for PubMed ID: 9299553

  • 1. Adenovirus-mediated transduction with human glial cell line-derived neurotrophic factor gene prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopamine depletion in striatum of mouse brain.
    Kojima H, Abiru Y, Sakajiri K, Watabe K, Ohishi N, Takamori M, Hatanaka H, Yagi K.
    Biochem Biophys Res Commun; 1997 Sep 18; 238(2):569-73. PubMed ID: 9299553
    [Abstract] [Full Text] [Related]

  • 2. Differential effects of glial cell line-derived neurotrophic factor (GDNF) in the striatum and substantia nigra of the aged Parkinsonian rat.
    Connor B, Kozlowski DA, Schallert T, Tillerson JL, Davidson BL, Bohn MC.
    Gene Ther; 1999 Dec 18; 6(12):1936-51. PubMed ID: 10637445
    [Abstract] [Full Text] [Related]

  • 3. Delayed gene therapy of glial cell line-derived neurotrophic factor is efficacious in a rat model of Parkinson's disease.
    Zheng JS, Tang LL, Zheng SS, Zhan RY, Zhou YQ, Goudreau J, Kaufman D, Chen AF.
    Brain Res Mol Brain Res; 2005 Mar 24; 134(1):155-61. PubMed ID: 15790539
    [Abstract] [Full Text] [Related]

  • 4. Behavioral and cellular protection of rat dopaminergic neurons by an adenoviral vector encoding glial cell line-derived neurotrophic factor.
    Choi-Lundberg DL, Lin Q, Schallert T, Crippens D, Davidson BL, Chang YN, Chiang YL, Qian J, Bardwaj L, Bohn MC.
    Exp Neurol; 1998 Dec 24; 154(2):261-75. PubMed ID: 9878166
    [Abstract] [Full Text] [Related]

  • 5. Astrocyte delivery of glial cell line-derived neurotrophic factor in a mouse model of Parkinson's disease.
    Cunningham LA, Su C.
    Exp Neurol; 2002 Apr 24; 174(2):230-42. PubMed ID: 11922664
    [Abstract] [Full Text] [Related]

  • 6. Long-term glial cell line-derived neurotrophic factor overexpression in the intact nigrostriatal system in rats leads to a decrease of dopamine and increase of tetrahydrobiopterin production.
    Sajadi A, Bauer M, Thöny B, Aebischer P.
    J Neurochem; 2005 Jun 24; 93(6):1482-6. PubMed ID: 15935064
    [Abstract] [Full Text] [Related]

  • 7. Catalpol attenuates MPTP induced neuronal degeneration of nigral-striatal dopaminergic pathway in mice through elevating glial cell derived neurotrophic factor in striatum.
    Xu G, Xiong Z, Yong Y, Wang Z, Ke Z, Xia Z, Hu Y.
    Neuroscience; 2010 Apr 28; 167(1):174-84. PubMed ID: 20123001
    [Abstract] [Full Text] [Related]

  • 8. Glial cell line-derived neurotrophic factor (GDNF) gene delivery protects dopaminergic terminals from degeneration.
    Connor B, Kozlowski DA, Unnerstall JR, Elsworth JD, Tillerson JL, Schallert T, Bohn MC.
    Exp Neurol; 2001 May 28; 169(1):83-95. PubMed ID: 11312561
    [Abstract] [Full Text] [Related]

  • 9. Identification of brain-derived neurotrophic factor in nestin-expressing astroglial cells in the neostriatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice.
    Chen LW, Hu HJ, Liu HL, Yung KK, Chan YS.
    Neuroscience; 2004 May 28; 126(4):941-53. PubMed ID: 15207328
    [Abstract] [Full Text] [Related]

  • 10. GDNF fails to exert neuroprotection in a rat α-synuclein model of Parkinson's disease.
    Decressac M, Ulusoy A, Mattsson B, Georgievska B, Romero-Ramos M, Kirik D, Björklund A.
    Brain; 2011 Aug 28; 134(Pt 8):2302-11. PubMed ID: 21712347
    [Abstract] [Full Text] [Related]

  • 11. Protection of dopaminergic nigrostriatal afferents by GDNF delivered by microspheres in a rodent model of Parkinson's disease.
    Gouhier C, Chalon S, Aubert-Pouessel A, Venier-Julienne MC, Jollivet C, Benoit JP, Guilloteau D.
    Synapse; 2002 Jun 01; 44(3):124-31. PubMed ID: 11954043
    [Abstract] [Full Text] [Related]

  • 12. An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's disease.
    Mochizuki H, Hayakawa H, Migita M, Shibata M, Tanaka R, Suzuki A, Shimo-Nakanishi Y, Urabe T, Yamada M, Tamayose K, Shimada T, Miura M, Mizuno Y.
    Proc Natl Acad Sci U S A; 2001 Sep 11; 98(19):10918-23. PubMed ID: 11535810
    [Abstract] [Full Text] [Related]

  • 13. Localization of nerve growth factor, neurotrophin-3, and glial cell line-derived neurotrophic factor in nestin-expressing reactive astrocytes in the caudate-putamen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57/Bl mice.
    Chen LW, Zhang JP, Kwok-Yan Shum D, Chan YS.
    J Comp Neurol; 2006 Aug 20; 497(6):898-909. PubMed ID: 16802332
    [Abstract] [Full Text] [Related]

  • 14. Lentiviral vectors as a gene delivery system in the mouse midbrain: cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF.
    Bensadoun JC, Déglon N, Tseng JL, Ridet JL, Zurn AD, Aebischer P.
    Exp Neurol; 2000 Jul 20; 164(1):15-24. PubMed ID: 10877911
    [Abstract] [Full Text] [Related]

  • 15. Doxycycline-regulated co-expression of GDNF and TH in PC12 cells.
    Wang JJ, Zhang T, Niu DB, Wang K, Li KR, Xue B, Wang XM.
    Neurosci Lett; 2006 Jun 19; 401(1-2):142-5. PubMed ID: 16584838
    [Abstract] [Full Text] [Related]

  • 16. Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo.
    Tomac A, Lindqvist E, Lin LF, Ogren SO, Young D, Hoffer BJ, Olson L.
    Nature; 1995 Jan 26; 373(6512):335-9. PubMed ID: 7830766
    [Abstract] [Full Text] [Related]

  • 17. Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease.
    Wang L, Muramatsu S, Lu Y, Ikeguchi K, Fujimoto K, Okada T, Mizukami H, Hanazono Y, Kume A, Urano F, Ichinose H, Nagatsu T, Nakano I, Ozawa K.
    Gene Ther; 2002 Mar 26; 9(6):381-9. PubMed ID: 11960314
    [Abstract] [Full Text] [Related]

  • 18. Delivery of GDNF by an E1,E3/E4 deleted adenoviral vector and driven by a GFAP promoter prevents dopaminergic neuron degeneration in a rat model of Parkinson's disease.
    Do Thi NA, Saillour P, Ferrero L, Dedieu JF, Mallet J, Paunio T.
    Gene Ther; 2004 May 26; 11(9):746-56. PubMed ID: 14724667
    [Abstract] [Full Text] [Related]

  • 19. Functional recovery in parkinsonian monkeys treated with GDNF.
    Gash DM, Zhang Z, Ovadia A, Cass WA, Yi A, Simmerman L, Russell D, Martin D, Lapchak PA, Collins F, Hoffer BJ, Gerhardt GA.
    Nature; 1996 Mar 21; 380(6571):252-5. PubMed ID: 8637574
    [Abstract] [Full Text] [Related]

  • 20. Bcl-2 and GDNF delivered by HSV-mediated gene transfer act additively to protect dopaminergic neurons from 6-OHDA-induced degeneration.
    Natsume A, Mata M, Goss J, Huang S, Wolfe D, Oligino T, Glorioso J, Fink DJ.
    Exp Neurol; 2001 Jun 21; 169(2):231-8. PubMed ID: 11358438
    [Abstract] [Full Text] [Related]


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