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114 related items for PubMed ID: 9303389

  • 1. Construction and characterization of an OHIO-1 beta-lactamase bearing Met69Ile and Gly238Ser mutations.
    Bonomo RA, Knox JR, Rudin SD, Shlaes DM.
    Antimicrob Agents Chemother; 1997 Sep; 41(9):1940-3. PubMed ID: 9303389
    [Abstract] [Full Text] [Related]

  • 2. Mutagenesis of amino acid residues in the SHV-1 beta-lactamase: the premier role of Gly238Ser in penicillin and cephalosporin resistance.
    Hujer AM, Hujer KM, Bonomo RA.
    Biochim Biophys Acta; 2001 May 05; 1547(1):37-50. PubMed ID: 11343789
    [Abstract] [Full Text] [Related]

  • 3. Kinetic analysis of an inhibitor-resistant variant of the OHIO-1 beta-lactamase, an SHV-family class A enzyme.
    Lin S, Thomas M, Shlaes DM, Rudin SD, Knox JR, Anderson V, Bonomo RA.
    Biochem J; 1998 Jul 15; 333 ( Pt 2)(Pt 2):395-400. PubMed ID: 9735103
    [Abstract] [Full Text] [Related]

  • 4. Role of Asp104 in the SHV beta-lactamase.
    Bethel CR, Hujer AM, Hujer KM, Thomson JM, Ruszczycky MW, Anderson VE, Pusztai-Carey M, Taracila M, Helfand MS, Bonomo RA.
    Antimicrob Agents Chemother; 2006 Dec 15; 50(12):4124-31. PubMed ID: 16982784
    [Abstract] [Full Text] [Related]

  • 5. OHIO-1 beta-lactamase mutants: the Arg244Ser mutant and resistance to beta-lactams and beta-lactamase inhibitors.
    Lin S, Thomas M, Mark S, Anderson V, Bonomo RA.
    Biochim Biophys Acta; 1999 Jun 15; 1432(1):125-36. PubMed ID: 10366735
    [Abstract] [Full Text] [Related]

  • 6. OHIO-1 beta-lactamase mutants: Asp179Gly mutation confers resistance to ceftazidime.
    Bonomo RA, Rudin SD, Shlaes DM.
    FEMS Microbiol Lett; 1997 Jul 15; 152(2):275-8. PubMed ID: 9231421
    [Abstract] [Full Text] [Related]

  • 7. Construction and characterization of mutants of the TEM-1 beta-lactamase containing amino acid substitutions associated with both extended-spectrum resistance and resistance to beta-lactamase inhibitors.
    Stapleton PD, Shannon KP, French GL.
    Antimicrob Agents Chemother; 1999 Aug 15; 43(8):1881-7. PubMed ID: 10428907
    [Abstract] [Full Text] [Related]

  • 8. Aspartic acid for asparagine substitution at position 276 reduces susceptibility to mechanism-based inhibitors in SHV-1 and SHV-5 beta-lactamases.
    Giakkoupi P, Tzelepi E, Legakis NJ, Tzouvelekis LS.
    J Antimicrob Chemother; 1999 Jan 15; 43(1):23-9. PubMed ID: 10381097
    [Abstract] [Full Text] [Related]

  • 9. Haemophilus influenzae bla(ROB-1) mutations in hypermutagenic deltaampC Escherichia coli conferring resistance to cefotaxime and beta-lactamase inhibitors and increased susceptibility to cefaclor.
    Galán JC, Morosini MI, Baquero MR, Reig M, Baquero F.
    Antimicrob Agents Chemother; 2003 Aug 15; 47(8):2551-7. PubMed ID: 12878518
    [Abstract] [Full Text] [Related]

  • 10. Mutations altering substrate specificity in OHIO-1, and SHV-1 family beta-lactamase.
    Shlaes DM, Currie-McCumber C.
    Biochem J; 1992 Jun 01; 284 ( Pt 2)(Pt 2):411-5. PubMed ID: 1599426
    [Abstract] [Full Text] [Related]

  • 11. Unexpected advanced generation cephalosporinase activity of the M69F variant of SHV beta-lactamase.
    Helfand MS, Hujer AM, Sönnichsen FD, Bonomo RA.
    J Biol Chem; 2002 Dec 06; 277(49):47719-23. PubMed ID: 12354765
    [Abstract] [Full Text] [Related]

  • 12. Complementary roles of mutations at positions 69 and 242 in a class A beta-lactamase.
    Bonomo RA, Dawes CG, Knox JR, Shlaes DM.
    Biochim Biophys Acta; 1995 Feb 22; 1247(1):113-20. PubMed ID: 7873579
    [Abstract] [Full Text] [Related]

  • 13. beta-Lactamase mutations far from the active site influence inhibitor binding.
    Bonomo RA, Dawes CG, Knox JR, Shlaes DM.
    Biochim Biophys Acta; 1995 Feb 22; 1247(1):121-5. PubMed ID: 7873581
    [Abstract] [Full Text] [Related]

  • 14. Tazobactam is a potent inactivator of selected inhibitor-resistant class A beta-lactamases.
    Bonomo RA, Rudin SA, Shlaes DM.
    FEMS Microbiol Lett; 1997 Mar 01; 148(1):59-62. PubMed ID: 9066111
    [Abstract] [Full Text] [Related]

  • 15. Substitution of Met-69 by Ala or Gly in TEM-1 beta-lactamase confer an increased susceptibility to clavulanic acid and other inhibitors.
    Madec S, Blin C, Krishnamoorthy R, Picard B, Chaibi el B, Fouchereau-Péron M, Labia R.
    FEMS Microbiol Lett; 2002 May 21; 211(1):13-6. PubMed ID: 12052544
    [Abstract] [Full Text] [Related]

  • 16. Mutant TEM beta-lactamase producing resistance to ceftazidime, ampicillins, and beta-lactamase inhibitors.
    Vakulenko S, Golemi D.
    Antimicrob Agents Chemother; 2002 Mar 21; 46(3):646-53. PubMed ID: 11850243
    [Abstract] [Full Text] [Related]

  • 17. Overcoming resistance to beta-lactamase inhibitors: comparing sulbactam to novel inhibitors against clavulanate resistant SHV enzymes with substitutions at Ambler position 244.
    Thomson JM, Distler AM, Bonomo RA.
    Biochemistry; 2007 Oct 09; 46(40):11361-8. PubMed ID: 17848099
    [Abstract] [Full Text] [Related]

  • 18. Deciphering the Evolution of Cephalosporin Resistance to Ceftolozane-Tazobactam in Pseudomonas aeruginosa.
    Barnes MD, Taracila MA, Rutter JD, Bethel CR, Galdadas I, Hujer AM, Caselli E, Prati F, Dekker JP, Papp-Wallace KM, Haider S, Bonomo RA.
    mBio; 2018 Dec 11; 9(6):. PubMed ID: 30538183
    [Abstract] [Full Text] [Related]

  • 19. Properties of mutant SHV-5 beta-lactamases constructed by substitution of isoleucine or valine for methionine at position 69.
    Giakkoupi P, Miriagou V, Gazouli M, Tzelepi E, Legakis NJ, Tzouvelekis LS.
    Antimicrob Agents Chemother; 1998 May 11; 42(5):1281-3. PubMed ID: 9593168
    [Abstract] [Full Text] [Related]

  • 20. Amino acid substitutions at Ambler position Gly238 in the SHV-1 beta-lactamase: exploring sequence requirements for resistance to penicillins and cephalosporins.
    Hujer AM, Hujer KM, Helfand MS, Anderson VE, Bonomo RA.
    Antimicrob Agents Chemother; 2002 Dec 11; 46(12):3971-7. PubMed ID: 12435703
    [Abstract] [Full Text] [Related]

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